1. Screening Libraries
  2. Anti-COVID-19 Compound Library

Anti-COVID-19 Compound Library

Cat. No.: HY-L052
Library Contents: XLSX PDF SDF

COVID-19 poses a serious threat to people's health, and it is urgent to develop drugs to treat COVID-19 quickly. The screening of anti-COVID-19 drugs by using the clinical and approved compounds can greatly shorten the research and development cycle. In addition, the virtual screening technology can effectively narrow the scope of screening and improve the screening efficiency in the pre-screening of new drugs.

Taking advantage of our virtual screening, we conduct virtual screening of approved compound library and clinical compound library based on the 3CL protease (PDB ID: 6LU7), Spike Glycoprotein (PDB ID: 6VSB), NSP15 (PDB ID: 6VWW), RDRP, PLPro and ACE2 (Angiotensin Converting Enzyme 2) structure. We design a unique collection of 1557 compounds which may have anti-COVID-19 activity. Anti-COVID-19 Compound Library will be a powerful tool for screening new anti-COVID-19 activity drugs.

MCE Anti-COVID-19 Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 1534 compounds supplied in 10 mM solution, 18 compounds supplied in 2 mM solution and 5 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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Description
& Advantages

•   A unique collection of 1557 compounds that may have anti-COVID-19 activity for high throughput screening (HTS) and high content screening (HCS).

•   All compounds are derived from virtual screening of approved compound library and clinical compound library based on the 3CL protease, Spike Glycoprotein and ACE2 structure.

•   A useful tool for the development of anti-COVID-19 drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials.

•   Structurally diverse, medicinally active, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 1557 compounds that may have anti-COVID-19 activity supplied as pre-dissolved Solutions or Solid
Solution: 1534 compounds supplied in 10 mM solution, 18 compounds supplied in 2 mM solution, 5 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Anti-COVID-19 Compound Library

Source: MedChem Express

Documentation

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    Cat. No.:
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack