CD319/SLAMF7
CD319, also known as SLAMF7, CS1 or CRACC, is a member of the signaling lymphocytic activation molecule family with an extracellular IgV-like domain that mediates homophilic interaction. The receptor is expressed on natural killer cells, activated B cells, plasma cells and subsets of T cells and myeloid cells. In NK cells its cytoplasmic tail recruits the EAT-2 adapter to support cytotoxic responsiveness, while in plasma cells it functions as a surface anchor rather than a signaling molecule. SLAMF7 is displayed at high density on malignant plasma cells in multiple myeloma, and the antibody elotuzumab directed against it was approved for myeloma therapy.
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CD319/SLAMF7 Recombinant Proteins (11)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
