1. Recombinant Proteins
  2. CD Antigens
  3. B Cell CD Proteins

The cluster of differentiation (CD) antigens a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. The B-cell precursors express cytoplasmic CD22 and CD79 in early, while surface CD19 and CD10 appear later. With increased differentiation there is gradual decrease in CD10 and gradual gain in CD20. CD10, however, appears again in follicular center cells (FCCs) in the lymph nodes and the spleen. Normal mature B cells express surface immunoglobulin as well as CD19, CD20, and CD22.

Cat. No. Product Name / Synonyms Species Source
  • HY-P70731
    CD38 Protein, Human (HEK293, His)

    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule; CD38

    Human HEK293
    The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (HEK293, His) is the recombinant human-derived CD38 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD38 Protein, Human (HEK293, His) is 258 a.a., with molecular weight of 38-50 kDa.
  • HY-P7374
    IL-2R alpha/CD25 Protein, Human (HEK293, Fc)

    rHuIL-2R α/CD25, Fc Chimera; TAC antigen; IL-2-RA; IL-2 R alpha; IL-2Rα; IL2RA

    Human HEK293
    IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (HEK293, Fc) is a recombinant human IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).
  • HY-P7003
    BAFF/TNFSF13B Protein, Human (CHO)

    rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20

    Human CHO
    BAFF/TNFSF13B Protein, Human (CHO) is a member of the tumor necrosis factor (TNF) superfamily, and plays an essential role in peripheral B-cell homeostasis.
  • HY-P7168
    Fas/CD95 Protein, Human (HEK293)

    rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; FAS1; Apo-1

    Human HEK293
    Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293) has a full length of 157 amino acids (Q26-S172), produced in HEK293 cells with tag free.
  • HY-P70428
    BAFF/TNFSF13B Protein, Human (HEK293, His)

    Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1

    Human HEK293
    BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury. Human BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. BAFF/TNFSF13B Protein, Human (HEK293, His) is the extracullar part of BAFF protein (A134-L285), produced in HEK293 cells with N-terminal 6*His-tag.
  • HY-P70651
    B7-1/CD80 Protein, Human (208a.a, HEK293, His)

    CD80; Activation B7-1 antigen; B7; BB1; CD28LG1; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80

    Human HEK293
    The CD80 protein plays a key role in T lymphocyte activation, promoting proliferation and cytokine production through CD28 binding. In contrast, interaction with CTLA-4 inhibits T cell activation. B7-1/CD80 Protein, Human (208a.a, HEK293, His) is the recombinant human-derived B7-1/CD80 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B7-1/CD80 Protein, Human (208a.a, HEK293, His) is 208 a.a., with molecular weight of 38-60 kDa.
  • HY-P70720
    CD24 Protein, Human (S44T, HEK293, Fc)

    Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A

    Human HEK293
    CD24 protein plays a pivotal role in cell differentiation across various cell types, with signaling potentially initiated by lectin-like ligand binding to CD24 carbohydrates, transduced through second messengers released from the GPI-anchor. CD24 also modulates B-cell activation responses, promoting AG-dependent B-cell proliferation and preventing terminal differentiation into antibody-forming cells. In association with SIGLEC10, CD24 contributes to the selective suppression of the immune response to DAMPs such as HMGB1, HSP70, and HSP90, suggesting a role in immune regulation. Additionally, CD24 is implicated in controlling autoimmunity, exhibiting cell-type-specific interactions with LYN and FGR in diverse cellular processes and immune regulation. CD24 Protein, Human (S44T, HEK293, Fc) is the recombinant human-derived CD24 protein, expressed by HEK293 , with C-hFc labeled tag and S44T mutation. The total length of CD24 Protein, Human (S44T, HEK293, Fc) is 33 a.a., with molecular weight of 40-55 kDa.
  • HY-P72019
    Siglec-2/CD22 Protein, Human (HEK293, His)

    B-cell receptor CD22; BL-CAM; Siglec-2; CD22; SIGLEC2

    Human HEK293
    The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-2/CD22 Protein, Human (HEK293, His) is 668 a.a., with molecular weight of 77-110 kDa.
  • HY-P7215
    IL-2R alpha/CD25 Protein, Human (HEK293, N-His)

    rHuIL-2Rα, His; TAC-antigen; CD25

    Human HEK293
    IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (HEK293, N-His) is a recombinant human IL-2R alpha protein with a His tag at the N-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).
  • HY-P72353
    CD28 Protein, Human/Cynomolgus (Biotinylated, HEK293, Fc-Avi)

    CD28; CD28 antigen; CD28 molecule; T-cell-specific surface glycoprotein CD28; Tp44; TP44

    Human; Cynomolgus HEK293
    The CD28 protein is critical for T cell activation, enhancing proliferation, cytokine production, and survival. When linked to TCR/CD3 and CD40L, CD28 promotes the production of IL4 and IL10, thereby regulating immune responses. CD28 Protein, Human/Cynomolgus (Biotinylated, HEK293, Fc-Avi) is the recombinant human, cynomolgus-derived CD28 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of CD28 Protein, Human/Cynomolgus (Biotinylated, HEK293, Fc-Avi) is 134 a.a., with molecular weight of 60-90 kDa.
  • HY-P72356
    CD38 Protein, Human (Biotinylated, HEK293, His-Avi)

    ADP-ribosyl cyclase1; 2'-phospho-ADP-ribosyl cyclase; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1

