1. Recombinant Proteins
  2. CD Antigens
  3. Platelet CD Proteins

The cluster of differentiation (CD) antigens is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. Platelets are the smallest blood cells that are cytoplasmic fragments derived from their bone marrow precursor, the megakaryocyte. Quiescent platelets express a large number of surface proteins, including CD9, CD29, CD31, CD36, CD41, CD42a, CD42b, CD61 and GPVI2,3. Surface levels of some of these molecules (e.g., CD41 and CD61) are increased following platelet activation, while other proteins which are virtually absent from the surface of resting platelets, such as CD62P, CD63, CD107a and CD154, are translocated from intracellular stores to the plasma membrane following activation.

Cat. No. Product Name / Synonyms Species Source
  • HY-P72359
    CD47 Protein, Human (Biotinylated, HEK293, Avi-His)

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; IAP; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is 121 a.a., with molecular weight of 30-55 kDa.
  • HY-P72022
    SLAMF2/CD48 Protein, Human (HEK293, hFc)

    B-lymphocyte activation marker BLAST-1 BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48; BCM1; BLAST1;

    Human HEK293
    SLAMF2/CD48 protein is a GPI-anchored glycoprotein that regulates immune cell function by interacting with CD2 and CD244. SLAMF2/CD48 Protein, Human (HEK293, hFc) is the recombinant human-derived SLAMF2/CD48 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SLAMF2/CD48 Protein, Human (HEK293, hFc) is 194 a.a., with molecular weight of ~66 kDa.
  • HY-P70820
    CD47 Protein, Mouse (HEK293, His)

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6

    Mouse HEK293
    CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-6*His labeled tag. The total length of CD47 Protein, Mouse (HEK293, His) is 140 a.a., with molecular weight of 30-60 kDa.
  • HY-P72892
    CD31/PECAM-1 Protein, Human

    Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; PECA1; CD31

    Human HEK293
    CD31/PECAM-1 Protein, a pivotal cell adhesion molecule, is essential for leukocyte transendothelial migration (TEM) in most inflammatory conditions. PECAM1 modulates bradykinin receptor BDKRB2 activation and regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells. Signaling through PECAM-1 leads to the activation of neutrophils, monocytes and leukocytes. CD31/PECAM-1 Protein, Human is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with tag free.
  • HY-P72895
    CD36 Protein, Mouse (HEK293, His)

    Glycoprotein IIIb; GPIIIB; PAS IV; PAS-4; Platelet glycoprotein 4; GPIV; CD36

    Mouse HEK293
    CD36 is the subject in the following active sentence patterns mentioned in the paragraph: CD36 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD36 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD36 Protein, Mouse (HEK293, His) is 410 a.a., with molecular weight of 75-90 kDa.
  • HY-P72917
    CD47 Protein, Human (HEK293)

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (HEK293) is the recombinant human-derived CD47 protein, expressed by HEK293 , with tag free. The total length of CD47 Protein, Human (HEK293) is 121 a.a., with molecular weight of 35-48 kDa.
  • HY-P72918
    CD47 Protein, Mouse (Q61735-1, HEK293, His)

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Mouse HEK293
    The CD47 protein is an adhesive multifunctional protein that coordinates cell-cell interactions, serves as a THBS1 receptor, and regulates integrin signaling through heterotrimeric G proteins. It plays a key role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cell self-renewal, immune regulation, and memory formation. CD47 Protein, Mouse (Q61735-1, HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD47 Protein, Mouse (Q61735-1, HEK293, His) is 122 a.a., with molecular weight of 34-44 kDa.
  • HY-P73307
    Nectin-2/CD112 Protein, Human (HEK293)

    Nectin-2; CD112; NECTIN2; PVRL2; HVEB; PRR2

    Human HEK293
    Nectin-2/CD112 protein has dual roles in T-cell signaling: as a costimulator with CD226, promoting proliferation and cytokine production, and as a coinhibitor with PVRIG, inhibiting proliferation. It also acts as a cell adhesion protein and a receptor for certain viruses. Nectin-2/CD112 Protein, Human (HEK293) is the recombinant human-derived Nectin-2/CD112 protein, expressed by HEK293 , with tag free. The total length of Nectin-2/CD112 Protein, Human (HEK293) is 329 a.a., with molecular weight of 45-55 kDa.
  • HY-P7336
    CD47 Protein, Human (HEK293, His)

    rHuCD47, His; CD47; MER6; IAP; OA3

    Human HEK293
    CD47 Protein, Human (HEK293, His) is a polypeptide chain with His tag produced in HEK293 cells. CD47 is a prominent target in cancer immunotherapy.
  • HY-P74370
    Cadherin-1/CD324 Protein, Human (HEK293, Fc)

    Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324

    Human HEK293
    The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-1/CD324 Protein, Human (HEK293, Fc) is 685 a.a., with molecular weight of 116-126 kDa.
  • HY-P75644
    Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, Fc)

    Low Affinity Immunoglobulin Gamma Fc Region Receptor II-a; CD32; FCGR2A; FCG2; IGFR2

    Human HEK293
    Fc gamma RIIA/CD32a Protein plays a pivotal role, specifically binding to the Fc region of immunoglobulins gamma as a low-affinity receptor. Interacting with IgG, it initiates cellular responses against pathogens, crucial for immune modulation. Notably, the protein promotes opsonized antigen phagocytosis, contributing to immune defense. Engaging with IGHG1, INPP5D/SHIP1, INPPL1/SHIP2, APCS, FGR, and HCK, it participates in intricate signaling pathways, highlighting its multifaceted role in orchestrating diverse immune responses. Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, Fc) is the recombinant human-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-hFc labeled tag and H167R mutation. The total length of Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, Fc) is 185 a.a., with molecular weight of ~55 kDa.
  • HY-P77123
    PDGF R beta Protein, Human (HEK293, C-His-Avi)

    Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB

    Human HEK293
    PDGF Rβ protein is integral in embryonic development and regulates cell proliferation, survival, differentiation, chemotaxis, migration, and vascular development. It crucially recruits pericytes and smooth muscle cells to the endothelium, promoting vascular smooth muscle cell migration and neointimal formation at the site of injury. PDGF R beta Protein, Human (HEK293, C-His-Avi) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-His, C-Avi labeled tag.
  • HY-P77719
    Integrin alpha V beta 3 Protein, Human (HEK293, His-Avi)

    Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3

    Human HEK293
    Integrin alpha V beta 5 Proteinas, specifically the alpha-V (ITGAV) subunit, is a versatile receptor for ligands like vitronectin, fibronectin, and others, recognizing the R-G-D sequence. ITGAV:ITGB3 binds fractalkine, acting as a coreceptor in CX3CR1-dependent signaling. It forms crucial interactions with NRG1, FGF1, FGF2, IGF1, IGF2, IL1B, PLA2G2A, FBN1, CD40LG, contributing to diverse pathways. Notably, ITGAV:ITGB3 or ITGAV:ITGB6 is a receptor for TGF-beta-1, mediating its release from LAP and playing a crucial role in TGF-beta-1 activation. Additionally, ITGAV:ITGB5 functions as an Adenovirus type C receptor during microbial infection. Integrin alpha V beta 5's integrative nature underscores its pivotal role in diverse cellular responses and signaling cascades. Integrin alpha V beta 3 Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein, expressed by HEK293, with C-His, C-Avi labeled tag. Integrin alpha V beta 3 Protein, Human (HEK293, His-Avi), has molecular weight of 85-140 kDa.
  • HY-P7779
    LAMP1/CD107a Protein, Human (HEK293, Fc)

    rHuCD107a, C-Fc; Lysosome-Associated Membrane Glycoprotein 1; LAMP-1; Lysosome-Associated Membrane Protein 1; CD107 Antigen-Like Family Member A; CD107a; LAMP1

    Human HEK293
    LAMP1/CD107a Protein, Human (HEK293, Fc) is a recombinant human CD107a expressed in HEK 293 cells with a C-Fc tag at the C-terminus. LAMP1/CD107a Protein can be used as a functional marker for the identification of natural killer cell activity.
  • HY-P7780
    Nectin-2/CD112 Protein, Human (HEK293, His)

    rHuCD112, His; Poliovirus Receptor-Related Protein 2; Herpes Virus Entry Mediator B; Herpesvirus Entry Mediator B; CD112; PVRL2; HVEB; PRR2

