ILT-7/CD85g
ILT-7, also designated CD85g or LILRA4, is a human LILR family receptor whose expression is highly selective for plasmacytoid dendritic cells, with additional reports in basophils. The molecule carries Ig-like extracellular domains and a short cytoplasmic tail, and cross-linking has been reported to inhibit TLR9-driven production of type I interferon in plasmacytoid dendritic cells. Because pDCs generate abundant IFN-alpha in autoimmune conditions such as psoriasis and lupus, ILT-7 is studied as a pDC-specific regulatory receptor. Its selective expression also makes ILT-7 a standard flow cytometric marker for identifying and isolating plasmacytoid dendritic cells.
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ILT-7/CD85g Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
