2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-2 Receptor
  6. IL-2R gamma/Common gamma-Chain

IL-2R gamma/Common gamma-Chain

Recombinant Protein Expression Service

IL-2R gamma/Common gamma-Chain

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IL-2R gamma (CD132) is a member of the type I cytokine receptor family, type 5 subfamily. IL-2R gamma is expressed in leucocyte subsets. IL-2R gamma is involved in inflammatory response, and mediates activation of the cells. IL-2R gamma has low-affinity for IL-2, but intermediate affinity for IL-2 when forming heterodimer with IL-2R beta. IL-2R beta/gama heterodimer complex transduces a signal when IL-2 concentrations are relatively high[1]. Human IL-2R gamma consists of extracellular domain (L23-A262), helical domain (V263-L283), and cytoplasmic domain (E284-T369).Human IL-2R gamma shares <75% aa sequence identity with mouse and rats. Rats IL-2R gamma shares 80.70% aa sequence identity with mouse. IL-2R gamma is utilized by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptor, and takes part in the development, activation, proliferation, differentiation and regulation of lymphocytes and other cell types[2].Mutations of L-2R gamm cause human X-linked severe combined immunodeficiency (XSCID)[3].

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Cat. No. Product Name / Synonyms Species Source
  • HY-P70556
    IL-2R gamma/CD132 Protein, Human (HEK293, His)

    IL-2RG; IL-2 R gamma; IL-2Rγ; IL2R γ; Cytokine receptor common subunit gamma; Interleukin-2 receptor subunit gamma; gammaC; P64; CD132 and IL2RG

    		Human HEK293
    IL-2R gamma (CD132), a type I cytokine receptor expressed on leucocyte subsets, is a receptor for IL-2. IL-2R gamma forms heterodimer with IL-2R beta, and increases the affinity of IL-2R beta for IL-2. IL-2R gamma plays an important role in the development, activation, proliferation, differentiation and regulation of lymphocytes and other cell types. IL-2R gamma/CD132 Protein, Human (HEK293, His) is a recombinant human extracellular region of IL-2R gamma (L23-A262) with a C-Terminal 6*His tag, which is produced in HEK293 cells.
  • HY-P74807
    IL-2R gamma/CD132 Protein, Mouse (HEK293, His-Fc)

    Cytokine receptor common subunit gamma; IL-2RG; p64; CD132

    		Mouse HEK293
    IL-2R gamma (CD132), a type I cytokine receptor expressed on leucocyte subsets, is a receptor for IL-2. IL-2R gamma forms heterodimer with IL-2R beta, and increases the affinity of IL-2R beta for IL-2. IL-2R gamma takes part in inflammatory response and mediates activation of the cells . IL-2R gamma plays an important role in the development, activation, proliferation, differentiation and regulation of lymphocytes and other cell types. IL-2R gamma/CD132 Protein, Mouse (HEK293, His-Fc) is a recombinant mice extracellular region of IL-2R gamma (M1-A263) with a C-Terminal hFc and a His tag, which is produced in HEK293 cells.
  • HY-P70693
    IL-2R gamma/CD132 Protein, Mouse (239a.a, HEK293, His)

    IL-2RG; IL-2 R gamma; IL-2Rγ; IL2R γ; Interleukin 2 receptor, gamma chain, isoform CRA_b; Il2rg

    		Mouse HEK293
    IL-2R gamma (CD132), a type I cytokine receptor expressed on leucocyte subsets, is a receptor for IL-2. IL-2R gamma forms heterodimer with IL-2R beta, and increases the affinity of IL-2R beta for IL-2. IL-2R gamma takes part in inflammatory response and mediates activation of the cells . IL-2R gamma plays an important role in the development, activation, proliferation, differentiation and regulation of lymphocytes and other cell types. IL-2R gamma/CD132 Protein, Mouse (239a.a, HEK293, His) is a recombinant mice extracellular region of IL-2R gamma (S25-A263) with a C-Terminal 6*His tag, which is produced in HEK293 cells.
  • HY-P74805
    IL-2R gamma/CD132 Protein, Rat (HEK293, His)

    Cytokine receptor common subunit gamma; IL-2RG; p64; CD132

    		Rat HEK293
    IL-2R gamma (CD132), a type I cytokine receptor expressed on leucocyte subsets, is a receptor for IL-2. IL-2R gamma forms heterodimer with IL-2R beta, and increases the affinity of IL-2R beta for IL-2. IL-2R gamma takes part in inflammatory response and mediates activation of the cells . IL-2R gamma plays an important role in the development, activation, proliferation, differentiation and regulation of lymphocytes and other cell types. IL-2R gamma/CD132 Protein, Rat (HEK293, His) is a recombinant rat extracellular region of IL-2R beta (M1-A262) with a C-Terminal His tag, which is produced in HEK293 cells.
  • HY-P77591
    IL-2R gamma/CD132 Protein, Cynomolgus (HEK293, His)