    Human HEK293
    CD112 Protein, Human (HEK293, His) is a recombinant human CD112 expressed in HEK 293 cells with a His tag at the N-terminus. Recombinant Human CD112 can be used as cell surface ligands for the human DNAM-1 (CD226) activating molecule.
  • HY-P78095
    CD47 Protein, Human (Biotinylated, HEK293, His-Avi)

    CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, His-Avi) is 121 a.a., with molecular weight of 45-55 kDa.
  • HY-P78100
    Fc gamma RIIA/CD32a Protein, Human (Biotinylated, 183a.a, HEK293, His-Avi)

    CD32MGC23887; CDw32fc-gamma-RIIa; Fc gamma RIIA; FCG2; Fc-gamma-RIIa; FcGR; FCGR2; FCGR2A; FCGR2A1; FcgRIIA; FCRIIA; fcRII-a; IGFR2MGC30032; IgG Fc receptor II-a; FCG2; CD32A

    Human HEK293
    Fc gamma RIIA/CD32a Protein plays a pivotal role, specifically binding to the Fc region of immunoglobulins gamma as a low-affinity receptor. Interacting with IgG, it initiates cellular responses against pathogens, crucial for immune modulation. Notably, the protein promotes opsonized antigen phagocytosis, contributing to immune defense. Engaging with IGHG1, INPP5D/SHIP1, INPPL1/SHIP2, APCS, FGR, and HCK, it participates in intricate signaling pathways, highlighting its multifaceted role in orchestrating diverse immune responses. Fc gamma RIIA/CD32a Protein, Human (Biotinylated, 183a.a, HEK293, His-Avi) is the recombinant human-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and H167 mutation. The total length of Fc gamma RIIA/CD32a Protein, Human (Biotinylated, 183a.a, HEK293, His-Avi) is 183 a.a., with molecular weight of 30-40 kDa.
  • HY-P78114
    DNAM-1 Protein, Human (Biotinylated, HEK293, His-Avi)

    CD226 molecule; CD226; DNAM1; PTA1; TLiSA1

    Human HEK293
    DNAM-1 protein is a key player in cell-cell adhesion and lymphocyte signaling, mediating cytotoxicity and lymphokine secretion of CTL and NK cells. As a receptor for NECTIN2, DNAM-1 stimulates T cell proliferation and cytokine production (IL2, IL5, IL10, IL13, and IFNG) upon ligand binding. DNAM-1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived DNAM-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of DNAM-1 Protein, Human (Biotinylated, HEK293, His-Avi) is 229 a.a., with molecular weight of 48-68 kDa.
  • HY-P78201
    P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi)

    FLJ45155; GMP140; GRMP; PADGEM; PSEL; P-Selectin; SELP; CD62P; CD62; LECAM3

    Human HEK293
    P-selectin, a Ca(2+)-dependent receptor on myeloid cells, crucially binds to sialyl-Lewis X on neutrophils and monocytes, facilitating the interaction of activated endothelial cells or platelets with leukocytes. This engagement, primarily with SELPLG/PSGL1 and PODXL2, is vital for the rapid rolling of leukocytes during early inflammation. P-selectin's interactions with SNX17 further mediate neutrophil adhesion and rolling, dependent on the sialyl-Lewis X epitope and specific tyrosine sulfation on SELPLG. P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived P-Selectin protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi) is 730 a.a., with molecular weight of 115-140 kDa.
  • HY-P78372
    Nectin-2/CD112 Protein, Human (329a.a, HEK293, Fc)

    CD112; MPH; Nectin2; PRR2; PVRL2; HVEB; PVRR2

    Human HEK293
    Nectin-2/CD112 protein has dual roles in T-cell signaling: as a costimulator with CD226, promoting proliferation and cytokine production, and as a coinhibitor with PVRIG, inhibiting proliferation. It also acts as a cell adhesion protein and a receptor for certain viruses. Nectin-2/CD112 Protein, Human (329a.a, HEK293, Fc) is the recombinant human-derived Nectin-2/CD112 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Nectin-2/CD112 Protein, Human (329a.a, HEK293, Fc) is 329 a.a., with molecular weight of 70-80 kDa.
Cat. No. Product Name Effect Purity