1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Translocases (EC 7)

Enzymes can be classified systematically according to the difference between reaction and substrate specificity, and the mechanism of action. Translocases (EC 7.x.x.x) is a new Enzyme Classification (EC) class that is added to describe those enzymes catalyzing the movement of ions or molecules across membranes or their separation within membranes. Some enzymes that had previously been classified in other classes, such as EC 3.6.3.-, which are involved the hydrolysis of ATP, are included in the EC 7 class nowadays. The subclasses EC 7.1 to EC 7.6 designate the types of ion or molecule translocated (e.g., catalyzingthe translocation of hydrons, inorganic cations and their chelates, inorganic anions, amino acids and peptides, carbohydrates. and their derivatives, other compounds linked to the hydrolysis of a nucleoside triphosphate) .

Cat. No. Product Name / Synonyms Species Source
  • HY-P72094
    ATP2A2 Protein, Human (His)

    Atp2a2; ATP2B; ATPase Ca++ transporting cardiac muscle slow twitch 2; Calcium pump 2; ATPase 2

    Human E. coli
    The ATP2A2 protein is a magnesium-dependent enzyme that hydrolyzes ATP and transfers calcium from the cytoplasm to the sarcoplasmic reticulum. It participates in autophagy during starvation and interacts with VMP1 to achieve ER isolating membrane contact. ATP2A2 Protein, Human (His) is the recombinant human-derived ATP2A2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ATP2A2 Protein, Human (His) is 443 a.a., with molecular weight of ~56 kDa.
  • HY-P72095
    ATP5F1A Protein, Human (His)

    ATP synthase alpha chain; ATP synthase alpha chain; mitochondrial; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit 1; cardiac muscle; ; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform 2; alpha subunit; ATP5A; Atp5a1; ATP5AL2; ATPA_HUMAN; ATPM; hATP1; HEL-S-123m; MC5DN4; mitochondrial;

    Human E. coli
    ATP5F1A is an important component of mitochondrial ATP synthase (complex V) that coordinates ATP production from ADP by utilizing the transmembrane proton gradient. As part of the F-type ATPase, the α and β subunits of ATP5F1A form the catalytic core to achieve ATP hydrolysis. ATP5F1A Protein, Human (His) is the recombinant human-derived ATP5F1A protein, expressed by E. coli , with N-6*His labeled tag. The total length of ATP5F1A Protein, Human (His) is 510 a.a., with molecular weight of ~59.2 kDa.
  • HY-P72098
    ATP5D Protein, Human (His)

    ATP synthase subunit delta; mitochondrial ; ATP synthase subunit delta; mitochondrial; ATP synthase; H+ transporting; mitochondrial F1 complex; delta subunit; ATP5D; ATPD_HUMAN; F ATPase delta subunit ; F-ATPase delta subunit; Mitochondrial ATP synthase complex delta subunit precusor ; Mitochondrial ATP synthase delta subunit

    Human E. coli
    ATP5D Protein, a vital component of mitochondrial membrane ATP synthase (Complex V), facilitates ATP generation from ADP using the proton gradient established by respiratory chain electron transport complexes. As part of the F(1) domain and central stalk, ATP5D contributes to ATP hydrolysis through a rotary mechanism. The ATP synthase complex, involving ATP5D, is pivotal for cellular energy production via ATP synthesis. ATP5D Protein, Human (His) is the recombinant human-derived ATP5D protein, expressed by E. coli , with N-10*His labeled tag. The total length of ATP5D Protein, Human (His) is 146 a.a., with molecular weight of ~20 kDa.
  • HY-P75155
    GRK2 Protein, Human (sf9, His-GST)

    Beta-adrenergic receptor kinase 1; Beta-ARK-1; ADRBK1; BARK; BARK1

    Human Sf9 insect cells
    The GRK2 protein is a highly specific, selective phosphorylation agonist that occupies beta-adrenergic receptors and related receptors, inducing desensitization and serving as an important regulatory mechanism. In addition to G protein-coupled receptor desensitization, GRK2 actively regulates the ciliary smoothing (SMO)-dependent Hedgehog (Hh) pathway by promoting SMO transport and enhancing SMO activity. GRK2 Protein, Human (sf9, His-GST) is the recombinant human-derived GRK2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of GRK2 Protein, Human (sf9, His-GST) is 689 a.a., with molecular weight of ~110 kDa.
  • HY-P71550
    ATP5MG Protein, Bovine (Myc, His)