    CD132; CIDX; IL-2 R gamma; IL2RG; IMD4; P64; SCIDX; SCIDX1; gammaC

    		Cynomolgus HEK293
    IL-2R gamma/CD132 Protein, a common subunit for interleukin receptors, likely collaborates with IL15RA in stimulating neutrophil phagocytosis by IL15. It is shared among IL2, IL4, IL7, IL15, IL21, and possibly IL13 receptors. IL-2R gamma interacts with SHB upon interleukin stimulation and also interacts with IL9. IL-2R gamma/CD132 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-2R gamma/CD132 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-2R gamma/CD132 Protein, Cynomolgus (HEK293, His) is 232 a.a., with molecular weight of 50-68 kDa.
  • HY-P700858
    IL-2R gamma/CD132 Protein, Human (HEK293, hFc)

    CD132; CIDX; IL-2 R gamma; IL2RG; IMD4; P64; SCIDX; SCIDX1; gammaC

    		Human HEK293
    IL-2R gamma/CD132 Protein, a common subunit for interleukin receptors, likely collaborates with IL15RA in stimulating neutrophil phagocytosis by IL15. It is shared among IL2, IL4, IL7, IL15, IL21, and possibly IL13 receptors. IL-2R gamma interacts with SHB upon interleukin stimulation and also interacts with IL9. IL-2R gamma/CD132 Protein, Human (HEK293, hFc) is the recombinant human-derived IL-2R gamma/CD132 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL-2R gamma/CD132 Protein, Human (HEK293, hFc) is 232 a.a., with molecular weight of 70-100 kDa.
  • HY-P77715
    IL-2R beta & IL-2R gamma Heterodimer Protein, Human (HEK293, Fc)

    IL-2RB&IL-2RG; IL-2RG; IL-2R subunit gamma; IL-2R subunit beta; IL-2RB; IL15RB; IL-2 R beta&IL-2 R gamma

    		Human HEK293
    IL-2R beta (CD122) and IL-2Rγ (CD132), type Ⅰ cytokine receptors expressed on T lymphocytes, are receptors for IL-2 (Kd: 1 nM for IL-2R beta approximately). IL-2R beta mediates T cell immune responses. IL-2Rγ mediates inflammatory response
    IL-2Rβ and IL-2Rγ heterodimer binds to IL-2 with intermediate affinity. IL-2R beta & IL-2R gamma Heterodimer Protein, Human (HEK293, Fc) is a recombinant human IL-2R beta (A27-D239) and IL-2R gamma (L23-A262) heterodimer complex, with a C-Terminal hFc tag, which is produced in HEK293 cells.
  • HY-P78083
    IL-2R gamma/CD132 Protein, Human (Biotinylated, HEK293, His-Avi)

    CD132; CIDX; IL-2 R gamma; IL2RG; IMD4; P64; SCIDX; SCIDX1; gammaC

    		Human HEK293
    IL-2R gamma (CD132), a type I cytokine receptor expressed on leucocyte subsets, is a receptor for IL-2. IL-2R gamma forms heterodimer with IL-2R beta, and increases the affinity of IL-2R beta for IL-2. IL-2R gamma plays an important role in the development, activation, proliferation, differentiation and regulation of lymphocytes and other cell types. IL-2R gamma/CD132 Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human extracellular region of IL-2R gamma (L23-N254) with a C-Terminal Avi and a His tag, which is produced in HEK293 cells.
  • HY-P78401
    IL-2R gamma/CD132 Protein, Human (HEK293, His-Avi)

    CD132; CIDX; IL-2 R gamma; IL2RG; IMD4; P64; SCIDX; SCIDX1; gammaC

    		Human HEK293
    IL-2R gamma (CD132), a type I cytokine receptor expressed on leucocyte subsets, is a receptor for IL-2. IL-2R gamma forms heterodimer with IL-2R beta, and increases the affinity of IL-2R beta for IL-2. IL-2R gamma plays an important role in the development, activation, proliferation, differentiation and regulation of lymphocytes and other cell types. IL-2R gamma/CD132 Protein, Human (HEK293, His-Avi) is a recombinant human extracellular region of IL-2R gamma (L23-N254) with a C-Terminal Avi and a His tag, which is produced in HEK293 cells.
  • HY-P74806
    IL-2R gamma/CD132 Protein, Rat (HEK293, hFc)

    Cytokine receptor common subunit gamma; IL-2RG; p64; CD132

    		Rat HEK293
    IL-2R gamma (CD132), a type I cytokine receptor expressed on leucocyte subsets, is a receptor for IL-2. IL-2R gamma forms heterodimer with IL-2R beta, and increases the affinity of IL-2R beta for IL-2. IL-2R gamma takes part in inflammatory response and mediates activation of the cells . IL-2R gamma plays an important role in the development, activation, proliferation, differentiation and regulation of lymphocytes and other cell types. IL-2R gamma/CD132 Protein, Rat (HEK293, hFc) is a recombinant rat extracellular region of IL-2R beta (M1-A262) with a C-Terminal hFc tag, which is produced in HEK293 cells.
Cat. No. Product Name Effect Purity