1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. HDAC
  4. HDAC3 Inhibitors

HDAC3 Inhibitors

HDAC

HDAC1

HDAC2

HDAC3

HDAC4

HDAC5

HDAC6

HDAC7

HDAC8

HDAC9

HDAC10

HDAC11

HD1

HD2

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform HDAC3 together.

Please try each isoform separately.

HDAC3 Specific Inhibitors
Product Name HDAC3 HDAC HDAC1 HDAC2 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2 HDAC3 Selectivity Purity
RGFP966
HDAC3, IC50: 80 nM
                          Selective Inhibitor 98.99%
SR-4370
HDAC3, IC50: 6 nM
 
HDAC1, IC50: 130 nM
HDAC2, IC50: 580 nM
   
HDAC6, IC50: 3400 nM
 
HDAC8, IC50: 2300 nM
          Selective Inhibitor 98.33%
Crotonoside
HDAC3
         
HDAC6
              Selective Inhibitor
Entinostat
HDAC3, IC50: 248 nM
 
HDAC1, IC50: 243 nM
HDAC2, IC50: 453 nM
                    Pan Inhibitor 99.65%
SW-100
HDAC3, IC50: 29.5 μM
 
HDAC1, IC50: 5.23 μM
HDAC2, IC50: 32.8 μM
HDAC4, IC50: 10.9 μM
HDAC5, IC50: 4.07 μM
HDAC6, IC50: 2.3 nM
HDAC7, IC50: 4.55 μM
HDAC8, IC50: 3.72 μM
HDAC9, IC50: 3.46 μM
HDAC10, IC50: 26.2 μM
HDAC11, IC50: 5.72 μM
    Pan Inhibitor 99.92%
Ricolinostat
HDAC3, IC50: 51 nM
 
HDAC1, IC50: 58 nM
HDAC2, IC50: 48 nM
HDAC4, IC50: 7000 nM
HDAC5, IC50: 5000 nM
HDAC6, IC50: 4.7 nM
HDAC7, IC50: 1400 nM
HDAC8, IC50: 100 nM
          Pan Inhibitor 99.70%
Mocetinostat
HDAC3, IC50: 1.66 μM
 
HDAC1, IC50: 0.15 μM
HDAC2, IC50: 0.29 μM
             
HDAC11, IC50: 0.59 μM
    Pan Inhibitor 99.81%
Fimepinostat
HDAC3, IC50: 1.8 nM
 
HDAC1, IC50: 1.7 nM
HDAC2, IC50: 5 nM
HDAC4, IC50: 409 nM
HDAC5, IC50: 674 nM
HDAC6, IC50: 27 nM
HDAC7, IC50: 426 nM
HDAC8, IC50: 191 nM
HDAC9, IC50: 554 nM
HDAC10, IC50: 2.8 nM
HDAC11, IC50: 5.4 nM
    Pan Inhibitor 99.95%
Tubacin
HDAC3, IC50: 1.27 μM
 
HDAC1, IC50: 1.40 μM
HDAC2, IC50: 6.27 μM
HDAC4, IC50: 17.30 μM
HDAC5, IC50: 3.35 μM
HDAC6, IC50: 4 nM
HDAC7, IC50: 9.70 μM
HDAC8, IC50: 1.27 μM
HDAC9, IC50: 4.31 μM
HDAC10, IC50: 3.71 μM
HDAC11, IC50: 3.79 μM
    Pan Inhibitor 98.87%
Tacedinaline
HD3, IC50: 1.2 μM
 
HD1, IC50: 0.9 μM
HD2, IC50: 0.9 μM
                    Pan Inhibitor 99.51%
ACY-738
HDAC3, IC50: 218 nM
 
HDAC1, IC50: 94 nM
HDAC2, IC50: 128 nM
   
HDAC6, IC50: 1.7 nM
              Pan Inhibitor 99.94%
Nexturastat A
HDAC3, IC50: 6.68 μM
 
HDAC1, IC50: 3.02 μM
HDAC2, IC50: 6.92 μM
HDAC4, IC50: 9.39 μM
HDAC5, IC50: 11.7 μM
HDAC6, IC50: 5.02 nM
HDAC7, IC50: 4.46 μM
HDAC8, IC50: 0.954 μM
HDAC9, IC50: 6.72 μM
HDAC10, IC50: 7.57 μM
HDAC11, IC50: 5.14 μM
    Pan Inhibitor 97.92%
Abexinostat
HDAC3/SMRT, Ki: 8.2 nM
 
HDAC1, Ki: 7 nM
HDAC2, Ki: 19 nM
   
HDAC6, Ki: 17 nM
 
HDAC8, Ki: 280 nM
 
HDAC10, Ki: 24 nM
      Pan Inhibitor 98.61%
Pracinostat
HDAC3, IC50: 43 nM
 
HDAC1, IC50: 49 nM
HDAC2, IC50: 96 nM
HDAC4, IC50: 56 nM
HDAC5, IC50: 47 nM
HDAC6, IC50: 1008 nM
HDAC7, IC50: 137 nM
HDAC8, IC50: 140 nM
HDAC9, IC50: 70 nM
HDAC10, IC50: 40 nM
HDAC11, IC50: 93 nM
    Pan Inhibitor 99.07%
RG2833
HDAC3, IC50: 50 nM
 
HDAC1, IC50: 60 nM
                      Pan Inhibitor 99.31%
ACY-775
HDAC3, IC50: 11223 nM
 
HDAC1, IC50: 2123 nM
HDAC2, IC50: 2570 nM
   
HDAC6, IC50: 7.5 nM
              Pan Inhibitor 99.54%
CAY10603
HDAC3, IC50: 0.42 nM
 
HDAC1, IC50: 271 nM
HDAC2, IC50: 252 nM
   
HDAC6, IC50: 0.002 nM
 
HDAC8, IC50: 6851 nM
 
HDAC10, IC50: 90.7 nM
      Pan Inhibitor 95.39%
Givinostat hydrochloride monohydrate
hHDAC3, IC50: 157 nM
 
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC4, IC50: 1059 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
Pan Inhibitor >98.0%
CUDC-101
HDAC3, IC50: 9.1 nM
HDAC, IC50: 4.4 nM
HDAC1, IC50: 4.5 nM
HDAC2, IC50: 12.6 nM
HDAC4, IC50: 13.2 nM
HDAC5, IC50: 11.4 nM
HDAC6, IC50: 5.1 nM
HDAC7, IC50: 373 nM
HDAC8, IC50: 79.8 nM
HDAC9, IC50: 67.2 nM
HDAC10, IC50: 26.1 nM
      Pan Inhibitor 99.59%
Citarinostat
HDAC3, IC50: 46 nM
 
HDAC1, IC50: 35 nM
HDAC2, IC50: 45 nM
   
HDAC6, IC50: 2.6 nM
HDAC7, IC50: 7300 nM
HDAC8, IC50: 137 nM
          Pan Inhibitor 99.06%
EDO-S101
HDAC3, IC50: 25 nM
 
HDAC1, IC50: 9 nM
HDAC2, IC50: 9 nM
   
HDAC6, IC50: 6 nM
 
HDAC8, IC50: 107 nM
 
HDAC10, IC50: 72 nM
      Pan Inhibitor 98.09%
Domatinostat tosylate
HDAC-3, IC50: 0.57 μM
 
HDAC-1, IC50: 1.2 μM
HDAC-2, IC50: 1.12 μM
 
HDAC-5, IC50: 11.3 μM
     
HDAC-9, IC50: 50 μM
HDAC-10, IC50: 21 μM
HDAC-11, IC50: 9.7 μM
    Pan Inhibitor 98.81%
ACY-957
HDAC3, IC50: 1300 nM
 
HDAC1, IC50: 7 nM
HDAC2, IC50: 18 nM
                    Pan Inhibitor 99.91%
HPOB
HDAC3/NCOR2, IC50: 1.7 μM
 
HDAC1, IC50: 2.9 μM
HDAC2, IC50: 4.4 μM
   
HDAC6, IC50: 0.056 μM
 
HDAC8, IC50: 2.8 μM
 
HDAC10, IC50: 3.0 μM
      Pan Inhibitor >95.0%
Domatinostat
HDAC-3, IC50: 0.57 μM
 
HDAC-1, IC50: 1.2 μM
HDAC-2, IC50: 1.12 μM
 
HDAC-5, IC50: 11.3 μM
     
HDAC-9, IC50: 50 μM
HDAC-10, IC50: 21 μM
HDAC-11, IC50: 9.7 μM
    Pan Inhibitor 98.99%
BG45
HDAC3, IC50: 0.289 μM
 
HDAC1, IC50: 2.0 μM
HDAC2, IC50: 2.2 μM
                    Pan Inhibitor 99.71 %
Bufexamac
HDAC3, Kd app: 341 μM
         
HDAC6, Kd app: 10.7 μM
 
HDAC8, Kd app: 235 μM
 
HDAC10, Kd app: 12.3 μM
      Pan Inhibitor >98.0%
Droxinostat
HDAC3, IC50: 16.9 μM
         
HDAC6, IC50: 2.47 μM
 
HDAC8, IC50: 1.46 μM
          Pan Inhibitor 98.86%
CXD101
HDAC3, IC50: 550 nM
 
HDAC1, IC50: 63 nM
HDAC2, IC50: 570 nM
                    Pan Inhibitor 99.14%
Givinostat
hHDAC3, IC50: 157 nM
 
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC4, IC50: 1059 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
Pan Inhibitor
Pimelic Diphenylamide 106
HDAC3, IC50: 370 nM
 
HDAC1, IC50: 150 nM
HDAC2, IC50: 760 nM
       
HDAC8, IC50: 5000 nM
          Pan Inhibitor >98.0%
Resminostat
HDAC3, IC50: 50.1 nM
 
HDAC1, IC50: 42.5 nM
     
HDAC6, IC50: 71.8 nM
 
HDAC8, IC50: 877 nM
          Pan Inhibitor
UF010
HDAC3, IC50: 0.06 μM
 
HDAC1, IC50: 0.5 μM
HDAC2, IC50: 0.1 μM
   
HDAC6, IC50: 9.1 μM
 
HDAC8, IC50: 1.5 μM
 
HDAC10, IC50: 15.3 μM
HDAC11, IC50: 44.5 μM
    Pan Inhibitor 99.36%
AES-135
HDAC3, IC50: 654 nM
         
HDAC6, IC50: 190 nM
       
HDAC11, IC50: 636 nM
    Pan Inhibitor
CHDI-390576
HDAC3, IC50: 25.8 μM
 
HDAC1, IC50: 39.7 μM
 
HDAC4, IC50: 54 nM
HDAC5, IC50: 60 nM
hHDAC6, IC50: 6.2 μM
HDAC7, IC50: 31 nM
HDAC8, IC50: 9.1 μM
hHDAC9, IC50: 50 nM
        Pan Inhibitor
Givinostat hydrochloride
hHDAC3, IC50: 157 nM
 
hHDAC1, IC50: 198 nM
hHDAC2, IC50: 325 nM
hHDAC4, IC50: 1059 nM
hHDAC5, IC50: 532 nM
hHDAC6, IC50: 315 nM
hHDAC7, IC50: 524 nM
hHDAC8, IC50: 854 nM
hHDAC9, IC50: 541 nM
hHDAC10, IC50: 340 nM
hHDAC11, IC50: 292 nM
HD1-B, IC50: 7.5 nM
HD1-A, IC50: 16 nM
HD2, IC50: 10 nM
Pan Inhibitor
CRA-026440
HDAC3, Ki: 11 nM
 
HDAC1, Ki: 4 nM
HDAC2, Ki: 14 nM
   
HDAC6, Ki: 15 nM
 
HDAC8, Ki: 7 nM
 
HDAC10, Ki: 20 nM
      Pan Inhibitor