1. Signaling Pathways
  2. Stem Cell/Wnt
  3. Oct3/4


Oct3/4 (also known as POU5F1 and Oct4) is regarded as one of the key regulators of pluripotency. Oct-4 is a homeodomain transcription factor of the POU family. This protein is critically involved in the self-renewal of undifferentiated embryonic stem cells. it is frequently used as a marker for undifferentiated cells. Oct-4 expression must be closely regulated; too much or too little will cause differentiation of the cells.

Oct3/4 Related Products (5):

Cat. No. Product Name Effect Purity
  • HY-12303
    Activator 99.12%
    OAC1 is a potent Oct4 activator. OAC1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. OAC1 activates OCT4 through upregulation of HOXB4 expression. OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and Tet1. OAC1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time.
  • HY-12884
    Activator 99.57%
    OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter.
  • HY-18772
    Activator 99.42%
    O4I2 is a potent Oct3/4 inducer. O4I2 induces the expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1.
  • HY-18773
    Activator 98.04%
    Oct3/4-inducer-1 (compound 2) is a potent Oct3/4 inducer. Oct3/4-inducer-1 promotes expression and stabilization of Oct3/4, and enhances its transcriptional activity in diverse human somatic cells.
  • HY-18771
    O4I1 is as a potent Oct3/4 inducer.