Cathepsin W
Cathepsin W (CTSW), historically named lymphopain, is a papain-family cysteine protease whose expression is largely confined to cells of the cytotoxic lymphocyte lineage, most prominently natural killer cells and CD8-positive cytotoxic T cells. Transcripts are weak or absent from most other tissues, making CTSW one of the most lineage-restricted cathepsin genes. The enzyme is predicted to follow the standard preproenzyme maturation pathway, yet its physiological substrates and activation partners remain undefined, and mouse knockout studies have not revealed striking phenotypes. Proposed functions center on cytotoxic lymphocyte biology, and CTSW expression has served as a marker of NK cell activity in immunological analyses.
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Cathepsin W Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
