Phospholipids

DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.

DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA.

DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.

1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.

Phosphatidylcholines,soya is a phosphatidylcholine from soybean used in the preparation of liposomes. Phosphatidylcholines,soya can be used as a vehicle in animal agent administration.

DMPG (L-α-Dimyristoylphosphatidylglycerol; 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol) is a phospholipid that can be used for preparing formulations such as liposomes or gels. DMPG can be used in the research of drug delivery.

16:0 Ptd thioethanol sodium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers.

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems.

1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (18:1 PA sodium salt) is an anionic lipid that can be used to prepare liposomes, micelles and artificial membranes.

1-Palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC) is an abundant lysophosphatidylcholine. 1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity. 1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis.

Phosphatidylcholines, egg are a type of phosphatidylcholine that can be isolated and extracted from eggs, primarily present in egg yolks. As a major phospholipid component of cell membranes, Phosphatidylcholines, egg play a key role in providing nutrition and protection to the body. Phosphatidylcholines, egg can inhibit oxidative stress and neurotoxicity, exerting neuroprotective effects. Additionally, Phosphatidylcholines, egg can suppress the lymphatic absorption of cholesterol in the intestine and are also used in research on intestinal lipid absorption.

Colfosceril miristate (DMPC) is a synthetic phospholipid. Colfosceril miristate has antiproliferative effects on various tumors. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery.

Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). Low plasma Lysophosphatidylcholine 18:2 also has been shown to predict impaired glucose tolerance, insulin resistance, type 2 diabetes, coronary artery disease, and memory impairment.

Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity. Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT).

1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells.

DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties.

Perifosine is an oral Akt inhibitor which inhibits proliferation of different tumor cell lines with IC₅₀s of 0.6-8.9 μM.

1-Oleoyl-sn-glycero-3-phosphocholine (18:1 Lyso PC), a lysophospholipid, is a GPR82 inhibitor. 1-Oleoyl-sn-glycero-3-phosphocholine abrogates constitutive Gi-coupled GPR82 activity, shifts active/inactive equilibrium to inactive, suppresses Gi protein activation, increases cAMP production, and decreases GTPγS binding to Gαi proteins. 1-Oleoyl-sn-glycero-3-phosphocholine contributes to adipocyte lipolysis regulation.1-Oleoyl-sn-glycero-3-phosphocholine exhibits reduced serum levels in mouse models of steatohepatitis, linked to hepatic Lpcat 1-4 up-regulation.

LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect.