1. Signaling Pathways
  2. JAK/STAT Signaling
    Stem Cell/Wnt
  3. STAT
  4. STAT3 Inhibitors

STAT3 Inhibitors

STAT3

STAT5

STAT6

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Sorry. There is currently no product that acts on isoform STAT3 together.

Please try each isoform separately.

STAT3 Specific Inhibitors & Activators
Product Name STAT3 STAT5 STAT3 Selectivity Purity
Stattic
STAT3
  Selective Inhibitor >98.0%
NSC 74859
STAT3, IC50: 86 μM
  Selective Inhibitor 99.50%
C188-9
STAT3, Kd: 4.7 nM
  Selective Inhibitor 99.50%
UC-514321
STAT3
STAT5
Selective Inhibitor >98.0%
Niclosamide
STAT3, IC50: 0.25 μM (in HeLa cells)
  Selective Inhibitor 98.68%
Artesunate
Stat-3
  Selective Inhibitor >98.0%
Homoharringtonine
STAT3
  Selective Inhibitor 99.96%
WP1066
STAT3
  Selective Inhibitor 99.90%
Colivelin TFA
STAT3
  Selective Activator 95.29%
Scutellarin
STAT3
  Selective Inhibitor >98.0%
BP-1-102
STAT3, IC50: 6.8 μM
  Selective Inhibitor 99.36%
Nifuroxazide
STAT3
  Selective Inhibitor 99.20%
Cucurbitacin I
STAT3
  Selective Inhibitor >98.0%
Alantolactone
STAT3
  Selective Inhibitor 99.94%
Saikosaponin D
STAT3
  Selective Inhibitor >98.0%
HJC0152 hydrochloride
STAT3
  Selective Inhibitor 98.86%
Diosgenin
STAT3
  Selective Inhibitor >98.0%
HO-3867
STAT3
  Selective Inhibitor 99.68%
Dihydroisotanshinone I
STAT3
  Selective Inhibitor 99.52%
Morusin
STAT3
  Selective Inhibitor 99.83%
Balsalazide
STAT3
  Selective Inhibitor 99.20%
SH5-07
STAT3, IC50: 3.9 μM
  Selective Inhibitor >98.0%
inS3-54A18
STAT3
  Selective Inhibitor 99.83%
Mogrol
STAT3
  Selective Inhibitor 98.06%
SD-36
STAT3, Kd: 50 nM
  Selective Inhibitor
Golotimod hydrochloride
STAT3
  Selective Inhibitor 98.90%
Corylifol A
STAT3, IC50: 0.81 μM
  Selective Inhibitor 99.75%
Isocryptotanshinone
STAT3
  Selective Inhibitor >98.0%
SI-109
STAT3, Ki: 9 nM
  Selective Inhibitor
Ochromycinone
STAT3
  Selective Inhibitor
Colivelin
STAT3
  Selective Activator
Golotimod TFA
STAT3
  Selective Inhibitor
Tetramethylcurcumin
STAT3
  Selective Inhibitor
Golotimod
STAT3
  Selective Inhibitor
APTSTAT3-9R
STAT3
  Selective Inhibitor
HJC0416 hydrochloride
STAT3
  Selective Inhibitor
Balsalazide sodium hydrate
STAT3
  Selective Inhibitor
ENMD-119
STAT3
  Selective Inhibitor
Niclosamide monohydrate
STAT3, IC50: 0.25 μM (in HeLa cells)
  Selective Inhibitor
Reticuline
STAT3
  Pan Inhibitor 98.11%
Triacetylresveratrol
STAT3
  Pan Inhibitor >98.0%
Pimozide
STAT3
STAT5
Pan Inhibitor 99.88%
SH-4-54
STAT3, Kd: 300 nM
STAT5, Kd: 464 nM
Pan Inhibitor 99.59%
Garcinone D
p-STAT3
  Pan Activator 98.18%
Arnicolide D
STAT3
  Pan Inhibitor >99.0%
Protosappanin A
STAT3
  Pan 98.88%
STAT3-IN-1
Stat-3, IC50: 1.82 μM (in HT29 cells)
Stat-3, IC50: 2.14 μM (in MDA-MB 231 cells)
  Pan Inhibitor 96.54%
Pimozide D4
STAT3
STAT5
Pan Inhibitor
Garcinone C
Stat-3
  Pan Inhibitor
Eupalinolide K
STAT3
  Pan Inhibitor
TPCA-1
STAT3
  default Inhibitor 99.58%
STAT3-IN-3
STAT3
  default Inhibitor 98.08%
Ascochlorin
STAT3
  default Inhibitor