DC-SIGN1/CD209
DC-SIGN1, assigned CD209, is a C-type lectin receptor built from a carbohydrate-recognition domain, a neck region with tandem repeats, and a transmembrane anchor. It recognizes high-mannose and fucosylated glycans such as those on ICAM-3 and ICAM-2, mediating both antigen capture by dendritic cells and trans-endothelial migration. DC-SIGN1 is prominent on immature monocyte-derived dendritic cells and on macrophages of placenta and lung. It is well known as an attachment factor for enveloped viruses, with HIV-1, SARS-CoV, and dengue virus among those that use the lectin to enhance infection or dissemination. Recombinant DC-SIGN1/CD209 is employed in glycan-binding studies, viral attachment assays, and adjuvant research.
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DC-SIGN1/CD209 Recombinant Proteins (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
