2. Recombinant Proteins
  3. CD Antigens
  4. T Cell CD Proteins

T Cell CD Proteins

T Cell CD Proteins

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The cluster of differentiation (CD) antigens a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. The lineage-specific marker for T cells is cytoplasmic CD3, which appears in the earliest T cells as precursors in the thymus. Early T-cell precursors also express CD2 and CD7. During thymic maturation, the T-cell precursor undergoes rearrangements of the T-cell receptor. This process is accompanied by the appearance of other T-cell lineage-associated markers (CD5, CD4, CD8). The majority of the mature T cells are either CD4+ or CD8+. Thymocytes, however, and aberrant neoplastic T cells may coexpress CD4 and CD8 as well as immature T-cell markers TdT and CD1a.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P73499
    CD40 Protein, Human (193a.a, HEK293, His)

    Tumor Necrosis Factor Receptor Superfamily member 5; Bp50; CD40L Receptor; CDw40; TNFRSF5

    		Human HEK293
  • HY-P7395
    PD-1 Protein, Human (CHO, Fc)

    rHuPD-1, Fc Chimera; PD1; CD279; PDCD1

    		Human CHO
    PD-1 Protein, Human (CHO, Fc) suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2.
  • HY-P7396
    PD-1 Protein, Human (143a.a, HEK293, His)

    rHuPD-1, His; PD1; CD279; PDCD1

    		Human HEK293
    PD-1 Protein, Human (143a.a, HEK293, His) suppress activating signals from the T cell receptor when bound by either of its ligands, programmed death-ligand 1 (PD-L1) or PD-L2.
  • HY-P70537
    CD4 Protein, Human (365a.a, HEK293, His)

    T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; sCD4

    		Human HEK293
  • HY-P70731
    CD38 Protein, Human (HEK293, His)

    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; CD38 antigen; CD38 molecule; CD38

    		Human HEK293
  • HY-P70808
    CD40L/CD154/TRAP Protein, Mouse (HEK293, His)

    CD40 Ligand; CD40LG; HIGM1; T-B cell-activating molecule; T-BAM; TNFSF5; tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5

    		Mouse HEK293
    CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in mouse, cleaved into 2 chains of membrane form (1-260 a.a.) and soluble form (112-260 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Mouse (HEK293, His) has a total length of 149 amino acids (M112-L260), is expressed in HEK392 cells with N-terminal 6*His-tag.
  • HY-P70629
    IL-2R alpha Protein, Human (HEK293, Fc)

    IL-2R alpha; IL-2RA; IL-2 R alpha; Interleukin-2 receptor subunit alpha; CD25; p55; TAC antigen; IL2-RA; IL-2R subunit alpha; IL-2-RA; IL-2 receptor subunit alpha

    		Human HEK293
    IL-2R alpha Protein, Human (HEK293, Fc), a recombinant human IL-2RA produced in HEK293 cells, has an Fc fragment at the C-terminus. IL-2RA is a subunit of interleukin-2 receptor, plays a critical role in regulating the IL-2-mediated responses by modulating the affinity of the IL-2R for the ligand.
  • HY-P7374
    IL-2R alpha/CD25 Protein, Human (HEK293, Fc)

    rHuIL-2R α/CD25, Fc Chimera; TAC antigen; IL-2-RA; IL-2 R alpha; IL-2Rα; IL2RA

    		Human HEK293
    IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Human (HEK293, Fc) is a recombinant human IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 192 amino acids (E22-C213).
  • HY-P70824
    CD3 epsilon Protein, Human (27a.a, HEK293, Fc)

    T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e; CD3E; T3E

    		Human HEK293
  • HY-P7168
    Fas/CD95 Protein, Human (HEK293)

    rHuFASR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; FAS1; Apo-1

    		Human HEK293
    Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293) has a full length of 157 amino acids (Q26-S172), produced in HEK293 cells with tag free.
  • HY-P73682
    RANK L/TNFSF11 Protein, Human (HEK293, Fc)

    Tumor necrosis factor ligand superfamily member 11; ODF; RANKL; CD254; TNFSF11

    		Human HEK293
    RANKL (TNFSF11), a type II transmembrane protein, is a receptor ligand for NF-κB (RANK). RANKL is an activator of NF-κB. When binding to NF-κB, it induces the differentiation of monocyte/macrophage-lineage cells into osteoclasts and leads to osteoclast precursor maturation. RANKL is critical for osteoclasts maturation, bone modeling, and bone remodeling, as well as the development of lymph nodes (LNs). RANKL/TNFSF11 Protein, Human (HEK293, Fc) is a recombinant human RANKL (G63-D244) with N-terminal mFc tag, which is produced in HEK293 cell.
  • HY-P70010
    CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His)

    rHu5'-nucleotidase/CD73, His; 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE

    		Human HEK293
  • HY-P70506
    CD3 epsilon Protein, Human (HEK293, His)

    T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e; CD3E; T3E

    		Human HEK293
  • HY-P70525
    PD-1 Protein, Human (HEK293, mFc)

    Programmed cell death protein 1; hPD-1; PDCD1; CD279

    		Human HEK293
  • HY-P70609G
    GMP CD40L/CD154/TRAP Protein, Human (HEK293)

    CD40 ligand; CD40-L; TRAP; CD154; TNFSF5

    		Human HEK293
    CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Human (HEK293) has a total length of 149 amino acids (M113-L261), is expressed in HEK293 cells with tag free.
  • HY-P70651
    B7-1/CD80 Protein, Human (208a.a, HEK293, His)

    CD80; Activation B7-1 antigen; B7; BB1; CD28LG1; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80

    		Human HEK293
  • HY-P70684
    CTLA-4 Protein, Human (126a.a, HEK293, His)

    Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4

    		Human HEK293
  • HY-P70691
    CTLA-4 Protein, Human (HEK293, GST)

    Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4

    		Human HEK293
    CTLA-4 Protein, Human (HEK293, GST) is negative regulator of T-cell immune function.
  • HY-P70706
    CTLA-4 Protein, Mouse (125a.a, HEK293, Fc)

    Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; Ctla4

    		Mouse HEK293
  • HY-P70762
    CD28 Protein, Human/Cynomolgus (HEK 293, Fc)

    CD28; CD28 antigen; CD28 molecule; T-cell-specific surface glycoprotein CD28; Tp44; TP44

    		Human; Cynomolgus HEK293
Cat. No. Product Name Effect Purity