Stimulatory Immune Checkpoint Molecules
As opposed to inhibitory pathways that attenuate the immune system, co-stimulatory molecules augment immunological responses against malignant cells. Malignant cells often inhibit co-stimulatory pathways to promote tumor genesis. As stimulatory checkpoint molecules, such as OX40, GITR, ICOS, 4-1BB and CD40, play key roles in regulating the effector functions of T cells, activating co-stimulatory pathways may improve checkpoint inhibition efficacy, and lead to durable antitumor responses.
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Stimulatory Immune Checkpoint Molecules Recombinant Proteins (316)
CD40L/CD154/TRAP Protein, Human (His)
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Cat. No.: HY-P72907
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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CD40L/CD154/TRAP Trimer Protein, Human (HEK293, His-Flag)
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Cat. No.: HY-P78425
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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B7-1/CD80 Protein, Human (HEK293, His)
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Cat. No.: HY-P70651
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD80; B-Lymphocyte Activation Antigen B7; Prev. CD28LG1; LAB7; Prev. CD28LG; BB1; T-Lymphocyte Activation Antigen CD80; B7; Activation B7-1 Antigen; Costimulatory Molecule Variant IgV-CD80; B7.1; Costimulatory Factor CD80; B7-1; CD80 Molecule; CD80 Antige
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CD40L/CD154/TRAP Protein, Mouse (HEK293, His)
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Cat. No.: HY-P70808
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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CD40L/CD154/TRAP Protein, Human (HEK293, hFc-Flag)
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Cat. No.: HY-P72028
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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CD40 Protein, Human (HEK293, His)
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Cat. No.: HY-P73499A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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PVR/CD155 Protein, Human (HEK293)
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Cat. No.: HY-P75614
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PVR; Tage4; Prev. PVS; Nectin-Like Protein 5; Poliovirus Receptor; Poliovirus Receptor, Isoform CRA_c; Necl-5; Nectin-Like 5; CD155; CD155 Antigen; NECL5; NECL-5; PVR Cell Adhesion Molecule; HVED
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CD40L/CD154/TRAP Trimer Protein, Mouse (HEK293, Fc)
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Cat. No.: HY-P78271
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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B7-1/CD80 Protein, Human (HEK293, Fc)
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Cat. No.: HY-P7321
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD80; B-Lymphocyte Activation Antigen B7; Prev. CD28LG1; LAB7; Prev. CD28LG; BB1; T-Lymphocyte Activation Antigen CD80; B7; Activation B7-1 Antigen; Costimulatory Molecule Variant IgV-CD80; B7.1; Costimulatory Factor CD80; B7-1; CD80 Molecule; CD80 Antige
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4-1BBL/TNFSF9 Trimer Protein, Human (Biotinylated, HEK293, Fc, Flag)
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Cat. No.: HY-P78069
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF9; Homolog Of Mouse 4-1BB-L; TNF Superfamily Member 9; Receptor 4-1BB Ligand; 4-1BBL; CD137 Ligand; 4-1BB-L; 4-1BB Ligand; CD137L; Tumor Necrosis Factor (Ligand) Superfamily, Member 9, Isoform CRA_a; Tumor Necrosis Factor (Ligand) Superfamily, Member
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CD40 Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P78091
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
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OX40 Ligand/TNFSF4 Trimer Protein, Human (HEK293, His-Flag)
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Cat. No.: HY-P78504
Purity: ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF4; Tumor Necrosis Factor (Ligand) Superfamily Member 4; Prev. TXGP1; Tumor Necrosis Factor Superfamily Member 4; Tumor Necrosis Factor Ligand Superfamily Member 4; Tumor Necrosis Factor Ligand 2B; OX-40L; OX40 Antigen Ligand; CD252; CD252 Antigen; Gp
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CD28 Protein, Human/Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, Fc-Avi)
PVR/CD155 Protein, Human (HEK293, His)
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Cat. No.: HY-P70807
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PVR; Tage4; Prev. PVS; Nectin-Like Protein 5; Poliovirus Receptor; Poliovirus Receptor, Isoform CRA_c; Necl-5; Nectin-Like 5; CD155; CD155 Antigen; NECL5; NECL-5; PVR Cell Adhesion Molecule; HVED
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Nectin-2/CD112 Protein, Human (HEK293)
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Cat. No.: HY-P73307
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NECTIN2; Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B); Prev. PVRL2; Herpes Virus Entry Mediator B; Prev. HVEB; Herpesvirus Entry Mediator B; Nectin-2; Herpesvirus Entry Protein B; PRR2; Poliovirus Receptor-Like 2; PVRR2; CD112 Antigen; CD1
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Nectin-2/CD112 Protein, Human (HEK293, His)
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Cat. No.: HY-P7780
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NECTIN2; Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B); Prev. PVRL2; Herpes Virus Entry Mediator B; Prev. HVEB; Herpesvirus Entry Mediator B; Nectin-2; Herpesvirus Entry Protein B; PRR2; Poliovirus Receptor-Like 2; PVRR2; CD112 Antigen; CD1
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PVR/CD155 Protein, Human (Biotinylated, HEK293, His-Avi)
OX40/TNFRSF4 Protein, Human (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P78189
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis Factor Receptor Superfamily, Member 4; Tumor Necrosis Factor Receptor Superfamily Member 4; Lymphoid Activation Antigene ACT35; OX40L Receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
