2. Recombinant Proteins
  3. Ubiquitin Related Proteins
  4. Deubiquitinase
  5. Ubiquitin-Specific Protease

Ubiquitin-Specific Protease

Recombinant Protein Expression Service

Ubiquitin-Specific Protease

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Cat. No. Product Name / Synonyms Species Source
  • HY-P74479
    USP5 Protein, Human (sf9, His)

    Ubiquitin carboxyl-terminal hydrolase 5; Isopeptidase T; USP5; ISOT

    		Human Sf9 insect cells
    USP5 protein selectively cleaves branched multiubiquitin polymers, favoring 'Lys-48'-linked polyubiquitin disassembly. It exhibits lower affinity for linear and 'Lys-63'-linked polyubiquitin. USP5 knockdown leads to p53/TP53 accumulation, enhancing p53/TP53 transcriptional activity, as unanchored polyubiquitin competes with ubiquitinated p53/TP53 for proteasomal recognition, unlike MDM2. USP5 Protein, Human (sf9, His) is the recombinant human-derived USP5 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of USP5 Protein, Human (sf9, His) is 835 a.a., with molecular weight of ~100 kDa.
  • HY-P71418
    USP14 Protein, Human (His)

    Ubiquitin Carboxyl-Terminal Hydrolase 14; Deubiquitinating Enzyme 14; Ubiquitin Thioesterase 14; Ubiquitin-Specific-Processing Protease 14; USP14; TGT

    		Human E. coli
    USP14 is a proteasome-associated deubiquitinase that regulates ubiquitin dynamics by releasing ubiquitin from proteins marked for degradation. As a reversible proteasome subunit, USP14 ensures ubiquitin replenishment. USP14 Protein, Human (His) is the recombinant human-derived USP14 protein, expressed by E. coli , with N-6*His labeled tag. The total length of USP14 Protein, Human (His) is 404 a.a., with molecular weight of 47-52 kDa.
  • HY-P700272
    USP14 Protein, Human (N-His)

    Ubiquitin Carboxyl-Terminal Hydrolase 14; Deubiquitinating Enzyme 14; Ubiquitin Thioesterase 14; Ubiquitin-Specific-Processing Protease 14; USP14; TGT

    		Human E. coli
    USP14, a proteasome-associated deubiquitinase, regulates ubiquitin dynamics by releasing it from proteins marked for degradation. As a reversible proteasome subunit, USP14 ensures ubiquitin replenishment. Beyond proteasomal protein turnover, it degrades CXCR4 for cell chemotaxis and inhibits ERAD under non-stressed conditions. USP14 also aids synaptic development at NMJs and stabilizes CGAS for antiviral defense, revealing its multifaceted role in cellular processes. USP14 Protein, Human (N-His) is the recombinant human-derived USP14 protein, expressed by E. coli, with N-6*His labeled tag. The total length of USP14 Protein, Human (N-His) is 494 a.a., with molecular weight of ~60 kDa.
  • HY-P77277
    USP46 Protein, Human/Mouse (sf9)

    Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme 46; Usp46

    		Human; Mouse Sf9 insect cells
    USP46 Protein, a ubiquitin-specific protease, is involved in the regulation of cellular processes and protein degradation. It has been found to play a critical role in synaptic plasticity and memory formation. USP46 Protein's potential as a therapeutic target in cognitive disorders and its impact on neurological function make it a subject of interest in neuroscience research. USP46 Protein, Human/Mouse (sf9) is the recombinant human, mouse-derived USP46 protein, expressed by Sf9 insect cells , with tag free. The total length of USP46 Protein, Human/Mouse (sf9) is 366 a.a., with molecular weight of ~43 kDa.
  • HY-P74478
    USP7 Protein, Human (sf9)

    Ubiquitin carboxyl-terminal hydrolase 7; USP7; HAUSP

    		Human Sf9 insect cells
    The USP7 protein is a hydrolase that deubiquitinates multiple targets, including FOXO4, DEPTOR, KAT5, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN, KMT2E/MLL5, and DAXX. It cooperates with DAXX to enhance the E3 ligase activity of MDM2 and promote ubiquitination and degradation of p53/TP53. USP7 Protein, Human (sf9) is the recombinant human-derived USP7 protein, expressed by Sf9 insect cells , with tag free. The total length of USP7 Protein, Human (sf9) is 353 a.a., with molecular weight of ~41 kDa.
  • HY-P702603
    USP7 Protein, Human (His)

    Ubiquitin carboxyl-terminal hydrolase 7; USP7; HAUSP

    		Human E. coli
  • HY-P77278
    USP46 Protein, Human/Mouse (sf9, SUMO)

    Ubiquitin carboxyl-terminal hydrolase 46; Deubiquitinating enzyme 46; Usp46

    		Mouse Sf9 insect cells
    USP46 Protein, a ubiquitin-specific protease, is involved in the regulation of cellular processes and protein degradation. It has been found to play a critical role in synaptic plasticity and memory formation. USP46 Protein's potential as a therapeutic target in cognitive disorders and its impact on neurological function make it a subject of interest in neuroscience research. USP46 Protein, Human/Mouse (sf9, SUMO) is the recombinant mouse-derived USP46 protein, expressed by Sf9 insect cells , with SUMO labeled tag. The total length of USP46 Protein, Human/Mouse (sf9, SUMO) is 366 a.a., with molecular weight of ~64 kDa.
  • HY-P702604
    USP7 Protein, Human

    Ubiquitin carboxyl-terminal hydrolase 7; USP7; HAUSP

    		Human E. coli
Cat. No. Product Name Effect Purity