1. Screening Libraries
  2. Fragment Libraries

Fragment Libraries

Fragment-based drug discovery (FBDD) is a powerful method to develop potent small-molecule compounds starting from fragments binding weakly to targets. FBDD starts by screening libraries of low-molecular weight compounds (fragments) against the target of interest to identify ‘‘hits.’’ The identified hit is then grown into drug-like molecules through different strategies. Although FBDD cannot replace high-throughput screening (HTS) campaigns in drug discovery, it has some attractive advantages such as saving experimental cost, offering diverse hits, and exhibiting multiple ways to develop novel compounds.

Cat. No.
  • HY-L154 Cysteine Targeted Covalent Fragment Library Compound library containing fragments with various warheads targeting cysteine residue. 2917 compounds
    HY-L152 F-Fragments Library Unique F (fluorine)-containing compounds developed for fragment-based drug discovery. 4868 compounds
    HY-L032 Fragment Library Unique compounds developed for fragment-based drug discovery. 22029 compounds
    HY-L903 3D Diverse Fragment Library Unique 3D diversity fragment library: a new opportunity for fragment-based drug discovery (FBDD). 5196 compounds