1. Signaling Pathways
  2. Apoptosis
  3. FKBP



FKBP Related Products (10):

Cat. No. Product Name Effect Purity
  • HY-10219
    Rapamycin 99.93%
    Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator.
  • HY-10218
    Everolimus 98.79%
    Everolimus (RAD001) is a potent mTOR inhibitor that binds to FKBP-12 to generate an immunosuppressive complex.
  • HY-13756
    Tacrolimus 98.46%
    Tacrolimus is a macrocyclic lactone with potent immunosuppressive properties. Tacrolimus binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase.
  • HY-16046
    Rimiducid Activator 99.39%
    Rimiducid (AP1903) is a dimerizer agent that acts by cross-linking the FKBP domains, initiating Fas signaling and hence apoptosis.
  • HY-13992
    AP20187 Modulator 99.80%
    AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions.
  • HY-102079
    SAFit1 Inhibitor
    SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.3 nM.
  • HY-114434
    AP1867 is a synthetic FKBP12F36V-directed ligand.
  • HY-13756A
    Tacrolimus monohydrate 98.46%
    Tacrolimus monohydrate binds to FK506 binding protein (FKBP). This complex inhibits calcineurin phosphatase (PP2B). Tacrolimus monohydrate is a mTOR-independent autophagy inducer.
  • HY-102080
    SAFit2 Antagonist 98.59%
    SAFit2 is a novel, selective FK506-binding protein 51 (FKBP51) antagonist with a Ki of 6 nM and also enhances AKT2-AS160 binding.
  • HY-107452
    PROTAC FKBP12-binding moiety 1
    PROTAC FKBP12-binding moiety 1 is a synthetic ligand for FKBP (SLF), which is used in the synthesis of PROTACs.
Isoform Specific Products

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.