2. Recombinant Proteins
  3. CD Antigens
  4. Epithelial cell CD Proteins Endothelial cell CD Proteins
  5. IL-1R1/CD121a

IL-1R1/CD121a

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Cat. No. Product Name / Synonyms Species Source
  • HY-P74822
    IL-1R1 Protein, Rat (HEK293, His)

    Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1

    		Rat HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB, MAPK pathways . IL-1R1 Protein, Rat (HEK293, His) is a recombinant rat extracellular region of IL-1R1 (M1-K352) with a C terminal His tag, which is produced in HEK293 cells.
  • HY-P70286
    IL-1R1 Protein, Mouse (HEK293, His)

    rMuInterleukin-1 receptor type 1/IL-1R1, His ; Interleukin-1 receptor type 1; IL-1R-1; IL-1RT1; IL-1 RI; CD121a

    		Mouse HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB and MAPK pathway. IL-1R1 Protein, Mouse (HEK293, His) is a recombinant mouse extracellular region of IL-1R1 (L20-K338) with a C terminal 6*His tag, which is produced in HEK293 cells.
  • HY-P72569
    IL-1R1 Protein, Human (315a.a, HEK293, His)

    Interleukin-1 receptor type 1; IL-1R-1; IL-1RT-1; Interleukin-1 receptor alpha; IL-1R-alpha; p80; CD121a    

    		Human HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB and MAPK pathway. IL-1R1 Protein, Human (315a.a, HEK293, His) is a recombinant human extracellular region of IL-1R1 (L18-T332) with a C-Terminal 6*His tag, which is produced in HEK293 cells.
  • HY-P74823
    IL-1R1 Protein, Human (HEK293)

    Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1

    		Human HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB and MAPK pathway. I IL-1R1 Protein, Human (HEK293) is a recombinant human extracellular region of IL-1R1 (M1-T332) without any tag, which is produced in HEK293 cells.
  • HY-P76996
    IL-1R1 Protein, Cynomolgus (HEK293, His)

    Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1

    		Cynomolgus HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB and MAPK pathway. IL-1R1 Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus extracellular region of IL-1R1 (M1-T332) with a C-Terminal His tag, which is produced in HEK293 cells.
  • HY-P71876A
    IL-1RN Protein, Horse (His)

    IL1RN; IL1RAInterleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; IRAP; IL1 inhibitor

    		Equine E. coli
    IL-1RN protein, an anti-inflammatory antagonist, safeguards against immune dysregulation and systemic inflammation triggered by IL1. It acts on proinflammatory cytokines, including IL1B and IL1A, countering the effects of IL1. Particularly responsive to innate stimulatory agents like pathogens, IL-1RN helps mitigate the inflammatory response, ensuring immune homeostasis. IL-1RN Protein, Horse (His) is the recombinant equine-derived IL-1RN protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-1RN Protein, Horse (His) is 152 a.a., with molecular weight of ~18 kDa.
  • HY-P73894A
    IL-1RA/IL-1RN Protein, Rat (C-His)

    Interleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; Il1rn

    		Rat E. coli
    The IL-1RA/IL-1RN mutant protein, an enhanced anti-inflammatory antagonist in the interleukin-1 family, specifically targets proinflammatory cytokines IL1B and IL1A. Engineered for increased inhibitory capabilities, this mutant variant critically safeguards the host from immune dysregulation and prevents uncontrolled systemic inflammation triggered by IL1 in response to innate stimulatory agents. Offering optimized defense against IL1-mediated inflammation, the mutant protein significantly contributes to maintaining immune balance and preventing excessive inflammation. IL-1RA/IL-1RN Protein, Rat (C-His) is the recombinant rat-derived IL-1RA/IL-1RN protein, expressed by E. coli, with C-6*His labeled tag. The total length of IL-1RA/IL-1RN Protein, Rat (C-His) is 152 a.a., with molecular weight of ~19.94 kDa.
  • HY-P73185
    IL-1R1 Protein, Human (HEK293, Fc)

    Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1

    		Human HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB and MAPK pathway. IL-1R1 Protein, Human (HEK293, Fc) is a recombinant human extracellular region of IL-1R1 (M1-T332) with a C-Terminal hFc tag, which is produced in HEK293 cells.
  • HY-P76995
    IL-1R1 Protein, Cynomolgus (HEK293, Fc)

    Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1

    		Cynomolgus HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB and MAPK pathway. IL-1R1 Protein, Cynomolgus (HEK293, Fc) is a recombinant cynomolgus extracellular region of IL-1R1 (M1-T332) with a C-Terminal hFc tag, which is produced in HEK293 cells.
  • HY-P74821
    IL-1R1 Protein, Rat (HEK293, His-mFc)

    Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1

    		Rat HEK293
    IL-1R1 (CD121a) belongs to IL-1 receptor, and binds to IL-1α, IL-1β, IL-1Ra and IL-38 with comparable affinities (Kd: 0.1-1 nM). IL-1R1 regulates the transcription of multiple proinflammatory cytokines and mediates immune and inflammatory responses, including the activation of NF-κB, MAPK pathways. IL-1R1 Protein, Rat (HEK293, His-mFc) is a recombinant rat extracellular region of IL-1R1 (M1-K352) with C terminal His and hFc tags, which is produced in HEK293 cells.
Cat. No. Product Name Effect Purity