1. Anti-infection
    Metabolic Enzyme/Protease
  2. Bacterial
    Antibiotic
    Phospholipase
  3. Neomycin sulfate

Neomycin sulfate 

Cat. No.: HY-B0470 Purity: >98.0%
Handling Instructions

Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis.

For research use only. We do not sell to patients.

Neomycin sulfate Chemical Structure

Neomycin sulfate Chemical Structure

CAS No. : 1405-10-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 g USD 60 In-stock
Estimated Time of Arrival: December 31
25 g USD 80 In-stock
Estimated Time of Arrival: December 31
50 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 4 publication(s) in Google Scholar

Top Publications Citing Use of Products

View All Phospholipase Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis[1][2].

In Vitro

Neomycin is effective against most gram-negative organisms except Pseudomonas aeruginosa and anaerobic bacteria. Its activity against gram-positive microorganisms is more or less limited to staphylococci, but bacterial resistance supervenes after prolonged use[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

908.88

Formula

C₂₃H₅₂N₆O₂₅S₃

CAS No.

1405-10-3

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 31 mg/mL (34.11 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1003 mL 5.5013 mL 11.0026 mL
5 mM 0.2201 mL 1.1003 mL 2.2005 mL
10 mM 0.1100 mL 0.5501 mL 1.1003 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: >98.0%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

NeomycinBacterialAntibioticPhospholipaseangiogeninproliferationaminoglycosideribosomalproteinsynthesisInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Neomycin sulfate
Cat. No.:
HY-B0470
Quantity:
MCE Japan Authorized Agent: