2. Recombinant Proteins
  3. Kinases
  4. CMGC
  5. MAPK

MAPK

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Cat. No. Product Name / Synonyms Species Source Image
  • HY-P73335
    p38 alpha/MAPK14 Protein, Human (Active, sf9, His)

    Mitogen-activated protein kinase 14; MAPK 14; CSBP; MXI2; SAPK2A

    		Human Sf9 insect cells
    The p38 α/MAPK14 protein is an important serine/threonine kinase in the MAP kinase pathway. It can respond to stimuli such as cytokines or stress and directly activate transcription factors. In this cascade, p38 MAPK each phosphorylates approximately 200 to 300 substrates, including the downstream kinases RPS6KA5/MSK1 and RPS6KA4/MSK2, which are critical for immediate early gene induction. p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) is the recombinant human-derived p38 alpha/MAPK14 protein, expressed by Sf9 insect cells , with N-His labeled tag.
  • HY-P73848
    JNK1 Protein, Human (Inactive, sf9, GST)

    Mitogen-activated protein kinase 8; MAPK 8; JNK-46; JNK1; PRKM8

    		Human Sf9 insect cells
    JNK1 is a multifunctional serine/threonine protein kinase that complexly regulates multiple cellular processes, including cell proliferation, apoptosis, and differentiation. JNK1 is activated by MAP2K4/MKK4 and MAP2K7/MKK7, phosphorylates AP-1 components, and affects transcriptional activity. JNK1 Protein, Human (sf9, GST) is the recombinant human-derived JNK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag.
  • HY-P75223
    MAPK1/ERK2 Protein, Human (Active, sf9, His)

    Mitogen-activated protein kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK

    		Human Sf9 insect cells
    ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. MAPK1/ERK2 Protein, Human (sf9, His) is the recombinant human-derived ERK2 protein, expressed by Sf9 insect cells , with C-His labeled tag.
    (1)
  • HY-P76532
    p38 gamma/MAPK12 Protein, Human (sf9)

    Mitogen-activated protein kinase 12; Extracellular signal-regulated kinase 6; ERK-6; SAPK3

    		Human Sf9 insect cells
    The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells, with tag free.
  • HY-P701678
    ERK1 Protein, Human (Active, GST)

    MAPK3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1

    		Human E. coli
    ERK1 protein is an important serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 to activate the MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway plays a key role in cell growth, adhesion, survival, and differentiation. ERK1 Protein, Human (GST) is the recombinant human-derived ERK1 protein, expressed by E. coli , with N-GST labeled tag.
  • HY-P702735
    MAPK1/ERK2 Protein, Human (Active, Flag-His)

    MAPK1; mitogen-activated protein kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41mapk; ERK-2; MAPK 2; p42-MAPK; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK

    		Human E. coli
    ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. MAPK1 Protein, Human (Active, Flag, His) is the recombinant human-derived MAPK1, expressed by E. coli, with N-His, N-Flag labeled tag.
  • HY-P73334
    p38 delta/MAPK13 Protein, Human (Active, sf9, GST)

    Mitogen-activated protein kinase 13; MAPK 13; PRKM13; SAPK4

    		Human Sf9 insect cells
    The p38 delta/MAPK13 protein is an important serine/threonine kinase in the MAP kinase pathway. It coordinates cellular responses to stimuli such as cytokines or stress and directly activates the transcription factors ELK1 and ATF2. In this cascade, p38 MAPK (including MAPK13) each phosphorylates approximately 200 to 300 substrates. p38 delta/MAPK13 Protein, Human (sf9, GST) is the recombinant human-derived p38 delta/MAPK13 protein, expressed by Sf9 insect cells , with N-GST labeled tag.
  • HY-P76517
    NLK/Nemo Like Kinase Protein, Human (Active, sf9, His-GST)

    Serine/threonine-protein kinase NLK; Nemo-like kinase; NLK

    		Human Sf9 insect cells
    NLK/Nemo-like kinase protein is a key serine/threonine protein kinase that directs cell fate through multiple regulatory effects. As a non-canonical Wnt pathway effector, NLK affects transcription factors downstream of WNT5A, MAP3K7/TAK1, and HIPK2. NLK/Nemo Like Kinase Protein, Human (sf9, His-GST) is the recombinant human-derived NLK/Nemo Like Kinase protein, expressed by Sf9 insect cells , with N-GST, N-His labeled tag.
  • HY-P76533
    p38 gamma/MAPK12 Protein, Human (sf9, His-GST)

