1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Neurotrophic Factors
  4. CDNF/MANF family

Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) form a new neurotrophic factors family (NTFs) of evolutionarily conserved and may not act as classical, target-derived neurotrophic factors (NTFs) that are solely secreted proteins. CDNF is a vertebrate specific paralogue of MANF. CDNF/MANF are mostly intracellular and localize to the endoplasmic reticulum (ER) under normal conditions and protect cells from ER stress, and regulate the unfolded protein response via interacting with chaperons, and CDNF dissolves intracellular α-synuclein aggregates. In animal models of Parkinson's disease (PD), CDNF protects and repairs dopamine (DA) neurons, regulates ER stress, and improves motor function more efficiently than other NTFs.

Cat. No. Product Name / Synonyms Species Source
Cat. No. Product Name Effect Purity