IGFBP-1
The insulin-like growth factor binding protein (IGFBP) family is a critical component of the insulin-like growth factor (IGF) system that acts as transport proteins, prolongs half-life of IGFs, regulates the clearance of the IGFs, provides a tissue specific localization, and directly modulates IGFs' actions. The IGFBPs comprise a superfamily of six proteins (IGFBP-1-6) that bind to IGFs with high affinity and specificity and a family of IGFBP-related proteins (IGFBP-rPs, since IGFBP-7 to -10), which are structurally similar to the IGFBPs but bind IGFs with much lower affinity. In addition, the effects of IGFBPs on IGFs are regulated in part by IGFBP proteases. Thus, as far as IGF action is concerned, IGFBP proteases may also be regarded as part of the IGF family because they indirectly regulate the action of IGFs
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IGFBP-1 Recombinant Proteins (4)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
