1. Recombinant Proteins
  2. CD Antigens
  3. Endothelial cell CD Proteins

Endothelial cell CD Proteins

The cluster of differentiation (CD) antigens is a protocol used for the identification and investigation of cell surface molecules present on leukocytes. Some CD proteins often act as cell-cell or cell-matrix adhesion molecules, cytokine receptors, ion pores, or nutrient transporters. CD proteins play a variety of roles in immune system function. Endothelial cells form the linings of the blood vessels and regulates exchanges between the bloodstream and the surrounding tissues. Endothelial cells are generally identified through the presence of specific surface biomarkers, particularly CD31 and CD34. Additionally, CD146 is expressed on endothelial cells that is involved in the organization of cohesive contacts between adjacent cells.

Cat. No. Product Name / Synonyms Species Source
  • HY-P71963
    IL-17RA Protein, Human (HEK293, hFc)

    CANDF5; CD217; CD217 antigen; CDw217; CTLA8; HIL 17R; hIL17R; I17RA_HUMAN; IL 17 receptor A; IL 17 receptor; IL 17RA; IL-17 receptor A; IL-17RA; IL17; IL17A receptor; IL17R; IL17RA; IMD51; Interleukin 17 receptor A; Interleukin-17 receptor A; MGC10262

    Human HEK293
    IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (HEK 293, hFc) is produced in HEK293 cells with a C-Terminal hFc-tag. It consists of 288 amino acids (L33-W320).
  • HY-P72359
    CD47 Protein, Human (Biotinylated, HEK293, Avi-His)

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; IAP; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is 121 a.a., with molecular weight of 30-55 kDa.
  • HY-P73309
    Neuropilin-1 Protein, Human (Biotinylated, HEK293, His-Avi, solution)

    Neuropilin-1, His; CD304; NRP1; NRPNP1; VEGF165R; BDCA4

    Human HEK293
    Neuropilin-1 Protein plays a significant role by binding to VEGF-165, potentially inhibiting its cellular binding and inducing apoptosis. This dual functionality suggests its role in regulating VEGF-mediated processes. Interactions with semaphorin family members highlight its versatile ligand-binding capability. Neuropilin-1's expression adversely affects blood vessel number and integrity, suggesting a potential role in angiogenesis. Its diverse interactions underscore its importance in orchestrating complex cellular processes and implications in angiogenesis and apoptotic pathways. Neuropilin-1 Protein, Human (Biotinylated, HEK293, His-Avi, solution) is the recombinant human-derived Neuropilin-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag and V179A mutation. The total length of Neuropilin-1 Protein, Human (Biotinylated, HEK293, His-Avi, solution) is 623 a.a., with molecular weight of ~73.1 kDa.
  • HY-P72824
    Aminopeptidase A Protein, Human (sf9, His)

    Glutamyl aminopeptidase; EAP; AP-A; CD249; ENPEP

    Human Sf9 insect cells
    Aminopeptidase A protein has calcium-regulating activity and plays a key role in central hypertension by preferentially cleaving N-terminal acidic residues, including angiotensin II. The specificity of this enzyme highlights its involvement in the regulation of blood pressure-related peptides, suggesting potential implications for the physiological mechanisms of hypertension. Aminopeptidase A Protein, Human (sf9, His) is the recombinant human-derived Aminopeptidase A protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Aminopeptidase A Protein, Human (sf9, His) is 917 a.a., with molecular weight of ~115.5 kDa.
  • HY-P70010
    CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His)

    rHu5'-nucleotidase/CD73, His; 5'-Nucleotidase; 5'-NT; Ecto-5'-Nucleotidase; CD73; NT5E; NT5; NTE

    Human HEK293
    CD73/5'-Nucleotidase Protein hydrolyzes nucleotide monophosphates, favoring AMP as the primary substrate and showing a preference for ribonucleotide monophosphates. It releases inorganic phosphate and the corresponding nucleoside. CD73 also acts on other substrates, including IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD, and NMN. CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) is the recombinant human-derived CD73/5'-Nucleotidase protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD73/5'-Nucleotidase Protein, Human (521a.a, HEK293, His) is 521 a.a., with molecular weight of ~62.0 kDa.
  • HY-P70325
    IL-4R alpha/CD124 Protein, Human (HEK293, mFc)

    rHuInterleukin-4 receptor subunit alpha/IL-4 RA, mFc; Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA

    Human HEK293
    IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (M26-Q231) is produced in HEK293 cells with a C-Terminal mFc-tag.
  • HY-P70710
    IL-4R alpha/CD124 Protein, Human (HEK293, His)

    Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA

    Human HEK293
    IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (M26-H232) is produced in HEK293 cells with a C-Terminal His-tag.
  • HY-P70712
    IL-4R alpha/CD124 Protein, Human (HEK293, Fc)

    Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA

    Human HEK293
    IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells. IL-4R alpha/CD124, Human (M26-Q231) is produced in HEK293 cells with a C-Terminal hFc-tag.
  • HY-P70820
    CD47 Protein, Mouse (HEK293, His)

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6

    Mouse HEK293
    CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-6*His labeled tag. The total length of CD47 Protein, Mouse (HEK293, His) is 140 a.a., with molecular weight of 30-60 kDa.
  • HY-P72374
    HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc-Avi)

    Proto-oncogene Neu; Tyrosine kinase-type cell surface receptor ERBB2; MLN19; NGL; TKR1

