1. Stem Cell/Wnt
  2. Hippo (MST)

Hippo (MST)

Hippo signaling pathway, also known as the Salvador/Warts/Hippo (SWH) pathway, controls organ size in animals through the regulation of cell proliferationand apoptosis. The Hippo pathway consists of a core kinase cascade in which Hpo phosphorylates the protein kinase Warts (Wts) Hpo (MST1/2 in mammals) is a member of the Ste-20 family of protein kinases. This highly conserved group of serine/threonine kinases regulates several cellular processes, including cell proliferation, apoptosis, and various stress responses.

Hippo (MST) Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-100526
    XMU-MP-1 Inhibitor 99.34%
    XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50 values of 71.1 and 38.1 nM against MST1 and MST2.