Complement Factor H Related 3
Complement factor H-related protein 3 (CFHR3) is a five-domain member of the FHR family that binds C3b and C3d as well as apoptotic cells, C-reactive protein, and heparin. In contrast to several relatives, CFHR3 appears to dampen complement activation and to possess anti-inflammatory properties, and it competes with factor H for ligand binding in a manner that modulates rather than abolishes regulation. The common CFHR1-CFHR3 deletion affects circulating levels of both proteins and has been associated with autoimmune conditions such as lupus nephritis as well as protection from typical hemolytic uremic syndrome.
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Complement Factor H Related 3 Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
