LAMP3/CD63
CD63 is a tetraspanin-family protein concentrated in late endosomes and lysosomes, and its recruitment to the plasma membrane upon platelet or basophil activation made it one of the earliest basophil activation markers. The protein traverses the membrane four times and carries a CCG palmitoylation motif characteristic of the tetraspanin web, where it associates with integrins and with P-selectin in platelets. CD63 is highly enriched on exosomes, underpinning its use as an exosome marker in extracellular vesicle research. CD63 mislocalization characterizes Hermansky-Pudlak syndrome type 2 caused by AP-3 complex defects, and the molecule is also detected in melanoma cells.
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LAMP3/CD63 Recombinant Proteins (7)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
