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  4. ATP1B2 Protein, Human (HEK293, His)

ATP1B2 Protein, Human (HEK293, His)

Cat. No.: HY-P75587
Handling Instructions

The ATP1B2 protein is the non-catalytic component of ATP hydrolase and promotes Na(+)/K(+) ion exchange across the plasma membrane. Its role is critical in mediating cell adhesion of neurons and astrocytes, promoting sticky cell interactions. ATP1B2 Protein, Human (HEK293, His) is the recombinant human-derived ATP1B2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ATP1B2 Protein, Human (HEK293, His) is 223 a.a., with molecular weight of ~27.7 kDa.

For research use only. We do not sell to patients.

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Description

The ATP1B2 protein is the non-catalytic component of ATP hydrolase and promotes Na(+)/K(+) ion exchange across the plasma membrane. Its role is critical in mediating cell adhesion of neurons and astrocytes, promoting sticky cell interactions. ATP1B2 Protein, Human (HEK293, His) is the recombinant human-derived ATP1B2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ATP1B2 Protein, Human (HEK293, His) is 223 a.a., with molecular weight of ~27.7 kDa.

Background

The ATP1B2 protein functions as the non-catalytic component of the active enzyme responsible for catalyzing ATP hydrolysis coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. While the precise function of the beta-2 subunit remains elusive, it plays a crucial role in mediating cell adhesion for both neurons and astrocytes, contributing to the cohesive interaction between these cells. Additionally, ATP1B2 promotes neurite outgrowth, suggesting its involvement in the intricate processes that regulate the extension of neuronal projections. These cellular functions highlight ATP1B2's significance not only in ion transport but also in mediating adhesion and facilitating the structural development of neural networks.

Species

Human

Source

HEK293

Tag

N-His

Accession

P14415 (D68-T290)

Gene ID

482  [NCBI]

Molecular Construction
N-term
His
ATP1B2 (D68-T290)
Accession # P14415
C-term
Synonyms
Sodium/potassium-transporting ATPase subunit beta-2; AMOG; ATP1B2
Molecular Weight

Approximately 27.7 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

ATP1B2 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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ATP1B2 Protein, Human (HEK293, His)
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HY-P75587
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