1. Screening Libraries
  2. CNS-Penetrant Compound Library

CNS-Penetrant Compound Library

Cat. No.: HY-L028
Library Contents: XLSX PDF

A unique collection of 321 bioactive CNS-penetrant compounds for high throughput screening (HTS) and high content screening (HCS).

Size (Pre-dissolved DMSO or Solid) Price Stock
30 μL/well (10 mM solution) Get quote In-stock
50 μL/well (10 mM solution) Get quote In-stock
100 μL/well (10 mM solution) Get quote In-stock
250 μL/well (10 mM solution) Get quote In-stock

Please contact us at

[email protected]

Top Publications Citing Use of Products

MCE Screening Library Partners

  • Description

  • Product Details

  • Composition

  • Contents

  • Documentation

Description
& Advantages

•   A unique collection of 321 bioactive CNS-penetrant compounds for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as Kinases, GPCR and Ion Channels, and more.

•   A useful tool for the discovery of drugs used for brain diseases, such as brain tumors, mental disorders, and neurodegenerative diseases.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some inhibitors have been approved by FDA.

•   Structurally diverse, medicinally active, CNS-penetrant and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 321 CNS-penetrant compounds supplied as pre-dissolved DMSO solutions or Solid
Container:
96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

CNS-Penetrant Compound Library

Source: MedChem Express

Contents of CNS-Penetrant Compound Library

Plate layout: HY-L028-1

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Pimavanserin tartrate D-Cycloserine L-Cycloserine Vinorelbine (ditartrate) Cyclosporin A Pyrazinamide Cisatracurium (besylate) Flucytosine Vigabatrin Vitamin B12 Empty
b Empty Isoniazid Salicylic acid Tramiprosate Choline (chloride) Ethosuximide Trimethadione Dimethyl fumarate Valproic acid Penicillamine Tranexamic acid Empty
c Empty Acetylcysteine Metformin (hydrochloride) Ethionamide 5-Aminolevulinic acid (hydrochloride) Chlorzoxazone Levetiracetam Metronidazole Gabapentin Edaravone Fosfomycin (calcium) Empty
d Empty Theophylline Aspirin Tranylcypromine (hemisulfate) Sodium phenylbutyrate Amantadine (hydrochloride) Antipyrine Temozolomide Halothane Acamprosate (calcium) 4-Aminoantipyrine Empty
e Empty Ibuprofen (R)-(-)-Ibuprofen RJR-2403 (hemioxalate) Zonisamide Memantine (hydrochloride) Primidone Metaxalone Acetazolamide Stavudine Acyclovir Empty
f Empty Lamivudine Melatonin Lomustine Riluzole Phenelzine (sulfate) Lidocaine Didanosine Carbamazepine Dexmedetomidine (hydrochloride) Rufinamide Empty
g Empty Felbamate Methocarbamol Cytarabine Ribavirin (R)-Flurbiprofen Flurbiprofen Veliparib Etomidate Busulfan Emtricitabine Empty
h Empty Pyrimethamine Rivastigmine Oxcarbazepine Phenytoin Sulfamethoxazole Daidzein S-(+)-Ketoprofen Ketoprofen Ganciclovir Miglustat (hydrochloride) Empty

Plate layout: HY-L028-2

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Lamotrigine sn-Glycero-3-phosphocholine Procarbazine (Hydrochloride) Thalidomide Salsalate Lenalidomide Ramelteon Pyridostigmine (bromide) Vorinostat Mirtazapine Empty
b Empty Nevirapine Atenolol Clonidine (hydrochloride) Zidovudine Adenosine Rasagiline (mesylate) Diethylstilbestrol Genistein Lidocaine (hydrochloride) Tolcapone Empty
c Empty Pomalidomide Phenytoin (sodium) Rolipram Bupropion (hydrochloride) Sulfamethoxypyridazine Etomidate (hydrochloride) Guanfacine (hydrochloride) Milnacipran ((1S-cis) hydrochloride) Milnacipran (hydrochloride) Pramipexole (dihydrochloride) Empty
d Empty Oseltamivir (acid) Probenecid Cladribine Abacavir Tenofovir Galanthamine Etodolac Zolmitriptan Terbinafine BSI-201 Empty
e Empty Propranolol (hydrochloride) Diclofenac Disulfiram Ropinirole (hydrochloride) Metoclopramide Protriptyline (hydrochloride) Nortriptyline (hydrochloride) Retinoic acid Desipramine hydrochloride Chlorambucil Empty
f Empty Clioquinol Fluconazole Fingolimod Phenylbutazone Cyclobenzaprine (hydrochloride) Olanzapine Molindone (hydrochloride) Amoxapine Venlafaxine (hydrochloride) Amitriptyline (hydrochloride) Empty
g Empty Rofecoxib Progesterone Rotigotine Efavirenz Pregnenolone Imipramine (hydrochloride) Tetrabenazine Diclofenac (Sodium) Cytosporone B Cyproheptadine (hydrochloride) Empty
h Empty Quinidine Dyclonine (hydrochloride) Clozapine Loxapine Piroxicam Palonosetron (Hydrochloride) Trihexyphenidyl (hydrochloride) Topiramate Liproxstatin-1 Sulpiride Empty

