Traditional Chinese Medicine Active Compound Library

105 Cited Publications
Customer Review

Based on 105 publication(s) in Google Scholar

Chinese herbal therapy is an important part of Traditional Chinese Medicine (TCM). It has been used for centuries in China, where herbs are considered fundamental therapy for many acute and chronic conditions. Many studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. Active components from Traditional Chinese Medicine possess many medicinal properties such as antioxidant, anti-cancer, and anti-bacterial effects, which makes it an important source of new drugs. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, artemisinin, used in multidrug resistant malaria, was first isolated from the Chinese herb Artemisia annua L. Today, scientists continue to identify compounds in Chinese herbal remedies that may be useful in the development of new therapeutic agents applicable in Western medicine.

MCE designs a unique collection of 3,276 active compounds of Chinese Herbal Medicines. MCE Traditional Chinese Medicine Active Compound Library is a useful tool for discovery new drugs from TCM.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Service

Description & Advantages

•   A unique collection of 3,276 active compounds of Traditional Chinese Medicine for high throughput screening (HTS) and high content screening (HCS).

•   The compounds in the library contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes.

•   A useful tool for drug discovery as an important source of lead compounds.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 3,276 active compounds of Traditional Chinese Medicine supplied as pre-dissolved Solutions or Solid

Solution: 3,174 compounds supplied in 10 mM solution, 85 compounds supplied in 2 mM solution, 17 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage
-80°C
Shipping
Blue ice or dry ice

Documentation

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  • Excel
  • SDF
  • Manual

Composition

Apoptosis (712)

Bacterial (386)

NF-κB (341)

Autophagy (270)

Akt (175)

Fungal (166)

p38 MAPK (158)

COX (134)

Parasite (133)

Caspase (123)

ERK (114)

PI3K (113)

NO Synthase (100)

TNF Receptor (100)

Keap1-Nrf2 (96)

STAT (84)

JNK (82)

AMPK (61)

MMP (60)

mTOR (60)

PPAR (55)

Antibiotic (45)

Tyrosinase (45)

Amyloid-β (39)

HIV (38)

JAK (35)

PARP (34)

SARS-CoV (32)

SOD (32)

Wnt (31)

PKC (30)

HSV (26)

VEGFR (26)

CDK (25)

MDM-2/p53 (24)

Sirtuin (23)

PERK (22)

β-catenin (22)

GSK-3 (20)

EGFR (19)

FXR (17)

HBV (17)

Mitophagy (17)

HSP (16)

mAChR (16)

Pyroptosis (16)

iGluR (15)

nAChR (15)

PKA (15)

GLUT (14)

MEK (14)

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200 mg
USD 120
In-stock
Estimated to ship on August 31 More
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
500 mg
Get Quote
Consult sales personnel for more information
Bulk Inquiry
Estimated to ship on August 31 More