Diversity Compound Libraries
It is proved that a diverse compound library is the most successful and straightforward starting point to find new leads. Moreover, it is the best way to enhance the research compound collections by adding new substances with different chemotypes. MCE can provide 50K Diversity Library (50,000 compounds) and 5K Scaffold Library (5,000 compounds) which are an ideal starting library for phenotypic and target-based HTS. Compounds in these libraries were selected by dissimilarity search to provide a higher variety and broader chemical space coverage. All the compounds are drug-like and have been screened to remove any inappropriate chemical structures, avoiding “false hits”.
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5K Scaffold Library4,999 compoundsHY-L902
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50K Diversity Library50,000 compoundsHY-L901
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Natural Product-like Compound Library4,813 compoundsHY-L905
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Lead-like Diversity Library Plus80,000 compoundsHY-L901P
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MCE‑18 Novelty Focused Drug‑Like Library11028 compoundsHY-L944
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Allosteric Modulator Lead‑like Compound Library4,236 compoundsHY-L941
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10K Golden Scaffold Library9,957 compoundsHY-L927
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MCE‑18 Novelty drug‑like Library37030 compoundsHY-L943
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Good ADMET Diversity Library25000 compoundsHY-L922
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Norepinephrine Transporter (NET) Compound Library646 compoundsHY-L906
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Antibacterial Lead-like compound library10855 compoundsHY-L939
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Molecular Glue-like Compound Library317 compoundsHY-L918
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GPCR Targeted Diversity Library7,106 compoundsHY-L928
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Cysteine Protease Focused Library9,363 compoundsHY-L925
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Antiviral Lead-like compound library5,818 compoundsHY-L940
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PD-1/PD-L1 Lead-like Library11,491 compoundsHY-L948
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MCE CNS BBB Lead-like Library27,503 compoundsHY-L919
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CNS MPO Lead-like Library24,816 compoundsHY-L920
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Ion Channel Lead-like Compound Library9000 compoundsHY-L923
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Cysteine Protease Focused Covalent Library2,109 compoundsHY-L926
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Antifungal Lead-like compound library8350 compoundsHY-L938
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RNA Binding Library5,619 compoundsHY-L917