    ATP5MG; ATP5LATP synthase subunit g; mitochondrial; ATPase subunit g; ATP synthase membrane subunit g

    Bovine E. coli
    ATP5MG Protein, an essential part of mitochondrial membrane ATP synthase (Complex V), facilitates ATP generation from ADP using the proton gradient established by respiratory chain electron transport complexes. Positioned within the F(0) domain as a minor subunit alongside subunit a, ATP5MG collaborates with various subunits in the overall F-type ATPase complex, including CF(1) and CF(0), to ensure efficient ATP synthesis. ATP5MG Protein, Bovine (Myc, His) is the recombinant bovine-derived ATP5MG protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of ATP5MG Protein, Bovine (Myc, His) is 102 a.a., with molecular weight of ~18.7 kDa.
  • HY-P71716
    ATP5F1B Protein, Human (P.pastoris, His)

    ATP 5B; ATP synthase H+ transporting mitochondrial F1 complex beta polypeptide; ATPB; ATPB_HUMAN; ATPMB; ATPSB

    Human P. pastoris
    ATP5F1B protein is an important component of mitochondrial membrane ATP synthase (complex V). ATP5F1B Protein, Human (P.pastoris, His) is the recombinant human-derived ATP5F1B protein, expressed by P. pastoris , with N-His labeled tag. The total length of ATP5F1B Protein, Human (P.pastoris, His) is 482 a.a., with molecular weight of ~53.8 kDa.
  • HY-P72096
    ATP5F1A Protein, Human (His-SUMO)

    ATP synthase alpha chain; ATP synthase alpha chain; mitochondrial; ATP synthase subunit alpha; ATP synthase subunit alpha mitochondrial; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit 1; cardiac muscle; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; 1; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform 1; cardiac muscle; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform 2; non-cardiac muscle-like 2; ATP sythase F1 ATPase; alpha subunit; ATP5A; Atp5a1; ATP5AL2; ATPA_HUMAN; ATPM; Epididymis secretory sperm binding protein Li 123m; hATP1; HEL-S-123m; MC5DN4; mitochondrial; Mitochondrial ATP synthetase; Mitochondrial ATP synthetase oligomycin resistant; Modifier of Min 2; Modifier of Min 2 mouse homolog; Modifier of Min 2; mouse; homolog of; MOM2; OMR; ORM; OTTHUMP00000163475

    Human E. coli
    ATP5F1A is an important component of mitochondrial ATP synthase (complex V) that coordinates ATP production from ADP by utilizing the transmembrane proton gradient. As part of the F-type ATPase, the α and β subunits of ATP5F1A form the catalytic core to achieve ATP hydrolysis. ATP5F1A Protein, Human (His-SUMO) is the recombinant human-derived ATP5F1A protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of ATP5F1A Protein, Human (His-SUMO) is 510 a.a., with molecular weight of ~71.2 kDa.
  • HY-P72097
    ATP5D Protein, Human (His-SUMO)

    ATP synthase subunit delta; mitochondrial ; ATP synthase subunit delta; mitochondrial; ATP synthase; H+ transporting; mitochondrial F1 complex; delta subunit; ATP5D; ATPD_HUMAN; F ATPase delta subunit ; F-ATPase delta subunit; Mitochondrial ATP synthase complex delta subunit precusor ; Mitochondrial ATP synthase delta subunit

    Human E. coli
    ATP5D Protein, a vital component of mitochondrial membrane ATP synthase (Complex V), facilitates ATP generation from ADP using the proton gradient established by respiratory chain electron transport complexes. As part of the F(1) domain and central stalk, ATP5D contributes to ATP hydrolysis through a rotary mechanism. The ATP synthase complex, involving ATP5D, is pivotal for cellular energy production via ATP synthesis. ATP5D Protein, Human (His-SUMO) is the recombinant human-derived ATP5D protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of ATP5D Protein, Human (His-SUMO) is 146 a.a., with molecular weight of ~31 kDa.
  • HY-P75586
    ATP1B1 Protein, Human (HEK293, His)

    Sodium/potassium-transporting ATPase subunit beta-1; ATP1B1; ATP1B

    Human HEK293
    The ATP1B1 protein is the non-catalytic component of ATP hydrolase and promotes Na(+)/K(+) ion exchange across the plasma membrane. Its regulatory role involves the assembly of α/β heterodimers to control sodium pump levels. ATP1B1 Protein, Human (HEK293, His) is the recombinant human-derived ATP1B1 protein, expressed by HEK293 , with N-His labeled tag. The total length of ATP1B1 Protein, Human (HEK293, His) is 241 a.a., with molecular weight of 40-47 kDa.
  • HY-P75587
    ATP1B2 Protein, Human (HEK293, His)

