1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. TCO-PEG4-NHS ester

TCO-PEG4-NHS ester 

Cat. No.: HY-141167 Purity: 99.58%
Handling Instructions

TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

TCO-PEG4-NHS ester Chemical Structure

TCO-PEG4-NHS ester Chemical Structure

CAS No. : 1613439-69-2

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Description

TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Cleavable

 

Molecular Weight

514.57

Formula

C₂₄H₃₈N₂O₁₀

CAS No.

1613439-69-2

SMILES

O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (97.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9434 mL 9.7169 mL 19.4337 mL
5 mM 0.3887 mL 1.9434 mL 3.8867 mL
10 mM 0.1943 mL 0.9717 mL 1.9434 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

TCO-PEG4-NHS esterADC LinkerAntibody-drug conjugates linkercleavableADCantibody-drugconjugatesInhibitorinhibitorinhibit

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TCO-PEG4-NHS ester
Cat. No.:
HY-141167
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