Cathepsin H
Cathepsin H (CTSH) stands out within the papain-like cathepsin family as the only mammalian member with aminopeptidase rather than endopeptidase activity. This behavior results from a residual octapeptide, termed the mini-chain, that remains bound in the active site after proteolytic processing and directs substrates to be cleaved from the N-terminus. The enzyme is synthesized as a preproenzyme and resides in lysosomes of many tissues, with particularly abundant expression in lung, kidney, and placenta. CTSH has been linked to cancer biology, with elevated levels described in some gastric and colorectal tumors, and it has also been studied in the context of antigen processing.
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Cathepsin H Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