    Sodium/potassium-transporting ATPase subunit beta-2; AMOG; ATP1B2

    Human HEK293
    The ATP1B2 protein is the non-catalytic component of ATP hydrolase and promotes Na(+)/K(+) ion exchange across the plasma membrane. Its role is critical in mediating cell adhesion of neurons and astrocytes, promoting sticky cell interactions. ATP1B2 Protein, Human (HEK293, His) is the recombinant human-derived ATP1B2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ATP1B2 Protein, Human (HEK293, His) is 223 a.a., with molecular weight of ~27.7 kDa.
  • HY-P701354
    ABCC4 Protein, Human (HEK293, GFP, Strep, His)

    ABCC4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; Multidrug resistance-associated protein 4

    Human HEK293
    ABCC4 Protein, an ATP-binding cassette (ABC) family member, actively transports endogenous compounds (cAMP, cGMP, bile acids) and xenobiotics from cells. Its versatility extends to glutathione conjugates (LTC4, LTB4) and drug metabolites, mediating cotransport of bile acids with reduced glutathione. ABCC4's function includes resistance to anticancer agents like methotrexate, highlighting its role in cellular communication and drug transport. ABCC4 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived ABCC4 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of ABCC4 Protein, Human (HEK293, GFP, Strep, His) is 1325 a.a., .
  • HY-P701357
    ABCA1 Protein, Human (Sf9, His, Strep, FLAG)

    ABCA1; ABC1; CERP

    Human Sf9 insect cells
    The ABCA1 protein catalyzes the translocation of specific phospholipids from the cytoplasm to the extracellular/luminal membrane leaflet in response to ATP hydrolysis. It achieves phospholipid translocation by forcing phospholipids through its channels and loops into elongated hydrophobic tunnels in its extracellular domain. ABCA1 Protein, Human (Sf9, His, Strep, FLAG) is the recombinant human-derived ABCA1 protein, expressed by Sf9 insect cells , with N-Strep, C-Flag, N-8*His labeled tag. The total length of ABCA1 Protein, Human (Sf9, His, Strep, FLAG) is 2260 a.a., .
  • HY-P702383
    MT-ND1 Protein, Lampetra fluviatilis (Cell-Free, His, SUMO)

    NADH-ubiquinone oxidoreductase chain 1; NADH dehydrogenase subunit 1; MTND1, NADH1, ND1

    Others E. coli Cell-free
    MT-ND1 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) and is considered an important component of catalysis within the minimal assembly required for its function. As part of Complex I, MT-ND1 plays a crucial role in promoting electron transfer from NADH to the respiratory chain, helping to increase the overall efficiency of mitochondrial oxidative phosphorylation. MT-ND1 Protein, Lampetra fluviatilis (Cell-Free, His, SUMO) is the recombinant MT-ND1 protein, expressed by E. coli Cell-free , with N-10*His, N-SUMO labeled tag. The total length of MT-ND1 Protein, Lampetra fluviatilis (Cell-Free, His, SUMO) is 321 a.a., with molecular weight of 53.8 kDa.
  • HY-P701355
    bABCC1 Protein, Human (HEK293, GFP, Strep, His)

    ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter

    Human HEK293
    The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of bABCC1 Protein, Human (HEK293, GFP, Strep, His) is 1530 a.a., .
  • HY-P701356
    bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His)

    ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter

    Human HEK293
    bABCC1 Protein plays a pivotal role in cellular physiology, mediating the ATP-dependent export of various substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. Despite relatively low ATP hydrolysis efficiency, bABCC1 is crucial in exporting sphingosine 1-phosphate and leukotriene C4, impacting inflammatory responses. It also acts as a negative regulator of the cGAS-STING pathway by mediating ATP-dependent, GSH-independent export of cyclic GMP-AMP (cGAMP). The diverse substrate range and its role in drug resistance highlight the significance of bABCC1 in cellular homeostasis and therapeutic response, necessitating further investigation into precise molecular mechanisms and therapeutic implications. bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag and E1454Q mutation. The total length of bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is 1530 a.a., .
Cat. No. Product Name Effect Purity