1. Recombinant Proteins
  2. Enzymes & Regulators
  3. Cyclin-Dependent Kinase Inhibitor Proteins

Cyclin-Dependent Kinase Inhibitor Proteins

Cat. No. Product Name / Synonyms Species Source
  • HY-P72785
    CDKN2A Protein, Human

    Cyclin-dependent kinase inhibitor 2A; CDK4I; MTS-1; p16INK4A

    Human E. coli
    CDKN2A Protein, a potent negative regulator of cell proliferation, forms strong interactions with CDK4 and CDK6, hindering their association with cyclins D and retinoblastoma protein phosphorylation. Acting in a heterodimeric manner, predominantly with CDK6, CDKN2A inhibits cyclin D-CDK4 kinase activity and interacts with ISCO2, contributing to its cell cycle regulatory role. CDKN2A Protein, Human is the recombinant human-derived CDKN2A protein, expressed by E. coli, with tag free. The total length of CDKN2A Protein, Human is 155 a.a., with molecular weight of ~19.12 kDa.
  • HY-P74659
    p19INK4d Protein, Human (His)

    Cyclin-dependent kinase 4 inhibitor D; p19-INK4d; CDKN2D

    Human E. coli
    The p19INK4d protein, a potent inhibitor, strongly interacts with CDK4 and CDK6, effectively impeding their activity. Specifically interacting with CDK6, p19INK4d reinforces its role as a regulator of cyclin-dependent kinase activity. This crucial role in cell cycle regulation involves restraining CDK4 and CDK6 functions, contributing to the modulation of key cellular processes. p19INK4d Protein, Human (GST) is the recombinant human-derived p19INK4d protein, expressed by E. coli , with N-GST labeled tag. The total length of p19INK4d Protein, Human (GST) is 166 a.a., with molecular weight of ~46 kDa.
  • HY-P70034
    CDKN2C Protein, Human (His)

    rHuCyclin-dependent kinase 4 inhibitor C/CDKN2C, His; Cyclin-Dependent Kinase 4 Inhibitor C; Cyclin-Dependent Kinase 6 Inhibitor; p18-INK4c; p18-INK6; CDKN2C; CDKN6

    Human E. coli
    The CDKN2C protein (also known as p18) interacts strongly with CDK6 and weakly with CDK4. Its functional effects inhibit cell growth and proliferation and are significantly related to the presence of endogenous retinoblastoma protein RB. CDKN2C Protein, Human (His) is the recombinant human-derived CDKN2C protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDKN2C Protein, Human (His) is 168 a.a., with molecular weight of ~17.0 kDa.
  • HY-P70037
    CDKN1B Protein, Human (His)

    rHuCyclin-dependent kinase inhibitor 1B/CDKN1B, His; Cyclin-Dependent Kinase Inhibitor 1B; Cyclin-Dependent Kinase Inhibitor p27; p27Kip1; CDKN1B; KIP1

    Human E. coli
    The CDKN1B protein is a key cell cycle regulator that inhibits CDK2 when bound to cyclin A, thereby inhibiting G1 phase progression. It exhibits significant inhibitory effects on cyclin E- and cyclin A-CDK2 complexes. CDKN1B Protein, Human (His) is the recombinant human-derived CDKN1B protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDKN1B Protein, Human (His) is 198 a.a., with molecular weight of ~30.0 kDa.
Cat. No. Product Name Effect Purity