1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin

Microtubule/Tubulin

Microtubule/Tubulin Related Products (65):

Cat. No. Product Name Effect Purity
  • HY-B0015
    Paclitaxel Inhibitor 99.51%
    Paclitaxel is a potent anticancer agent known to promote microtubule (MT) assembly, inhibit MT depolymerization, and change MT dynamics required for mitosis and cell proliferation.
  • HY-13520
    Nocodazole Inhibitor 99.05%
    Nocodazole is a rapidly-reversible inhibitor of microtubule polymerization, which exhibits good potency against ABL, ABL(E255K), and ABL(T315I) with IC50 values of 0.21 μM, 0.53 μM, and 0.64 μM, respectively, and increases CRISPR/Cas9-mediated editing frequencies.
  • HY-15162
    Monomethyl auristatin E Inhibitor 99.92%
    Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin, and also shows inhibition of antibody-drug conjugates (ADCs) activity.
  • HY-B0011
    Docetaxel Inhibitor 99.8%
    Docetaxel is a semi-synthetic taxane analogue, acts as a microtubule stabilizer.
  • HY-15575
    VcMMAE Inhibitor 99.66%
    VcMMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).
  • HY-N2146
    Combretastatin A4 Inhibitor
    Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
  • HY-14672
    Auristatin PE Inhibitor 99.76%
    Auristatin PE is a novel synthetic Dolastatin 10 derivative and inhibitor of tubulin polymerization.
  • HY-10340B
    KX2-391 Mesylate Inhibitor 99.97%
    KX2-391 Mesylate is a synthetic, orally bioavailable inhibitor of Src kinase and tubulin polymerization.
  • HY-N0488
    Vincristine sulfate Inhibitor 99.63%
    Vincristine (sulfate) is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM in a cell-free assay.
  • HY-15459
    Cabazitaxel Inhibitor 99.89%
    Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
  • HY-16569
    Colchicine Inhibitor 99.56%
    Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine triggers apoptosis.
  • HY-12033
    2-Methoxyestradiol Inhibitor 99.54%
    2-Methoxyestradiol is a microtubule and HIF-1 inhibitor, binds to tubulin at or near the colchicine site and inhibits the polymerization of tubulin in vitro, works by interfering with normal microtubule function.
  • HY-15278
    Epothilone D Inhibitor 99.86%
    Epothilone D is a potent microtubule stabilizer.
  • HY-10222
    Ixabepilone Inhibitor
    Ixabepilone is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.
  • HY-17029
    Epothilone B Inhibitor 99.78%
    Epothilone B is a microtubule (MT) targeting agent with EC0.01 of 1.8 μM.
  • HY-12053A
    Vinorelbine ditartrate Inhibitor 99.62%
    Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
  • HY-17418
    Vinblastine Inhibitor 98.38%
    Vinblastine is a cytotoxic alkaloid used against various cancer types. Vinblastine inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM.
  • HY-19792
    Mertansine Inhibitor
    Mertansine is a tubulin inhibitor,inhibits the assemblyof microtubules by binding to tubulin, with a linker structure can create an antibody-drug conjugate (ADC).
  • HY-15739
    Ansamitocin P-3 Inhibitor
    Ansamitocin P-3 is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
  • HY-15162A
    D8-MMAE Inhibitor
    D8-MMAE is a deuterated form of MMAE, which is a microtubule-disrupting agent.