2. Recombinant Proteins
  3. Kinases
  4. TKL

TKL

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Cat. No. Product Name / Synonyms Species Source Image
  • HY-P73255
    IRAK4 Protein, Human (Active, sf9, His)

    Interleukin-1 receptor-associated kinase 4; IPD1; IRAK4; NY-REN-64; REN64

    		Human Sf9 insect cells
    The IRAK4 protein is a serine/threonine protein kinase that is critical for initiating the innate immune response through the Toll-like receptor (TLR) and IL-1R signaling pathways. After TLR is activated, it rapidly forms the Myddosome with IRAK2. IRAK4 Protein, Human (Active, sf9, His) is the recombinant human-derived IRAK4 protein, expressed by Sf9 insect cells , with N-10*His labeled tag.
    (1)
  • HY-P74522
    TGFBR1/ALK-5 Protein, Human (Active, sf9, His-GST)

    TGF-beta receptor type-1; ALK-5; SKR4; TbetaR-I; AAT5

    		Human Sf9 insect cells
    TGFBR1/ALK-5 proteins cooperate with TGFBR2 to form dedicated receptors for TGFB1, TGFB2, and TGFB3, transmitting signals and coordinating different physiological and pathological processes. It induces cell cycle arrest, modulates mesenchymal cell dynamics, contributes to wound healing, and affects immunosuppression and carcinogenesis. TGFBR1/ALK-5 Protein, Human (sf9, His-GST) is the recombinant human-derived TGFBR1/ALK-5 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
  • HY-P71853
    RIPK3 Protein, Mouse (P.pastoris, His)

    Ripk3; Rip3; Receptor-interacting serine/threonine-protein kinase 3; EC 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3; mRIP3

    		Mouse P. pastoris
    RIPK3 Protein, participates in programmed necrosis (necroptosis) and apoptosis, contributing to diverse cellular processes. RIPK3 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived RIPK3 protein, expressed by P. pastoris , with N-6*His labeled tag.
  • HY-P71855
    RIPK3 Protein, Human (P.pastoris, His)

    Receptor interacting protein 3; Receptor interacting serine threonine kinase 3; RIP like protein kinase 3; RIP-3; RIP-like protein kinase 3; RIPK 3

    		Human P. pastoris
    RIPK3 is a kinase that controls necroptosis and apoptosis. In necroptosis, activated by TNF-α and ZBP1, RIPK3 phosphorylates MLKL, leading to membrane damage. RIPK3 Protein, Human (P.pastoris, His) is the recombinant human-derived RIPK3 protein, expressed by P. pastoris , with N-6*His labeled tag.
  • HY-P76174
    BMPRIB/ALK-6 Protein, Human (sf9, His-GST)

    Bone morphogenetic protein receptor type-1B; BMPR-1B; CDw293

    		Human Sf9 insect cells
    BMPR1B/ALK-6 protein is a type I member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR1B/ALK-6 is the receptor for BMP-7/OP-1 and GDF-5, positively regulates chondrocyte differentiation through GDF-5 interaction. BMPR1B/ALK-6 also involves in SCUBE3/BMP-2/BMP-4 signals regulation, controlling growth, morphogenesis, and bone and teeth development. ALK-6/GDF-9/BMP-15 signals is essential in prolificacy of goat. The human BMPR1B/ALK-6 protein contains 502 amino acids and a transmembrane domain (127-148 a.a.). BMPRIB/ALK-6 Protein, Human (sf9, His-GST) is produced by HEK293 cells (R149-L502) with N-terminal His- and GST-tag.
    (1)
  • HY-P700624
    RIPK2 Protein, Human (P. pastoris, His)

    receptor-interacting serine-threonine kinase 2; receptor-interacting serine/threonine-protein kinase 2; CARD3; CARDIAK; RICK; RIP2; RIP-2; CARD-carrying kinase; growth-inhibiting gene 30; tyrosine-protein kinase RIPK2; receptor interacting protein 2; receptor-interacting protein 2; RIP-like-interacting CLARP kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; CCK; GIG30;

