2. Click Chemistry
  3. TCO

TCO

TCO (101):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-148057
    TCO-PEG4-VC-PAB-MMAE 2758671-45-1 99.30%
    TCO-PEG4-VC-PAB-MMAE is a agent-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162). TCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    TCO-PEG4-VC-PAB-MMAE
  • HY-136050
    TCO-PEG3-Biotin 2098630-62-5 99.41%
    TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    TCO-PEG3-Biotin
  • HY-141186
    TCO-OH 85081-69-2 99.91%
    TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
    TCO-OH
  • HY-151696
    TCO-PEG3-maleimide 1809356-72-6 99.9%
    TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides).
    TCO-PEG3-maleimide
  • HY-141169
    TCO-PEG8-NHS ester 2353409-95-5
    TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    TCO-PEG8-NHS ester
  • HY-141178
    TCO-PEG3-amine 1800507-93-0
    TCO-PEG3-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    TCO-PEG3-amine
  • HY-141177
    TCO-PEG2-amine 2141981-87-3
    TCO-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    TCO-PEG2-amine
  • HY-141170
    TCO-PEG12-NHS ester 2185016-39-9
    TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
    TCO-PEG12-NHS ester
  • HY-140731
    TCO-PEG5000-TCO
    TCO-PEG5000-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. TCO-PEG5000-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    TCO-PEG5000-TCO
  • HY-141175
    TCO-PNB ester 1438415-89-4 98.52%
    TCO-PNB ester is an amine-reactive building block used for modification of amine-containing molecule. TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
    TCO-PNB ester
  • HY-151698
    TCO-NHS Ester (axial) 1610931-22-0 99.84%
    TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    TCO-NHS Ester (axial)
  • HY-141190
    Gly-Gly-Gly-PEG3-TCO 2353409-81-9 99.90%
    Gly-Gly-Gly-PEG3-TCO is a 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Gly-Gly-Gly-PEG3-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    Gly-Gly-Gly-PEG3-TCO
  • HY-141184
    TCO-PEG9-maleimide 2183440-37-9 98.6%
    TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
    TCO-PEG9-maleimide
  • HY-D2143
    Cy5-PEG3-TCO 99.23%
    Cy5-PEG3-TCO is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
    Cy5-PEG3-TCO
  • HY-133475
    TCO-PEG5-maleimide 99.46%
    TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    TCO-PEG5-maleimide
  • HY-156488
    TCO-PEG7-Maleimide 98.03%
    TCO-PEG7-Maleimide contains TCO groups, and can undergo specific "click" reactions with tetrazine groups.
    TCO-PEG7-Maleimide
  • HY-156392
    TCO4-PEG7-Maleimide 98.95%
    TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
    TCO4-PEG7-Maleimide
  • HY-133428
    DBCO-PEG3-TCO 2755573-20-5 98.0%
    DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG3-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG3-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    DBCO-PEG3-TCO
  • HY-141180
    TCO-PEG6-amine 2353409-94-4 98.96%
    TCO-PEG6-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    TCO-PEG6-amine
  • HY-151698B
    (R,E)-TCO-NHS Ester 2829292-74-0
    (R,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
    (R,E)-TCO-NHS Ester