Cat. No.: HY-L035

Drug Repurposing Compound Library

103 Cited Publications

Customer Review

Based on 103 publication(s) in Google Scholar

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved and clinical drugs, especially after phase I drugs, have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.

MCE Drug Repurposing Compound Library contains 5,112 approved drugs and passed phase Ⅰclinical drugs, which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Description & Advantages
Product Details
- Formulation
- Layout
- Container
- Storage
- Shipping
Publications (103)
Documentation

Description & Advantages

• A unique collection of 5,112 compounds that have been marketed or successfully passed through Phases I for high throughput screening (HTS) and high content screening (HCS).

• Used in the research of oncology, cardiology, anti-inflammatory, immunology, dermatology, endocrinology, neurology, and more.

• A useful tool for drug repurposing.

• Structurally diverse, bioactive, and cell permeable.

• More detailed compound information with structure, IC₅₀, and brief introduction.

• NMR and HPLC validated ensure high purity.

• All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 5,112 bioactive compounds supplied as pre-dissolved Solutions or Solid

Solution: 4,955 compounds supplied in 10 mM solution, 120 compounds supplied in 2 mM solution, 37 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage

-80°C

Shipping

Blue ice or dry ice