2. Recombinant Proteins
  3. CD Antigens
  4. Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins
  5. IREM-1/CD300f

IREM-1/CD300f

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72892
    CD31/PECAM-1 Protein, Human

    Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; PECA1; CD31

    		Human HEK293
    CD31/PECAM-1 Protein, a pivotal cell adhesion molecule, is essential for leukocyte transendothelial migration (TEM) in most inflammatory conditions. PECAM1 modulates bradykinin receptor BDKRB2 activation and regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells. Signaling through PECAM-1 leads to the activation of neutrophils, monocytes and leukocytes. CD31/PECAM-1 Protein, Human is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with tag free. The total length of CD31/PECAM-1 Protein, Human is 574 a.a., with molecular weight of ~115 kDa.
  • HY-P71595
    CD300LF Protein, Human (His)

    CD300 antigen like family member; CD300 antigen-like family member F; CD300 molecule like family member f; CD300f; CD300LF; CLM; CLM-1; CLM1; CMRF35-like molecule 1; IGSF; IgSF13; Inhibitory receptor IREM1; IREM; IREM-1; IREM1; Nepmucin; NK inhibitory receptor; NKIR; TREM

    		Human E. coli
    CD300LF Protein functions as a versatile immune regulator, acting as an inhibitory receptor for myeloid and mast cells. It plays a crucial role in immune homeostasis by positively regulating apoptotic cell phagocytosis through binding to phosphatidylserine. CD300LF also acts as a negative regulator of mast cell activation and allergic responses by binding to ceramide and sphingomyelin. It may enhance IL-4 and IL-13 signaling and negatively regulates TLR signaling. Additionally, CD300LF inhibits osteoclast formation and induces macrophage cell death. CD300LF Protein, Human (His) is the recombinant human-derived CD300LF protein, expressed by E. coli, with N-6*His labeled tag. The total length of CD300LF Protein, Human (His) is 137 a.a., with molecular weight of ~21 kDa.
  • HY-P72490
    CD31/PECAM-1 Protein, Human (HEK293, His)

    Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA; PECA1; CD31; PECAM1  

    		Human HEK293
    CD31/PECAM-1 Protein is a cell-cell adhesion protein that is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. CD31/PECAM-1 Protein, Human (HEK293, His) is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD31/PECAM-1 Protein, Human (HEK293, His) is 574 a.a., with molecular weight of 75-110 kDa.
  • HY-P72737
    CD31/PECAM-1 Protein, Mouse (573a.a, HEK293, His)

    Platelet endothelial cell adhesion molecule; PECAM-1; CD31; Pecam

    		Mouse HEK293
    The CD31/PECAM-1 protein is a cell adhesion molecule critical for leukocyte transendothelial migration (TEM) under inflammatory conditions. CD31/PECAM-1 also regulates bradykinin receptor BDKRB2 activation and modulates ERK1/2 activation in endothelial cells. CD31/PECAM-1 Protein, Mouse (573a.a, HEK293, His) is the recombinant mouse-derived CD31/PECAM-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD31/PECAM-1 Protein, Mouse (573a.a, HEK293, His) is 573 a.a., with molecular weight of approximately 86-106 kDa.
  • HY-P76793
    CD300LF Protein, Mouse (HEK293, Fc)

    CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; CD300f

    		Mouse HEK293
    CD300LF protein, also known as DEC-205/CD205, directs antigens to an antigen-processing compartment. It inhibits myeloid and mast cells, promoting phagocytosis of apoptotic cells. It maintains immune homeostasis by enhancing macrophage-mediated efferocytosis and inhibiting dendritic cell-mediated efferocytosis. It binds to ceramide ligands, regulating mast cell activation and allergic responses. It enhances IL-4 and IL-13 signaling and inhibits Toll-like receptor signaling and osteoclast formation. It induces macrophage cell death, acts as a receptor for murine norovirus, and determines viral tropism. CD300LF Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD300LF protein, expressed by HEK293, with C-mFc labeled tag. The total length of CD300LF Protein, Mouse (HEK293, Fc) is 174 a.a., with molecular weight of ~45.3 KDa.
  • HY-P70988
    CD31/PECAM-1 Protein, Human (HEK293, Fc)

    Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA; PECA1; CD31; PECAM1

    		Human HEK293
    CD31/PECAM-1 is a cell-cell adhesion protein. CD31/PECAM-1 regulates the activation of the slow hormone receptor BDKRB2 in endothelial cells and the activation of ERK1/2 induced by hypertonic shock and induces susceptibility to atherosclerosis. CD31/PECAM-1 mediates adhesion to endothelial cells and regulates tumor growth by forming new endothelial cell tubes. CD31/PECAM-1 Protein, Human (HEK293, Fc) is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD31/PECAM-1 Protein, Human (HEK293, Fc) is 574 a.a., with molecular weight of 110-130 kDa.
  • HY-P71561
    CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO)

    Cd300lf; Clm1CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; CD antigen CD300f

    		Rat E. coli
    CMRF35-like molecule 1 (CLM-1) Protein serves as an inhibitory receptor for myeloid and mast cells, crucial in immune homeostasis by regulating various immune responses. CLM-1 positively modulates macrophage-mediated efferocytosis by recognizing phosphatidylserine on apoptotic cells. It inhibits dendritic cell-mediated efferocytosis and Fc epsilon receptor-dependent mast cell activation. CLM-1 may act as a coreceptor for IL-4, enhancing IL-4- and IL-13-induced signaling. Additionally, it negatively regulates TLR signaling and inhibits osteoclast formation while inducing macrophage cell death. The protein interacts with PTPN6/SHP-1 and associates with IL4R. CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO) is the recombinant rat-derived CMRF35-like molecule 1 protein, expressed by E. coli, with N-His, C-Myc, N-SUMO labeled tag. The total length of CMRF35-like molecule 1 Protein, Rat (Myc, His-SUMO) is 163 a.a., with molecular weight of ~38.3 kDa.
Cat. No. Product Name Effect Purity