Fc-epsilon Receptor
Fc epsilon receptor (FcεR) is the Fc receptor that binding immunoglobulin E (IgE). There are two types of FcεRs, called FcεRI (or high-affinity Fc epsilon R, Kd ~1nm) and FcεRII/CD23 (or low-affinity Fc epsilon R, Kd 0.1-1μm). FceRI and FcεRII/CD23 are very different in their molecular structure. FceRI belongs to the immunoglobulin superfamily and is highly homologous in sequence and structure to the IgG Fc receptors, while FcεRII/CD23 is a member of the C-type lectin superfamily. FcεRII/CD23 receptors are expressed on B cells, a variety of innate cell types and epithelial cells. FcεRI receptors are expressed on a variety of cells in addition to mast cells and basophils.A handful of other receptors, including galectin-3, FcγRIIb, FcγRIV, have been documented to interact with IgE.
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Fc-epsilon Receptor Recombinant Proteins (7)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