    		Human P. pastoris
    RIPK2 is a multifunctional serine/threonine/tyrosine protein kinase that coordinates innate and adaptive immune responses. It is activated by bacterial peptidoglycan to form filaments in the NOD1 and NOD2 pathways, undergoing autophosphorylation and polyubiquitination. RIPK2 Protein, Human (P. pastoris, His) is the recombinant human-derived RIPK2 protein, expressed by P. pastoris , with C-6*His, C-6*His labeled tag.
  • HY-P701768
    RIPK1 Protein, Human (sf9, His, GST)

    RIPK1; Receptor-interacting serine/threonine-protein kinase 1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1

    		Human Sf9 insect cells
    RIPK1 protein is a serine-threonine kinase that centrally regulates TNF-mediated apoptosis, necroptosis, and inflammatory pathways. Functionally, it plays a kinase-dependent role in the regulation of cell death and a kinase-independent scaffolding function in the control of inflammatory signaling and cell survival. RIPK1 Protein, Human (sf9, His, GST) is the recombinant human-derived RIPK1 protein, expressed by sf9 insect cells , with N-8*His, N-GST labeled tag.
  • HY-P701789
    IRAK1 Protein, Human (Active, sf9, GST)

    IRAK1; Interleukin-1 receptor-associated kinase 1; IRAK-1

    		Human Sf9 insect cells
    IRAK1 is a serine/threonine protein kinase that initiates innate immune responses against pathogens through Toll-like receptor (TLR) and IL-1R signaling. After TLR activation, IRAK1 is recruited by MYD88 and undergoes IRAK4 phosphorylation, autophosphorylation, and kinase activation. IRAK1 Protein, Human (sf9, GST) is the recombinant human-derived IRAK1 protein, expressed by sf9 insect cells , with N-GST labeled tag.
  • HY-P702733
    RAF1 Protein, Human (Y340D, Y341D, sf9, His, GST)

    RAF1; Raf-1 proto-oncogene, serine/threonine kinase; NS5; CRAF; Raf-1; c-Raf; CMD1NN; RAF proto-oncogene serine/threonine-protein kinase; C-Raf proto-oncogene, serine/threonine kinase; Oncogene RAF1; proto-oncogene c-RAF; raf proto-oncogene serine/threonine protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-1 murine leukemia viral oncogene-like protein 1; EC 2.7.11.1

    		Human Sf9 insect cells
    RAF1 is a kinase that links Ras GTPases to the MAPK/ERK cascade, influencing cell fate decisions. Activated RAF1 initiates the MAPK cascade and phosphorylates MEK1/2 and ERK1/2. RAF1 Protein, Human (Y340D, Y341D, sf9, His, GST) is the recombinant human-derived RAF1, expressed by Sf9 insect cells, with His, GST labeled tag.
  • HY-P702921
    BRAF Protein, Human (Active, sf9, GST, His)

    BRAF1; RAFB; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1

    		Human Sf9 insect cells
    BRAF Protein, Human (Active, sf9, GST, His) is the recombinant human-derived BRAF, expressed by Sf9 insect cells .
  • HY-P703591
    TAK1-TAB1 Protein, Human (sf9)

    TAK1-TAB1

    		Human Sf9 insect cells
  • HY-P702574
    MLKL Protein, Human (His)

    hMLKL; Mixed lineage kinase domain like

    		Human E. coli
    MLKL protein is a pseudokinase that plays a key role in TNF-induced necroptosis. Despite lacking intrinsic kinase activity, it is activated through RIPK3 phosphorylation, leading to homotrimerization, plasma membrane localization, and execution of necroptosis. MLKL Protein, Human (His) is the recombinant human-derived MLKL protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P704200
    RIPK1 Protein, Mouse (C-His)

    Ripk1; Rinp; Rip; Receptor-interacting serine/threonine-protein kinase 1; EC 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1

