1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Neurotrophic Factors

Neurotrophic factors (NTFs) are endogenous substances that control neurite outgrowth, neuronal cell differentiation, and survival. Most NTFs belong to one of three families: NGF family (also known as neurotrophins or NTs), the glial cell line–derived neurotrophic factor (GDNF) family ligands (GFLs), and neuropoietic cytokines. Additionally, MANF/CDNF is a novel evolutionarily conserved neurotrophic factor family initially discovered by their neuroprotective activities in dopaminergic neurons. NTFs play important roles in both developments, where they can act as guidance cues for developing neurons, and in the mature nervous system, where they are involved in neuronal survival, synaptic plasticity and the formation of long-lasting memories. They have important roles also in non-neuronal tissues, and regulate, e.g., angiogenesis, kidney development, and spermatogenesis.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7118
    TGF beta 1/TGFB1 Protein, Human (CHO)

    TGF-beta-1; TGFB1; TGFB; rHuTGF-β1

    Human CHO
    TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. TGF beta 1/TGFB1 Protein, Human is a recombinant protein (A279-S390) produced by CHO cells.
  • HY-P70543
    TGF beta 1/TGFB1 Protein, Human (112a.a, HEK293)

    Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1

    Human HEK293
    TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. TGF beta 1/TGFB1 Protein, Human (112a.a, HEK293) is a recombinant protein (A279-S390) produced by HEK293 cells.
  • HY-P7044
    IL-6 Protein, Human

    rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    Human E. coli
    IL-6 Protein, Human is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.
  • HY-P70648
    TGF beta 1/TGFB1 Protein, Mouse/Rat (HEK293)

    TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta

    Rat; Mouse HEK293
    TGF beta 1/TGFB1 Protein, Mouse/Rat (HEK293), is a recombinant cytokine produced in HEK293 cells, is implicated as a key regulator of the development and cyclic remodelling characteristic of reproductive tissues.
  • HY-P7044A
    IL-6 Protein, Human (CHO)

    rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    Human CHO
    IL-6 Protein, Human (CHO) is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.
  • HY-P73276
    LIF Protein, Human (HEK293)

    LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI

    Human HEK293
    LIF protein induces terminal differentiation in leukemic cells, promoting hematopoietic and neuronal cell differentiation, and stimulating acute-phase protein synthesis in hepatocytes. Its diverse activities highlight its role in influencing cellular differentiation across various cell types and physiological contexts. LIF Protein, Human (HEK293) is the recombinant human-derived LIF protein, expressed by HEK293 , with tag free.
  • HY-P73279
    LIF Protein, Mouse (HEK293)

    LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI

    Mouse HEK293
    LIF (Leukemia Inhibitory Factor) prompts terminal differentiation in leukemic cells, inducing hematopoietic and neuronal cell differentiation. It also stimulates acute-phase protein synthesis in hepatocytes. LIF's multifaceted role underscores its significance in regulating hematopoiesis, neurogenesis, and hepatic responses. LIF Protein, Mouse (HEK293) is the recombinant mouse-derived LIF protein, expressed by HEK293 , with tag free. The total length of LIF Protein, Mouse (HEK293) is 180 a.a., with molecular weight of ~35.6 kDa.
  • HY-P7205
    IL-1 beta Protein, Human (CHO)

    rHuIL-1β; Catabolin; IL1F2; IL1B

    Human CHO
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions.  IL-1 beta Protein, Human (CHO) is produced in  CHO cells, and consists of 153 amino acids (A117-S269).
  • HY-P70426G
    GMP TNF-alpha/TNFSF2 Protein, Human

    Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; TNF; TNFA; TNFSF2

    Human E. coli
    Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. GMP TNF-alpha/TNFSF2 Protein, Human is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.
  • HY-P70571
    TNF-alpha/TNFSF2 Protein, Mouse (147a.a)

    Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Soluble Form; Tnf; Tnfa; Tnfsf2

