1. Signaling Pathways
  2. Anti-infection
  3. CMV

CMV

Cytomegalovirus (CMV) is a viral genus of the viral family known as Herpesviridae or herpesviruses. Within Herpesviridae, CMV belongs to the Betaherpesvirinae subfamily, which also includes the genera Muromegalovirus and Roseolovirus (HHV-6 and HHV-7). All herpesviruses share a characteristic ability to remain latent within the body over long periods. Although they may be found throughout the body, CMV infections are frequently associated with the salivary glands in humans and other mammals. Several species of Cytomegalovirus have been identified and classified for different mammals. Such as Human cytomegalovirus (HCMV), Chimpanzee cytomegalovirus (CCMV), Simian cytomegalovirus (SCCMV) and Rhesus cytomegalovirus(RhCMV) etc..

CMV Related Products (21):

Cat. No. Product Name Effect Purity
  • HY-B0097
    Floxuridine Inhibitor 99.93%
    Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis. Floxuridine has antiviral effects against HSV and CMV.
  • HY-16305
    Maribavir Inhibitor 98.69%
    Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus (EBV).
  • HY-17438
    Cidofovir Inhibitor 99.59%
    Cidofovir is an anti-CMV drug which can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription.
  • HY-15233
    Letermovir Inhibitor 99.38%
    Letermovir is a novel inhibitor of CMV, which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors.
  • HY-N1067
    Xanthohumol Inhibitor 99.60%
    Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
  • HY-123523
    Enocitabine Inhibitor >98.0%
    Enocitabine is a nucleoside analog, and is a potent DNA replication inhibitor, and a DNA chain terminator. Enocitabine inhibits the replication of human cytomegalovirus. Enocitabine has antileukemic and antiviral activities.
  • HY-18944
    FIT-039 Inhibitor >98.0%
    FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
  • HY-136199
    SIRT1-IN-1 Inhibitor
    SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity.
  • HY-13578
    Brivudine Inhibitor 99.78%
    Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.
  • HY-14532
    Brincidofovir Inhibitor >98.0%
    Brincidofovir (CMX001; HDP-CDV) is an orally active, lipophilic form of cidofovir (CDV); has enhanced activity in vitro and in vivo compared to CDV against certain herpesviruses, adenoviruses and orthopoxviruses.
  • HY-A0032A
    Valganciclovir hydrochloride Inhibitor >98.0%
    Valganciclovir (hydrochloride), the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir.
  • HY-108261
    Tomeglovir Inhibitor 98.51%
    Tomeglovir is a potent anti-CMV agent, inhibiting processing of viral DNA-concatemers, with IC50s of 0.34 μM and 0.039 μM for HCMV and MCMV.
  • HY-100272
    B220 Inhibitor >99.0%
    B220 is an antiviral agent which can inhibit the growth of HSV-1, HSV-2 and human cytomegalovirus (CMV).
  • HY-16721
    Cyclopropavir Inhibitor
    Cyclopropavir (Filociclovir; ZSM-I-62; MBX-400) is a broad-spectrum anti-herpesvirus compound, has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 with EC50s of 0.7 μM to 8 μM.
  • HY-N0093
    Ancitabine hydrochloride Inhibitor 98.59%
    Ancitabine (hydrochloride) is an important antileukemia drugs.
  • HY-N1127
    Tricin Inhibitor 98.90%
    Tricin is a natural flavonoid present in large amounts in rice bran. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7.
  • HY-P1780
    CEF20
    CEF20 is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).
  • HY-108254
    Bisindolylmaleimide IV Inhibitor
    Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM). Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM.
  • HY-15523
    Braco-19 Inhibitor
    Braco-19 is a potent telomerase/telomere inhibitor and a HAdV virus replication inhibitor. BRACO-19 is a selective and high affinity G-quadruplex (GQ) binding ligand, stabilizing quadruplex formation at the 3V telomeric DNA overhang.
  • HY-A0032
    Valganciclovir Inhibitor
    Valganciclovir, the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections.
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