    		Mouse E. coli
    RIPK1 Protein, Mouse (C-His) is the recombinant mouse-derived RIPK1 protein, expressed by E. coli, with C-6*His tag.
  • HY-P701711
    BMX Protein, Human (Active, sf9)

    BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38

    		Human Sf9 insect cells
    BMX proteins are nonreceptor tyrosine kinases that centrally regulate various signaling pathways that control actin dynamics, migration, proliferation, and survival. BMX participates in signal transduction of multiple receptors such as integrins, growth factor receptors, and cytokine receptors, induces BCAR1 tyrosine phosphorylation, and plays a key role in TNF-induced angiogenesis. BMX Protein, Human (sf9) is the recombinant human-derived BMX protein, expressed by sf9 insect cells , with tag free.
  • HY-P701712
    BMX Protein, Human (sf9, His)

    BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38

    		Human Sf9 insect cells
    BMX proteins are nonreceptor tyrosine kinases that centrally regulate various signaling pathways that control actin dynamics, migration, proliferation, and survival. BMX participates in signal transduction of multiple receptors such as integrins, growth factor receptors, and cytokine receptors, induces BCAR1 tyrosine phosphorylation, and plays a key role in TNF-induced angiogenesis. BMX Protein, Human (sf9, His) is the recombinant human-derived BMX protein, expressed by sf9 insect cells , with N-8*His labeled tag.
  • HY-P701792
    LIMK1 Protein, Human (D460N, sf9)

    LIMK1; LIM domain kinase 1; LIMK-1

    		Human Sf9 insect cells
    The LIMK1 protein is an important serine/threonine protein kinase that controls actin dynamics downstream of Rho GTPases. Activation of ROCK1, PAK1, and PAK4 phosphorylates LIMK1, allowing it to phosphorylate and inhibit actin depolymerizing factors, including cofilin-1/CFL1 and destrin/DSTN. LIMK1 Protein, Human (D460N, sf9) is the recombinant human-derived LIMK1 protein, expressed by sf9 insect cells , with tag free.
  • HY-P701793
    LIMK1 Protein, Human (D460N, sf9, His)

    LIMK1; LIM domain kinase 1; LIMK-1

    		Human Sf9 insect cells
    The LIMK1 protein is an important serine/threonine protein kinase that controls actin dynamics downstream of Rho GTPases. Activation of ROCK1, PAK1, and PAK4 phosphorylates LIMK1, allowing it to phosphorylate and inhibit actin depolymerizing factors, including cofilin-1/CFL1 and destrin/DSTN. LIMK1 Protein, Human (D460N, sf9, His) is the recombinant human-derived LIMK1 protein, expressed by sf9 insect cells , with N-8*His labeled tag.
  • HY-P702732
    IRAK4 Protein, Human (Active, 307a.a, sf9, His)

    Interleukin-1 receptor-associated kinase 4; IPD1; IRAK4; NY-REN-64; REN64

    		Human Sf9 insect cells
    The IRAK4 protein is a serine/threonine protein kinase that is critical for initiating the innate immune response through the Toll-like receptor (TLR) and IL-1R signaling pathways. After TLR is activated, it rapidly forms the Myddosome with IRAK2. IRAK4 Protein, Human (307a.a, sf9, His) is the recombinant human-derived IRAK4, expressed by Sf9 insect cells, with His labeled tag.
  • HY-P702929
    MLK3 Protein, Human (Active, sf9, His-GST)

    MLK3; PTK1; SPRK; MAP3K11

    		Human Sf9 insect cells
    MLK3 Protein, Human (Active, sf9, GST) is the recombinant human-derived MLK3, expressed by Sf9 insect cells , with N-GST labeled tag. ,
  • HY-P702935
    RIPK1 Protein, Rat (Active, sf9, GST)

    Receptor interacting serine/threonine kinase 1 Imported; Ripk1

    		Rat Sf9 insect cells
    RIPK1 Protein, Rat (Active, sf9, GST) is the recombinant rat-derived RIPK1, expressed by Sf9 insect cells , with N-GST labeled tag. ,
Cat. No. Product Name Effect Purity