Plate layout: HY-L028-3

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Sertraline (hydrochloride) Fingolimod (hydrochloride) Testosterone (propionate) Fluoxetine (hydrochloride) L-779450 Granisetron (Hydrochloride) Voriconazole Clomipramine (hydrochloride) Meloxicam Roscovitine Empty
b Empty Sulindac Laquinimod Rosiglitazone Oxybutynin Indomethacin Prednisone Capecitabine Prednisolone Ofloxacin Levofloxacin Empty
c Empty L-701324 SC79 NS 1738 SRI-011381 (hydrochloride) MRK-016 SB 239063 Tamoxifen Naratriptan (hydrochloride) Methylprednisolone Gatifloxacin Empty
d Empty Haloperidol Ketorolac (tromethamine salt) Naltrexone (Hydrochloride) Droperidol SB-222200 SNS-032 GTS-21 (dihydrochloride) Loratadine Quetiapine Amoxicillin (sodium) Empty
e Empty Doxylamine (succinate) SB-269970 (hydrochloride) Alfuzosin Rizatriptan (benzoate) Dexamethasone Erlotinib Bendamustine (hydrochloride) Sulfasalazine Sunitinib Desvenlafaxine (succinate hydrate) Empty
f Empty Dantrolene (sodium hemiheptahydrate) Rivastigmine (tartrate) Flavopiridol Prednisolone (21-acetate) Benztropine (mesylate) Perphenazine Lovastatin Fosphenytoin (disodium) NGP555 Thioridazine (hydrochloride) Empty
g Empty Trazodone (hydrochloride) Trimipramine (maleate) PQR309 Tiagabine (hydrochloride) Sumatriptan (succinate) Escitalopram (oxalate) GNE-317 Mefloquine (hydrochloride) Nimodipine Simvastatin Empty
h Empty Amoxicillin (trihydrate) Vatalanib (dihydrochloride) Vismodegib Buspirone (hydrochloride) Trimethobenzamide hydrochloride Domperidone Paliperidone Iloperidone Erlotinib (Hydrochloride) Fluvoxamine (maleate) Empty

Plate layout: HY-L028-4

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Olaparib Dexamethasone (acetate) Aztreonam AK-7 Pazopanib Flavopiridol (Hydrochloride) Candesartan AEE788 Vilazodone Debio 0932 Empty
b Empty Gefitinib Hydroxyzine (dihydrochloride) Aripiprazole Cediranib SB-590885 Methotrexate (+)-JQ-1 Selumetinib Topotecan (Hydrochloride) AZD3759 Empty
c Empty Orphenadrine (citrate) Sorafenib LP-211 Ziprasidone (hydrochloride monohydrate) Almotriptan (malate) Dacomitinib Pazopanib (Hydrochloride) Vandetanib Cefotaxime (sodium salt) Miconazole (nitrate) Empty
d Empty Trifluoperazine (dihydrochloride) Palbociclib (hydrochloride) Dasatinib Glibenclamide Firategrast Amprenavir Nefazodone (hydrochloride) Epothilone B Fluphenazine (dihydrochloride) Enzastaurin Empty
e Empty Nicardipine (Hydrochloride) Pemetrexed (disodium hemipenta hydrate) Probucol Vardenafil (hydrochloride) Aprepitant Conivaptan (hydrochloride) Piperacillin (sodium) Ceftazidime Delavirdine (mesylate) VER-155008 Empty
f Empty Mezlocillin (sodium) Tandutinib Tamoxifen (Citrate) Cefepime (Dihydrochloride Monohydrate) Palbociclib (isethionate) Atorvastatin (hemicalcium salt) Epirubicin (hydrochloride) Lapatinib Irinotecan Cilengitide Empty
g Empty Imatinib (Mesylate) Hoechst 34580 (tetrahydrochloride) Ceftriaxone (sodium salt) Candesartan (Cilexetil) Trametinib GNE-7915 (tosylate) Lopinavir Sorafenib (Tosylate) Lonafarnib Abacavir (sulfate) Empty
h Empty Irinotecan (hydrochloride trihydrate) Dihydroergotamine (mesylate) Itraconazole Ritonavir Streptomycin (sulfate) Hydroxyurea Atazanavir (sulfate) Rifampicin Cabazitaxel Vincristine (sulfate) Empty

Plate layout: HY-L028-5

1 2 3 4 5 6 7 8 9 10 11 12
a Empty Lapatinib (ditosylate) Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
b Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
c Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
d Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
e Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
f Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
g Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
h Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty Empty
Documentation

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
CNS-Penetrant Compound Library
Cat. No.:
HY-L028
Quantity:

Request SDF File

Please enter your email address. We will send your requested SDF file to you as soon as possible.