    Human HEK293
    The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD38 protein, expressed by HEK293 , with N-Avi, N-6*His labeled tag. The total length of CD38 Protein, Human (Biotinylated, HEK293, His-Avi) is 258 a.a., with molecular weight of 40-50 kDa.
  • HY-P72847
    BCMA/TNFRSF17 Protein, Human (HEK293, His)

    Tumor necrosis factor receptor superfamily member 17; CD269; TNFRSF17; BCM; BCMA

    Human HEK293
    B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Human (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 54 amino acids (M1-A54) and is produced in HEK293 cells.
  • HY-P72890
    CD21 Protein, Human (HEK293, His)

    Complement receptor type 2; Cr2; EBV receptor; CD21; C3DR

    Human HEK293
    CD21 Protein, a receptor for complement C3, Epstein-Barr virus, and HNRNPU, activates B lymphocytes and aids Epstein-Barr virus entry in microbial infection. Its engagement with these ligands highlights its vital role in immune responses and interactions, regulating B-cell activation and host defense against infections. CD21 Protein, Human (HEK293, His) is the recombinant human-derived CD21 protein, expressed by HEK293 , with C-His, C-10*His labeled tag. The total length of CD21 Protein, Human (HEK293, His) is 951 a.a., with molecular weight of 110-120 kDa.
  • HY-P72920
    CD5 Protein, Human (HEK293, His)

    T-cell surface glycoprotein CD5; Ly-1; Lyt-1; CD5; Leu-1

    Human HEK293
    The CD5 protein is a potential receptor that regulates T cell proliferation. Its interactions with CD72/LYB-2 and PTPN6/SHP-1 indicate multifaceted roles in cellular processes, serving as key mediators of T cell responses. CD5 Protein, Human (HEK293, His) is the recombinant human-derived CD5 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD5 Protein, Human (HEK293, His) is 348 a.a., with molecular weight of ~48.9 kDa.
  • HY-P7321
    B7-1/CD80 Protein, Human (HEK293, Fc)

    rHuB7-1/CD80, Fc Chimera; BB1; CD28LG; CD28LG1; LAB7

    Human HEK293
    B7-1/CD80 Protein, Human (HEK293, Fc) is a polypeptide chain with the C-termimal human IgG1 Fc fragment produced in HEK293 cells. CD80 is a costimulatory molecule known for its role in T-cell activation and also in regulating normal and malignant B cellsactivity.
  • HY-P74330
    CD19 Protein, Human (HEK293, His)

    B-lymphocyte antigen CD19; CD19; B-lymphocyte surface antigen B4

    Human HEK293
    The CD19 protein is a B cell antigen receptor coreceptor that enhances downstream signaling pathways, lowers the activation threshold, and helps B cells respond to antigens. It activates phosphatidylinositol 3-kinase and mobilizes intracellular Ca(2+). CD19 Protein, Human (HEK293, His) is the recombinant human-derived CD19 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD19 Protein, Human (HEK293, His) is 291 a.a., with molecular weight of ~47 kDa.
  • HY-P77714
    IL-21R Protein, Human (217a.a, HEK293, Fc)

    IL-21 receptor; IL-21R; CD360; NILR

    Human HEK293
    IL-21R protein, a receptor for interleukin-21, forms a heterodimer with the common gamma subunit and associates with Janus kinase 1 (JAK1). These interactions are pivotal for transducing the cellular responses initiated by interleukin-21, regulating immune processes and inflammatory pathways. IL-21R Protein, Human (217a.a, HEK293, Fc) is the recombinant human-derived IL-21R protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL-21R Protein, Human (217a.a, HEK293, Fc) is 217 a.a., with molecular weight of 60-70 kDa.
  • HY-P77851
    Syndecan-1/CD138 Protein, Human (HEK293, Fc)

    Syndecan-1; SYND1; CD138; SDC1; SDC; SDC1

    Human HEK293
    Syndecan-1/CD138 Protein, a cell surface proteoglycan, connects the cytoskeleton to the interstitial matrix with heparan sulfate and chondroitin sulfate. It regulates exosome biogenesis with SDCBP and PDCD6IP. Syndecan-1/CD138 Protein induces its own expression through an MSX1 pathway in dental cells and interacts with CDCP1 and TIAM1. It also interacts with MDK, participating in diverse cellular processes. Syndecan-1/CD138 Protein, Human (HEK293, Fc) is the recombinant human-derived Syndecan-1/CD138 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Syndecan-1/CD138 Protein, Human (HEK293, Fc) is 232 a.a., with molecular weight of 70-100 kDa.
  • HY-P78063
    B7-1/CD80 Protein, Human (Biotinylated, HEK293, His-Avi)

    CD80 molecule; B7; B71; B7-1; BB1; CD28LG1; CD80; B7.1; CD28LG1; LAB7

    Human HEK293
    The CD80 protein plays a key role in T lymphocyte activation, promoting proliferation and cytokine production through CD28 binding. In contrast, interaction with CTLA-4 inhibits T cell activation. B7-1/CD80 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived B7-1/CD80 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of B7-1/CD80 Protein, Human (Biotinylated, HEK293, His-Avi) is 208 a.a., with molecular weight of 50-70 kDa.
  • HY-P78064
    B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi)

    CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2

    Human HEK293
    B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of B7-2/CD86 Protein, Human (Biotinylated, HEK293, His-Avi) is 222 a.a., with molecular weight of 55-70 kDa.
Cat. No. Product Name Effect Purity