HBV

HBV Related Products (60):

By Effects:	Inhibitors (58) Activators (1)

Cat. No.	Product Name	Effect	Purity

HY-15142

Doxorubicin hydrochloride	Activator	99.47%
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride inhibits topoisomerase II with an IC₅₀ of 2.67 μM, thus stopping DNA replication. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy. Doxorubicin hydrochloride inhibits human DNA topoisomerase I with an IC₅₀ of 0.8 μM.

HY-107454

OSS_128167	Inhibitor	98.06%
OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC₅₀s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-acncer, anti-inflammation and anti-viral effects.

HY-117650A

RG7834	Inhibitor	99.29%
RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC₅₀s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.

HY-15601

Vesatolimod Inhibitor 99.56%

Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC₅₀ of 291 nM.

Vesatolimod	Inhibitor	99.56%
Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC₅₀ of 291 nM.

HY-13623A

Entecavir monohydrate	Inhibitor	99.95%
Entecavir monohydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC₅₀ of 3.75 nM in HepG2 cell.

HY-19314A

Azvudine hydrochloride	Inhibitor
Azvudine (RO-0622) hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC₅₀s ranging from 0.03 to 6.92 nM) and HIV-2 (EC₅₀s ranging from 0.018 to 0.025 nM). Azvudine hydrochloride inhibits NRTI-resistant viral strains.

HY-W018791

Bifendate Inhibitor 99.91%

Bifendate (DDB) is a synthetic intermediate of Schisandrin C with anti-HBV efficacy in research of chronic hepatitis B.

Bifendate	Inhibitor	99.91%
Bifendate (DDB) is a synthetic intermediate of Schisandrin C with anti-HBV efficacy in research of chronic hepatitis B.

HY-124600

NVR 3-778	Inhibitor	>98.0%
NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM (capsid assembly modulator) belonging to the SBA (sulfamoylbenzamide) class, with anti-HBV activity.

HY-13782

Tenofovir Disoproxil Fumarate Inhibitor 99.80%

Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.
HY-13986

Merimepodib Inhibitor 99.64%

Merimepodib (VX-497) is a noncompetitive and oral inhibitor of inosine monophosphate dehydrogenase (IMPDH) with broad spectrum antiviral activities.
HY-N0058

4,5-Dicaffeoylquinic acid Inhibitor 99.98%

4,5-Dicaffeoylquinic acid ( Isochlorogenic acid C) possesses potent hepatoprotective and anti-HBV effects.
HY-13910

Tenofovir Inhibitor 99.81%

Tenofovir (GS 1278) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV).
HY-100029

Bay 41-4109 Inhibitor 98.39%

BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC₅₀ of 53 nM.
HY-108917

Morphothiadin Inhibitor 99.59%

Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV with an IC₅₀ of 12 nM.
HY-B0255

Adefovir dipivoxil Inhibitor 99.87%

Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.
HY-N0056

Isochlorogenic acid A Inhibitor 99.53%

Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with antioxidant and anti-inflammatory activities .
HY-112142

AB-423 Inhibitor 99.60%

AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC₅₀/EC₉₀ of 0.08-0.27 μM/0.33-1.32 μM in cells.
HY-16468

Squalamine Inhibitor >98.0%

Squalamine(MSI-1256) is an aminosterol compound with potent broad spectrum antiviral activity.

Tenofovir Disoproxil Fumarate	Inhibitor	99.80%
Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.

Merimepodib	Inhibitor	99.64%
Merimepodib (VX-497) is a noncompetitive and oral inhibitor of inosine monophosphate dehydrogenase (IMPDH) with broad spectrum antiviral activities.

4,5-Dicaffeoylquinic acid	Inhibitor	99.98%
4,5-Dicaffeoylquinic acid ( Isochlorogenic acid C) possesses potent hepatoprotective and anti-HBV effects.

Tenofovir	Inhibitor	99.81%
Tenofovir (GS 1278) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV).

Bay 41-4109	Inhibitor	98.39%
BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC₅₀ of 53 nM.

Morphothiadin	Inhibitor	99.59%
Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV with an IC₅₀ of 12 nM.

Adefovir dipivoxil	Inhibitor	99.87%
Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.

Isochlorogenic acid A	Inhibitor	99.53%
Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with antioxidant and anti-inflammatory activities .

AB-423	Inhibitor	99.60%
AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC₅₀/EC₉₀ of 0.08-0.27 μM/0.33-1.32 μM in cells.

Squalamine	Inhibitor	>98.0%
Squalamine(MSI-1256) is an aminosterol compound with potent broad spectrum antiviral activity.

HY-N0054

Osthole	Inhibitor	99.90%
Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H₁ receptor activity. Osthole also suppresses the secretion of HBV in cells.

HY-112564

JNJ-632 Inhibitor 99.36%

JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM).

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