1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. CSF & Receptors
  4. M-CSF

Macrophage colony-stimulating factor (M-CSF), also known as colony-stimulating factor-1 (CSF-1), is a hemopoietic growth factor that regulates the survival, proliferation, differentiation and function of the cells of the mononuclear phagocyte lineage. M-CSF is produced by a variety of cell types and acts both locally and humorally in an autocrine and paracrine manner. Through differential mRNA splicing and posttranslational proteolytic processing and modification, M-CSF is expressed in three biologically-active isoforms: a secreted glycoprotein; a secreted proteoglycan; and a membrane spanning cell-surface glycoprotein.

Cat. No. Product Name / Synonyms Species Source
  • HY-P7085A
    M-CSF Protein, Mouse (CHO)

    rMuM-CSF; CSF-1; MGI-IM

    Mouse CHO
    M-CSF Protein, Mouse (CHO) is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.
  • HY-P7050A
    M-CSF Protein, Human (CHO)

    rHuM-CSF; CSF-1; MGI-IM

    Human CHO
    M-CSF Protein, Human (CHO) is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.
  • HY-P70553
    M-CSF Protein, Mouse (HEK293)

    Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm

    Mouse HEK293
    M-CSF Protein, Mouse (HEK293) is a pro-inflammatory cytokine which binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts.
  • HY-P73827
    M-CSF Protein, Human (HEK293, His)

    Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; Lanimostim

    Human HEK293
    The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (HEK293, His) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-His labeled tag. The total length of M-CSF Protein, Human (HEK293, His) is 158 a.a., with molecular weight of 27-32 kDa.
  • HY-P700137AF
    Animal-Free M-CSF Protein, Human (His)

    Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; MCSF; Lanimostim; CSF1

    Human E. coli
    The M-CSF protein regulates macrophage production, differentiation, and function. It exists as an active disulfide-linked homodimer outside of cells, generated through proteolytic cleavage. It may also play a role in placental development. Alternative splicing produces multiple transcript variants. M-CSF is widely expressed in tissues such as placenta, spleen, and 25 other tissues. Animal-Free M-CSF Protein, Human (His) is the recombinant human-derived animal-FreeM-CSF protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free M-CSF Protein, Human (His) is 232 a.a., with molecular weight of ~13.34 kDa.
  • HY-P700222AF
    Animal-Free M-CSF Protein, Mouse (His)

    rMuM-CSF; CSF-1; MGI-IM

    Mouse E. coli
    The M-CSF protein is a key orchestrator in regulating the survival, proliferation, and differentiation of hematopoietic precursor cells, particularly mononuclear phagocytes, including macrophages and monocytes. It actively promotes the release of pro-inflammatory chemokines, thereby playing a key role in innate immunity and inflammatory processes. Animal-Free M-CSF Protein, Mouse (His) is the recombinant mouse-derived animal-FreeM-CSF protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free M-CSF Protein, Mouse (His) is 155 a.a., with molecular weight of ~19.02 kDa.
  • HY-P7085
    M-CSF Protein, Mouse

    rMuM-CSF; CSF-1; MGI-IM

    Mouse E. coli
    M-CSF Protein, Mouse is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.
  • HY-P7050
    M-CSF Protein, Human

    rHuM-CSF; CSF-1; MGI-IM

    Human E. coli
    M-CSF Protein, Human is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.
  • HY-P7247
    M-CSF Protein, Rat (CHO)

    rRtM-CSF; CSF1; MCSF

    Rat CHO
    M-CSF Protein, Rat (CHO) is a pro-inflammatory cytokine which binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts.
  • HY-P70488
    M-CSF Protein, Human (223a.a, HEK293, His)

    Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; MCSF; Lanimostim; CSF1

    Human HEK293
    The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (223a.a, HEK293, His) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of M-CSF Protein, Human (223a.a, HEK293, His) is 223 a.a., with molecular weight of ~41.0 kDa.
  • HY-P73829
    M-CSF Protein, Human (HEK293, Fc)

    Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; Lanimostim

    Human HEK293
    The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (HEK293, Fc) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of M-CSF Protein, Human (HEK293, Fc) is 223 a.a., with molecular weight of ~51.9 kDa.
  • HY-P70263A
    M-CSF Protein, Mouse (HEK293, C-His)

    rMuMacrophage colony-stimulating factor 1/M-CSF, His; Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm

    Mouse HEK293
    The M-CSF protein is a key orchestrator in regulating the survival, proliferation, and differentiation of hematopoietic precursor cells, particularly mononuclear phagocytes, including macrophages and monocytes. It actively promotes the release of pro-inflammatory chemokines, thereby playing a key role in innate immunity and inflammatory processes. M-CSF Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived M-CSF protein, expressed by HEK293 , with C-His labeled tag. The total length of M-CSF Protein, Mouse (HEK293, C-His) is 230 a.a., with molecular weight (glycosylation form) of ~38-55 kDa.
  • HY-P70493
    M-CSF Protein, Rat (HEK293)

    Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1

    Rat HEK293
    The M-CSF protein regulates hematopoietic precursor cells, promoting their survival, proliferation, and differentiation. M-CSF Protein, Rat (HEK293) is the recombinant rat-derived M-CSF protein, expressed by HEK293 , with tag free. The total length of M-CSF Protein, Rat (HEK293) is 222 a.a., with molecular weight of ~46.0 kDa.
  • HY-P7386
    M-CSF Protein, Rat

    rRtM-CSF; CSF-1; M-CSF

    Rat E. coli
    M-CSF Protein, Rat is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.
  • HY-P73831
    M-CSF Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)

    Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; Lanimostim

    Rhesus Macaque; Cynomolgus HEK293
    The M-CSF protein regulates hematopoietic precursor cells, promoting their survival, proliferation, and differentiation. M-CSF Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque, cynomolgus-derived M-CSF protein, expressed by HEK293 , with C-hFc labeled tag. The total length of M-CSF Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is 190 a.a., with molecular weight of ~45.1 kDa.
  • HY-P73288
    M-CSF Protein, Mouse (HEK293, Tag Free)

    Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; Lanimostim

    Mouse HEK293
    The M-CSF protein is a key orchestrator in regulating the survival, proliferation, and differentiation of hematopoietic precursor cells, particularly mononuclear phagocytes, including macrophages and monocytes. It actively promotes the release of pro-inflammatory chemokines, thereby playing a key role in innate immunity and inflammatory processes. M-CSF Protein, Mouse (HEK293, Tag Free) is the recombinant mouse-derived M-CSF protein, expressed by HEK293 , with tag free. The total length of M-CSF Protein, Mouse (HEK293, Tag Free) is 230 a.a., with molecular weight of ~45 kDa.
  • HY-P73287
    M-CSF Protein, Human (Biotinylated, HEK293, His)

    Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; Lanimostim

    Human HEK293
    The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-His labeled tag. The total length of M-CSF Protein, Human (Biotinylated, HEK293, His) is 158 a.a., with molecular weight of 27-32 kDa.
  • HY-P78427
    M-CSF Protein, Human (HEK293, His-Avi)

    CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim

    Human HEK293
    The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (HEK293, His-Avi) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of M-CSF Protein, Human (HEK293, His-Avi) is 158 a.a., with molecular weight of 28-34 kDa.
  • HY-P700788
    M-CSF Protein, Human (Biotinylated, HEK293, C-His-Avi)

    CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim

    Human HEK293
    The M-CSF protein is an important cytokine that modulates hematopoietic precursor cells, especially mononuclear phagocytes, affecting innate immunity and inflammation through the release of proinflammatory chemokines. It is essential for osteoclast proliferation and regulates bone resorption, bone development and fertility. M-CSF Protein, Human (Biotinylated, HEK293, C-His-Avi) is the recombinant human-derived M-CSF protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of M-CSF Protein, Human (Biotinylated, HEK293, C-His-Avi) is 158 a.a., with molecular weight of 27-37 kDa.
  • HY-P701101
    M-CSF Protein, Human (CHO,Tag free)

    rHuM-CSF; CSF-1; MGI-IM

    Human CHO
    M-CSF Protein, Human (CHO) is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.
Cat. No. Product Name Effect Purity