    Mitogen-activated protein kinase 12; Extracellular signal-regulated kinase 6; ERK-6; SAPK3

    		Human Sf9 insect cells
    The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9, His-GST) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
  • HY-P701679
    ERK3 Protein, Human (Inactive, L290V)

    MAPK6; Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK

    		Human E. coli
    ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (L290V) is the recombinant human-derived ERK3 protein, expressed by E. coli , with tag free.
  • HY-P701680
    ERK3 Protein, Human (Inactive, L290V, His)

    MAPK6; Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK

    		Human E. coli
    ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (L290V, His) is the recombinant human-derived ERK3 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P701730
    P38β Protein, Human (Inactive, sf9)

    MAPK11; Mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; Mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2

    		Human Sf9 insect cells
    The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (sf9) is the recombinant human-derived P38β protein, expressed by sf9 insect cells , with tag free.
  • HY-P701731
    P38β Protein, Human (Inactive, sf9, GST)

    MAPK11; Mitogen-activated protein kinase 11; MAP kinase 11; MAPK 11; Mitogen-activated protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated protein kinase 2b; SAPK2b; p38-2

    		Human Sf9 insect cells
    The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (sf9, GST) is the recombinant human-derived P38β protein, expressed by sf9 insect cells , with N-GST labeled tag.
  • HY-P701790
    JNK3 Protein, Human (364a.a, His)

    MAPK10; Mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3

    		Human E. coli
    JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human is the recombinant human-derived JNK3 protein, expressed by E. coli , with tag free.
  • HY-P701791
    JNK3 Protein, Human (His)

    MAPK10; Mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3

    		Human E. coli
    JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human (His) is the recombinant human-derived JNK3 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P701803
    MAPK4 Protein, Human (sf9, His, GST)

    MAPK4; Mitogen-activated protein kinase 4; MAP kinase 4; MAPK 4; Extracellular signal-regulated kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK

    		Human Sf9 insect cells
    MAPK4, an atypical MAPK protein, phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5, forming a complex with intricate phosphorylation events. Interaction with MAPKAPK5 leads to ERK3/MAPK6 phosphorylation at Ser-189, activating MAPKAPK5, which reciprocally phosphorylates ERK3/MAPK6. The specific cellular role of this interplay, while unclear, suggests ERK3's potential involvement in promoting entry into the cell cycle. MAPK4 Protein, Human (sf9, His, GST) is the recombinant human-derived MAPK4 protein, expressed by sf9 insect cells , with N-8*His, N-GST labeled tag.
  • HY-P702934
    MAPK15 Protein, Human (Active, sf9, GST, Strep II)

    Mitogen-activated protein kinase 15 Curated; MAPK 15; Extracellular signal-regulated kinase 7 (ERK-7); Extracellular signal-regulated kinase 8 (ERK-8); MAPK15 Imported; ERK7 By similarity

    		Human Sf9 insect cells
    MAPK15 Protein, Human (Active, sf9, GST, Strep II) is the recombinant human-derived MAPK15, expressed by Sf9 insect cells , with C-Strep II, N-GST labeled tag.
  • HY-P703020
    JNK1 Protein, Mouse (GST)

    Jnk1; Prkm8

    		Mouse E. coli
    JNK1 Protein, Mouse (Inactive, GST) is the recombinant mouse-derived JNK1, expressed by E. coli , with GST labeled tag. ,
  • HY-P703179
    MAPK7 Protein, Human

    BMK1; ERK5; PRKM7

    		Human E. coli
    MAPK7 Protein, Human is the recombinant human-derived MAPK7, expressed by E. coli , with tag Free labeled tag. ,
  • HY-P705577
    MAPK8/JNK1 Protein, Human

    Mitogen-activated protein kinase 8; MAP kinase 8; JNK-46; Stress-activated protein kinase 1c (SAPK1c); c-Jun N-terminal kinase 1; JNK1; PRKM8; SAPK1; SAPK1C; EC:2.7.11.24

    		Human E. coli
Cat. No. Product Name Effect Purity