2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Endonuclease

Endonuclease

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-116770
    PFM01
    		Inhibitor 99.68%
    PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR).
    PFM01
  • HY-145758
    FEN1-IN-SC13
    		Inhibitor 98.89%
    FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor (CN106692155A, SC13).
    FEN1-IN-SC13
  • HY-120951
    PFM39
    		Inhibitor 98.02%
    PFM39, a Mirin analog, is a potent and selective MRE11 exonuclease inhibitor. PFM39 inhibits phosphate rotation for dsDNA exonuclease activity. PFM39 does not inhibit TmMre11 or human MRE11/MRN endonuclease activity.
    PFM39
  • HY-P2863
    Deoxyribonuclease II
    		Inhibitor
    Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research.
    Deoxyribonuclease II
  • HY-148078
    PFM03
    		Inhibitor 98.04%
    PFM03 is a MRE11 Endonuclease inhibitor. PFM03 regulates DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ).
    PFM03
Cat. No. Product Name / Synonyms Application Reactivity