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  6. Cysteine Protease Focused Library
Cysteine Protease Focused Library

Cat. No.: HY-L925

Cysteine proteases (CPs), a key enzyme family regulating physiological metabolism and mediating pathological processes (such as abnormal bone resorption, tumour invasion, and pathogen infection), represent a core therapeutic target for developing specific inhibitors in disease intervention. Currently reported CP inhibitors primarily achieve their inhibitory function by precisely binding to CP active pockets (e.g., S1-S4 non-primed regions or S1'-S2' primed regions) and forming covalent/non-covalent interactions with the active site cysteine residues, providing clear structural references for the development of novel inhibitors.

This compound library, designed based on the core strategy of "similarity-based known active structures", contains over 200 cysteine protease inhibitors. Leveraging AI-driven molecular screening technology, it retains the critical pharmacological and shape features of reported CP inhibitors, serving as a specialized tool for efficiently discovering novel cysteine protease inhibitors.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Description & Advantages

•    A unique collection of 9,192 compounds can be used for efficient discovery of novel cysteine protease inhibitors.

•    All compounds are screened via AI models to get a collection retaining the critical pharmacological and shape features of reported CP inhibitors.

•   All compounds are available off the shelf.

•   All compounds are validated by LC-MS or NMR to ensure high purity and quality.

Product Details

Formulation:

The 9,192 compounds obtained via AI-driven screening serve as a valuable tool for discovering novel cysteine protease inhibitors.
Solution: 9,191 compounds supplied in 10 mM solution.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.

Storage:

-80°C

Shipping:

Blue ice or dry ice

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    Product Name:
    Cysteine Protease Focused Library
    Cat. No.:
    HY-L925
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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