    Human HEK293
    The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of HER2/CD340 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 630 a.a., with molecular weight of 120-140 kDa.
  • HY-P72892
    CD31/PECAM-1 Protein, Human

    Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; PECA1; CD31

    Human HEK293
    CD31/PECAM-1 Protein, a pivotal cell adhesion molecule, is essential for leukocyte transendothelial migration (TEM) in most inflammatory conditions. PECAM1 modulates bradykinin receptor BDKRB2 activation and regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells. Signaling through PECAM-1 leads to the activation of neutrophils, monocytes and leukocytes. CD31/PECAM-1 Protein, Human is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with tag free. The total length of CD31/PECAM-1 Protein, Human is 574 a.a., with molecular weight of ~115 kDa.
  • HY-P72895
    CD36 Protein, Mouse (HEK293, His)

    Glycoprotein IIIb; GPIIIB; PAS IV; PAS-4; Platelet glycoprotein 4; GPIV; CD36

    Mouse HEK293
    CD36 is the subject in the following active sentence patterns mentioned in the paragraph: CD36 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD36 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD36 Protein, Mouse (HEK293, His) is 410 a.a., with molecular weight of 75-90 kDa.
  • HY-P72917
    CD47 Protein, Human (HEK293)

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (HEK293) is the recombinant human-derived CD47 protein, expressed by HEK293 , with tag free. The total length of CD47 Protein, Human (HEK293) is 121 a.a., with molecular weight of 35-48 kDa.
  • HY-P72918
    CD47 Protein, Mouse (140a.a, HEK293, His)

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Mouse HEK293
    CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (140a.a, HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-His labeled tag. The total length of CD47 Protein, Mouse (140a.a, HEK293, His) is 122 a.a., with molecular weight of 34-44 kDa.
  • HY-P72921
    ICAM-3/CD50 Protein, Human (HEK293, His)

    Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD50

    Human HEK293
    The ICAM-3/CD50 protein acts as a ligand for the leukocyte adhesion protein LFA-1 and integrin α-D/β-2, suggesting involvement in cell adhesion. ICAM-3 cooperates with integrin α-L/β-2 to facilitate phagocytosis of apoptotic neutrophils, suggesting a role in immune response regulation and apoptotic cell clearance. ICAM-3/CD50 Protein, Human (HEK293, His) is the recombinant human-derived ICAM-3/CD50 protein, expressed by HEK293 , with C-His labeled tag. The total length of ICAM-3/CD50 Protein, Human (HEK293, His) is 456 a.a., with molecular weight of 100-120 kDa.
  • HY-P73083
    GM-CSF R alpha Protein, Human (HEK293, Fc)

    Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GMR-alpha; CD116; CSF2RA; CSF2R; CSF2RY

    Human HEK293
    GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2. GM-CSF R alpha binds to the cytokine with high specificity and low affinity. GM-CSF R alpha binds to GM-CSF and induces cell differentiation. GM-CSF R alpha monoclonal antibody decreases GM-CSFRα expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA). GM-CSF R alpha Protein, Human (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 320 amino acids (M1-G320) and is produced in HEK293 cells.
  • HY-P73094
    HER2/CD340 Protein, Human (HEK293)

    Receptor tyrosine-protein kinase erbB-2; MLN 19; CD340; ERBB2; HER2; NEU; NGL

    Human HEK293
    The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization. HER2/CD340 Protein, Human (HEK293) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293 , with tag free. The total length of HER2/CD340 Protein, Human (HEK293) is 630 a.a., with molecular weight of 100-110 kDa.
  • HY-P73307
    Nectin-2/CD112 Protein, Human (HEK293)

    Nectin-2; CD112; NECTIN2; PVRL2; HVEB; PRR2

    Human HEK293
    Nectin-2/CD112 protein has dual roles in T-cell signaling: as a costimulator with CD226, promoting proliferation and cytokine production, and as a coinhibitor with PVRIG, inhibiting proliferation. It also acts as a cell adhesion protein and a receptor for certain viruses. Nectin-2/CD112 Protein, Human (HEK293) is the recombinant human-derived Nectin-2/CD112 protein, expressed by HEK293 , with tag free. The total length of Nectin-2/CD112 Protein, Human (HEK293) is 329 a.a., with molecular weight of 45-55 kDa.
  • HY-P7336
    CD47 Protein, Human (HEK293, His)

    rHuCD47, His; CD47; MER6; IAP; OA3

    Human HEK293
    CD47 Protein, Human (HEK293, His) is a polypeptide chain with His tag produced in HEK293 cells. CD47 is a prominent target in cancer immunotherapy.
  • HY-P73468
    VCAM-1/CD106 Protein, Human (HEK293, Fc)

    Vascular Cell Adhesion Protein 1; VCAM-1; INCAM-100; CD106; L1CAM

    Human HEK293
    VCAM-1/CD106 proteins expressed on endothelial cells critically regulate leukocyte adhesion through integrin interactions, initiating calcium channel activation and RAC1-mediated transendothelial migration during inflammation. VCAM-1/CD106 Protein, Human (HEK293, Fc) is the recombinant human-derived VCAM-1/CD106 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VCAM-1/CD106 Protein, Human (HEK293, Fc) is 673 a.a., with molecular weight of 110-150 kDa.
Cat. No. Product Name Effect Purity