    Mouse E. coli
    Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury.TNF-alpha/TNFSF2 Protein, Mouse (147a.a) is a recombinant protein consisting of 147 amino acids (D89-L235) and is produced in E. coli.
  • HY-P7073A
    IL-1 beta Protein, Mouse (CHO)

    rMuIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B

    Mouse CHO
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions.  IL-1 beta Protein, Mouse (CHO) is produced in  CHO cells, and consists of 152 amino acids (V118-S269).
  • HY-P7119
    TGF beta 2/TGFB2 Protein, Human

    TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2

    Human HEK293
    Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Human is produced in HEK293 cells, and consists of 112 amino acids (A303-S414).
  • HY-P7660
    Beta-NGF Protein, Human (HEK293)

    rHuBeta-NGF; Beta-Nerve Growth Factor; Beta-NGF;

    Human HEK293
    Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Beta-NGF Protein, Human (HEK293) is produced by HEK293 cells (S122-R239), with tag free.
  • HY-P7044G
    GMP IL-6 Protein, Human

    Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2

    Human E. coli
    IL-6 protein is a multifunctional cytokine that plays multiple biological functions in immunity, tissue regeneration, and metabolism. After binding to IL6R, the resulting complex binds to the signaling subunit IL6ST/gp130, triggering the intracellular IL6 signaling pathway. GMP IL-6 Protein, Human is the recombinant human-derived IL-6 protein, expressed by E. coli , with tag free. GMP IL-6 Protein, Human, has molecular weight of ~20.0 kDa.
  • HY-P7378
    IL-6 Protein, Mouse (CHO, His)

    rMuIL-6, His; B cell differentiation factor; IL6

    Mouse CHO
    IL-6 Protein, Mouse (CHO, His) is a multifunctional cytokine that can regulate various immune and inflammatory responses.
  • HY-P77945
    GDF-15 Protein, Mouse (HEK293, Fc)

    GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta

    Mouse HEK293
    Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor β (TGF-β) superfamily. GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1), placental transforming growth factor-β (PTGFB), prostate-derived factor (PDF), and placental bone morphogenetic protein (PLAB). GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging, cancer, and metabolic processes. GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET, AKT, ERK1/2, and phospholipase C (PLCγ). GDF-15 Protein, Mouse (HEK293, Fc) has 115 amino acids expressed by HEK293 cells with N-terminal hFc tag.
  • HY-P73145
    IL-1 alpha Protein, Human (HEK293)

    IL-1α; Hematopoietin-1; IL1A; IL1F1; IL-1 alpha

    Human HEK293
    IL-1 alpha is a ubiquitous and pivotal pro-inflammatory cytokine. IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha plays an important role in inflammation and bridges the innate and adaptive immune systems. IL-1 alpha mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. IL-1 alpha protein, Human (HEK293) is a recombinant protein consisting of 159 amino acids (S113-A271) and is produced by HEK293 cells.
  • HY-P73149
    IL-1 beta Protein, Human (E6K, His)

    Interleukin-1 beta; IL-1β; IL1F2; IL-1 beta; IL1B

    Human E. coli
    IL-1 beta is a potent proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta plays a key role in inflammation and immunologic reactions.  IL-1 beta Protein, Human (E6K, His) is produced in  E. coli with a N-Terminal His-tag. It consists of 269 amino acids (M1-S269).
  • HY-P70236
    Latent TGF beta 1/TGFB1 Protein, Human (C33S, HEK293, His)

    rHuLatent TGF Beta-1-C33S, His; Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB

    Human HEK293
    Latent TGF beta 1/TGFB1 Protein is a large extracellular matrix protein and an associated ligand of fibrillinmicrofibrils. Latent TGF beta 1/TGFB1 Protein, Human (C33S, HEK293, His) is a recombinant Biotinylated protein (L30-S390) produced by HEK293 cells with His tag.
  • HY-P70433
    TGF beta 1/TGFB1 LAP Protein, Human (HEK293)

    Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB

    Human HEK293
    TGF beta 1/TGFB1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. TGF beta 1 is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, apoptosis, and can regulate the expression and activation of other growth factors, including interferon gamma and tumor necrosis factor alpha. TGF beta 1/TGFB1 LAP Protein, Human (HEK293) is the recombinant human-derived TGF beta 1/TGFB1 LAP protein, expressed by HEK293 , with tag free. and C33S mutation.
Cat. No. Product Name Effect Purity