CDNF/MANF family

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Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) form a new neurotrophic factors family (NTFs) of evolutionarily conserved and may not act as classical, target-derived neurotrophic factors (NTFs) that are solely secreted proteins. CDNF is a vertebrate specific paralogue of MANF. CDNF/MANF are mostly intracellular and localize to the endoplasmic reticulum (ER) under normal conditions and protect cells from ER stress, and regulate the unfolded protein response via interacting with chaperons, and CDNF dissolves intracellular α-synuclein aggregates. In animal models of Parkinson's disease (PD), CDNF protects and repairs dopamine (DA) neurons, regulates ER stress, and improves motor function more efficiently than other NTFs.

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CDNF/MANF family Recombinant Proteins (9)

Species:	Human (6) Mouse (3)
Tag:	His (7) Fc (2)
Source:	E. coli (3) HEK293 (6)

Cat. No.	Product Name / Synonyms	Species	Source

HY-P71940A

ARMET/MANF Protein, Human (His) Arginine rich mutated in early stage tumors; Arginine rich protein; Arginine-rich protein; ARMET; ARMET protein; ARP; Manf; MANF_HUMAN; Mesencephalic astrocyte derived neurotrophic factor; Mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET	Human	E. coli

HY-P70069

CDNF Protein, Human (163a.a, HEK293, His) rHuCerebral dopamine neurotrophic factor/CDNF, His ; Cerebral dopamine neurotrophic factor; ARMET-like protein 1; Conserved dopamine neurotrophic factor; ARMETL1	Human	HEK293

HY-P7605

ARMET/MANF Protein, Human (158a.a, HEK293, His) rHuARMET/MANF, His; Mesencephalic astrocyte-derived neurotrophic factor; ARMET	Human	HEK293
ARMET/MANF Protein, Human (158a.a, HEK293, His) expresses in HEK293 cells with a His tag. Armet/MANF, localized in the ER and Golgi, is a secreted protein and acts as a gene up-regulated by various forms of ER stress.

HY-P700038AF

Animal-Free CDNF Protein, Human (His)
Cerebral dopamine neurotrophic factor; ARMET-like protein 1; Conserved dopamine neurotrophic factor; ARMETL1
Human E. coli
HY-P77296

ARMET/MANF Protein, Mouse (HEK293, His)
Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; ARP
Mouse HEK293
HY-P700166AF

Animal-Free CDNF Protein, Mouse (His)
Cerebral dopamine neurotrophic factor; CDNF; ARMETL1
Mouse E. coli
HY-P76248

CDNF Protein, Human (HEK293, Fc)
Cerebral dopamine neurotrophic factor; ARMET-like protein 1; ARMETL1
Human HEK293
HY-P75670

CDNF Protein, Mouse (HEK293, His)
Cerebral dopamine neurotrophic factor; CDNF; ARMETL1
Mouse HEK293
HY-P76731

ARMET/MANF Protein, Human (HEK293, Fc)
Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; ARP
Human HEK293

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CDNF/MANF family

CDNF/MANF family

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CDNF/MANF family Recombinant Proteins (9)