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Antibiotics

 

Antibiotics (128):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-10219
    Rapamycin 53123-88-9 99.93%
    Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
    Rapamycin
  • HY-12320
    Cycloheximide 66-81-9 99.86%
    Cycloheximide (Naramycin A) is an eukaryote protein synthesis inhibitor, with IC50s of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively.
    Cycloheximide
  • HY-17559
    Actinomycin D 50-76-0 99.58%
    Actinomycin D inhibits DNA repair with an IC50 of 0.42 μM.
    Actinomycin D
  • HY-15142
    Doxorubicin hydrochloride 25316-40-9 99.47%
    Doxorubicin hydrochloride is a cytotoxic anthracycline antibiotic for the treatment of multiple cancers. The possible mechanisms by which doxorubicin acts in the cancer cell are intercalation into DNA and disruption of topoisomerase-II-mediated DNA repair. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase.
    Doxorubicin hydrochloride
  • HY-13316
    Mitomycin C 50-07-7 99.45%
    Mitomycin C is an antitumor drug and antibiotic that shows extraordinary ability to inhibit DNA synthesis. Mitomycin C is a DNA cross-linking agent, which induces DNA damaging.
    Mitomycin C
  • HY-100558
    Bafilomycin A1 88899-55-2 >99.0%
    Bafilomycin A1, a macrolide antibiotic isolated from the Streptomyces species, is a specific inhibitor of vacuolar-type H+ ATPase (V-ATPase). Bafilomycin A1 inhibits autophagy.
    Bafilomycin A1
  • HY-B1743A
    Puromycin Dihydrochloride 58-58-2 99.87%
    Puromycin Dihydrochloride (CL13900 dihydrochloride) is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibitsprotein synthesis.
    Puromycin Dihydrochloride
  • HY-A0098
    Tunicamycin 11089-65-9 99.69%
    Tunicamycin, a nucleoside antibiotic and an N-glycosylation inhibitor, causes unfolded protein response and is widely used as pharmacological inducer of endoplasmic reticulum stress. Tunicamycin causes G1 arrest.
    Tunicamycin
  • HY-100381
    Nigericin sodium salt 28643-80-3 >98.0%
    Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator.
    Nigericin sodium salt
  • HY-17561
    G-418 disulfate 108321-42-2 >98.0%
    G-418 (disulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
    G-418 disulfate
  • HY-B0490
    Hygromycin B 31282-04-9 >98.00%
    Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
    Hygromycin B
  • HY-17565
    Bleomycin sulfate 9041-93-4 >98.0%
    Bleomycin sulfate is a DNA synthesis inhibitor with potent antitumor activity.
    Bleomycin sulfate
  • HY-B0221
    Amphotericin B 1397-89-3 >98.00%
    Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
    Amphotericin B
  • HY-B0470
    Neomycin sulfate 1405-10-3 >98.0%
    Neomycin sulfate is an aminoglycoside antibiotic used for preventing or treating bacterial infections.
    Neomycin sulfate
  • HY-17362
    Vancomycin hydrochloride 1404-93-9 98.83%
    Vancomycin hydrochloride is an antibiotic for the treatment of bacterial infections. It acts by inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin also alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis.
    Vancomycin hydrochloride
  • HY-16589
    Oligomycin A 579-13-5 99.94%
    Oligomycin A, created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM; Oligomycin A shows anti-fungal activity.
    Oligomycin A
  • HY-13434
    Ionomycin 56092-81-0 >99.0%
    Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC).
    Ionomycin
  • HY-B0272
    Rifampicin 13292-46-1 98.07%
    Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens.
    Rifampicin
  • HY-A0276
    Gentamicin sulfate 1405-41-0
    Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. It inhibits DNase I with an IC50 of 0.57 mM.
    Gentamicin sulfate
  • HY-17412
    Minocycline hydrochloride 13614-98-7 99.57%
    Minocycline hydrochloride is a broad-spectrum tetracycline antibiotic, acting by binding to the bacterial 30S ribosomal subunit and inhibiting protein synthesis.
    Minocycline hydrochloride