1. Natural Products
  2. Antibiotics

Antibiotics

Antibiotics (137):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-10219
    Rapamycin 53123-88-9 99.93%
    Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
    Rapamycin
  • HY-12320
    Cycloheximide 66-81-9 99.86%
    Cycloheximide (Naramycin A), an antifungal antibiotic, is an eukaryote protein synthesis inhibitor, with IC50s of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively. Cycloheximide suppresses ferroptosis and inhibits autophagy.
    Cycloheximide
  • HY-17559
    Actinomycin D 50-76-0 99.58%
    Actinomycin D (Dactinomycin) inhibits DNA repair with an IC50 of 0.42 μM. Actinomycin D is an autophagy activator.
    Actinomycin D
  • HY-13316
    Mitomycin C 50-07-7 99.45%
    Mitomycin C (Ametycine) is a DNA cross-linking agent and induces DNA damaging. Mitomycin C is an antitumor drug and antibiotic that shows extraordinary ability to inhibit DNA synthesis. Mitomycin C is an ADC Cytotoxin and induces autophagy.
    Mitomycin C
  • HY-15142
    Doxorubicin hydrochloride 25316-40-9 99.47%
    Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride inhibits topoisomerase II, thus stopping DNA replication. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.
    Doxorubicin hydrochloride
  • HY-100558
    Bafilomycin A1 88899-55-2 99.43%
    Bafilomycin A1, a macrolide antibiotic isolated from the Streptomyces species, is a specific inhibitor of vacuolar-type H+ ATPase (V-ATPase). Bafilomycin A1 inhibits autophagy and induces apoptosis.
    Bafilomycin A1
  • HY-B1743A
    Puromycin Dihydrochloride 58-58-2 99.87%
    Puromycin Dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis.
    Puromycin Dihydrochloride
  • HY-A0098
    Tunicamycin 11089-65-9 99.69%
    Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.
    Tunicamycin
  • HY-100381
    Nigericin sodium salt 28643-80-3 >98.0%
    Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator.
    Nigericin sodium salt
  • HY-17561
    G-418 disulfate 108321-42-2 >98.0%
    G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
    G-418 disulfate
  • HY-17565
    Bleomycin sulfate 9041-93-4 >98.0%
    Bleomycin sulfate is a DNA synthesis inhibitor with potent antitumor activity.
    Bleomycin sulfate
  • HY-B0490
    Hygromycin B 31282-04-9 >98.00%
    Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
    Hygromycin B
  • HY-17362
    Vancomycin hydrochloride 1404-93-9 98.83%
    Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis.
    Vancomycin hydrochloride
  • HY-16589
    Oligomycin A 579-13-5 99.94%
    Oligomycin A, created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM; Oligomycin A shows anti-fungal activity.
    Oligomycin A
  • HY-B0470
    Neomycin sulfate 1405-10-3 >98.0%
    Neomycin sulfate is an aminoglycoside antibiotic used for preventing or treating bacterial infections.
    Neomycin sulfate
  • HY-B0221
    Amphotericin B 1397-89-3 >98.00%
    Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
    Amphotericin B
  • HY-13434
    Ionomycin 56092-81-0 >99.0%
    Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC).
    Ionomycin
  • HY-A0276
    Gentamicin sulfate 1405-41-0
    Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. It inhibits DNase I with an IC50 of 0.57 mM.
    Gentamicin sulfate
  • HY-B0272
    Rifampicin 13292-46-1 98.07%
    Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens.
    Rifampicin
  • HY-16566A
    Kanamycin sulfate 25389-94-0 >98.0%
    Kanamycin sulfate is an aminoglycoside bacteriocidal antibiotic which acts by binding to the bacterial 30S ribosomes.
    Kanamycin sulfate