1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin

Microtubule/Tubulin

Microtubule/Tubulin Related Products (65):

Cat. No. Product Name Effect Purity
  • HY-B0015
    Paclitaxel Inhibitor
    Paclitaxel is a potent anticancer agent known to promote microtubule (MT) assembly, inhibit MT depolymerization, and change MT dynamics required for mitosis and cell proliferation.
  • HY-13520
    Nocodazole Inhibitor
    Nocodazole is a rapidly-reversible inhibitor of microtubule polymerization, which exhibits good potency against ABL, ABL(E255K), and ABL(T315I) with IC50 values of 0.21 μM, 0.53 μM, and 0.64 μM, respectively, and increases CRISPR/Cas9-mediated editing frequencies.
  • HY-15162
    Monomethyl auristatin E Inhibitor
    Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin, and also shows inhibition of antibody-drug conjugates (ADCs) activity.
  • HY-B0011
    Docetaxel Inhibitor
    Docetaxel is a semi-synthetic taxane analogue, acts as a microtubule stabilizer.
  • HY-15575
    VcMMAE Inhibitor
    VcMMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).
  • HY-14672
    Auristatin PE Inhibitor
    Auristatin PE is a novel synthetic Dolastatin 10 derivative and inhibitor of tubulin polymerization.
  • HY-15459
    Cabazitaxel Inhibitor
    Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
  • HY-16569
    Colchicine Inhibitor
    Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine triggers apoptosis.
  • HY-12033
    2-Methoxyestradiol Inhibitor
    2-Methoxyestradiol is a microtubule and HIF-1 inhibitor, binds to tubulin at or near the colchicine site and inhibits the polymerization of tubulin in vitro, works by interfering with normal microtubule function.
  • HY-15278
    Epothilone D Inhibitor
    Epothilone D is a potent microtubule stabilizer.
  • HY-10222
    Ixabepilone Inhibitor
    Ixabepilone is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis.
  • HY-17029
    Epothilone B Inhibitor
    Epothilone B is a microtubule (MT) targeting agent with EC0.01 of 1.8 μM.
  • HY-13270
    ABT-751 Inhibitor
    ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.
  • HY-14949
    Cevipabulin Inhibitor
    Cevipabulin(TTI-237) is a novel, potent, synthetic small molecule, inhibits binding of vinblastine at the Vinca alkaloid site of the αβ-tubulin heterodimer.
  • HY-10498
    Lexibulin Inhibitor
    Lexibulin(CYT-997) is a potent tubulin polymerisation inhibitor with IC50 of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo.
  • HY-13627
    Estramustine phosphate sodium Inhibitor
    Estramustine phosphate sodium is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.
  • HY-10340
    KX2-391 Inhibitor
    KX2-391 is an inhibitor of Src that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines.
  • HY-10340A
    KX2-391 dihydrochloride Inhibitor
    KX2-391 (dihydrochloride) is an inhibitor of Src that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines.
  • HY-16114
    BNC105 Inhibitor
    BNC105 is a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.
  • HY-15552
    Podophyllotoxin Inhibitor
    Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II.