HBV

HBV Related Products (60):

By Effects:	Inhibitors (58) Activators (1)

Cat. No.	Product Name	Effect	Purity

HY-15142

Doxorubicin hydrochloride	Activator	99.47%
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride inhibits topoisomerase II with an IC₅₀ of 2.67 μM, thus stopping DNA replication. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy. Doxorubicin hydrochloride inhibits human DNA topoisomerase I with an IC₅₀ of 0.8 μM.

HY-107454

OSS_128167	Inhibitor	98.06%
OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC₅₀s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-acncer, anti-inflammation and anti-viral effects.

HY-117650A

RG7834	Inhibitor	99.29%
RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC₅₀s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.

HY-15601

Vesatolimod Inhibitor 99.90%

Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC₅₀ of 291 nM.

Vesatolimod	Inhibitor	99.90%
Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC₅₀ of 291 nM.

HY-13623A

Entecavir monohydrate	Inhibitor	99.95%
Entecavir monohydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC₅₀ of 3.75 nM in HepG2 cell.

HY-109197

Vonafexor Inhibitor 99.87%

Vonafexor (EYP001) is a selective FXR agonist with anti-HBV effects.

Vonafexor	Inhibitor	99.87%
Vonafexor (EYP001) is a selective FXR agonist with anti-HBV effects.

HY-19314A

Azvudine hydrochloride	Inhibitor
Azvudine (RO-0622) hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC₅₀s ranging from 0.03 to 6.92 nM) and HIV-2 (EC₅₀s ranging from 0.018 to 0.025 nM). Azvudine hydrochloride inhibits NRTI-resistant viral strains.

HY-B1464

Cetylpyridinium chloride	Inhibitor	>98.0%
Cetylpyridinium chloride, a cationic quaternary ammonium compound, is an anti-bacterial agent with broad-spectrum activity. Cetylpyridinium chloride is an effective anti-HBV capsid assembly inhibitor with an IC₅₀ of 2.5 μM. Cetylpyridinium chloride is used in pesticides and various types of mouthwashes, and other personal care products.

HY-13986

Merimepodib Inhibitor 98.91%

Merimepodib (VX-497) is a noncompetitive and oral inhibitor of inosine monophosphate dehydrogenase (IMPDH) with broad spectrum antiviral activities.
HY-13782

Tenofovir Disoproxil Fumarate Inhibitor 99.80%

Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.
HY-13910

Tenofovir Inhibitor 99.81%

Tenofovir (GS 1278) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV).
HY-N0058

4,5-Dicaffeoylquinic acid Inhibitor 99.98%

4,5-Dicaffeoylquinic acid ( Isochlorogenic acid C) possesses potent hepatoprotective and anti-HBV effects.
HY-N0056

Isochlorogenic acid A Inhibitor 99.53%

Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with antioxidant and anti-inflammatory activities .

Merimepodib	Inhibitor	98.91%
Merimepodib (VX-497) is a noncompetitive and oral inhibitor of inosine monophosphate dehydrogenase (IMPDH) with broad spectrum antiviral activities.

Tenofovir Disoproxil Fumarate	Inhibitor	99.80%
Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.

Tenofovir	Inhibitor	99.81%
Tenofovir (GS 1278) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV).

4,5-Dicaffeoylquinic acid	Inhibitor	99.98%
4,5-Dicaffeoylquinic acid ( Isochlorogenic acid C) possesses potent hepatoprotective and anti-HBV effects.

Isochlorogenic acid A	Inhibitor	99.53%
Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with antioxidant and anti-inflammatory activities .

HY-B0255

Adefovir dipivoxil	Inhibitor	99.87%
Adefovir dipivoxil, an adenosine analogue, is an oral prodrug of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains.

HY-100029

Bay 41-4109 Inhibitor 98.39%

BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC₅₀ of 53 nM.
HY-108917

Morphothiadin Inhibitor 99.59%

Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV with an IC₅₀ of 12 nM.

Bay 41-4109	Inhibitor	98.39%
BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC₅₀ of 53 nM.

Morphothiadin	Inhibitor	99.59%
Morphothiadin is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV with an IC₅₀ of 12 nM.

HY-N0054

Osthole	Inhibitor	99.95%
Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H₁ receptor activity. Osthole also suppresses the secretion of HBV in cells.

HY-N0664

Aucubin	Inhibitor	>98.0%
Aucubin is an iridoid glycoside with a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.

HY-16468

Squalamine Inhibitor >98.0%

Squalamine(MSI-1256) is an aminosterol compound with potent broad spectrum antiviral activity.
HY-112564

JNJ-632 Inhibitor 99.36%

JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM).

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