PC5-VC-PAB-MMAE
Based on 1 Customer Validation
PC5-VC-PAB-MMAE consists the ADCs linker (PC5-VC-PAB) and potent tubulin inhibitor (MMAE). PC5-VC-PAB-MMAE is a agent-linker conjugate for ADC.
For research use only. We do not sell to patients.
- Purity: 98.91%
- CAS No.: 2922216-98-4
- Formula: C69H99F5N10O15
- Molecular Weight:1403.57
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 2922216-98-4
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Appearance Solid
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Molecular Weight 1403.57
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Formula C69H99F5N10O15
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC(OC4=C(C(F)=C(C(F)=C4F)F)F)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (71.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7125 mL | 3.5623 mL | 7.1247 mL | 17.8117 mL |
| 5 mM | 0.1425 mL | 0.7125 mL | 1.4249 mL | 3.5623 mL | |
| 10 mM | 0.0712 mL | 0.3562 mL | 0.7125 mL | 1.7812 mL | |
| 15 mM | 0.0475 mL | 0.2375 mL | 0.4750 mL | 1.1874 mL | |
| 20 mM | 0.0356 mL | 0.1781 mL | 0.3562 mL | 0.8906 mL | |
| 25 mM | 0.0285 mL | 0.1425 mL | 0.2850 mL | 0.7125 mL | |
| 30 mM | 0.0237 mL | 0.1187 mL | 0.2375 mL | 0.5937 mL | |
| 40 mM | 0.0178 mL | 0.0891 mL | 0.1781 mL | 0.4453 mL | |
| 50 mM | 0.0142 mL | 0.0712 mL | 0.1425 mL | 0.3562 mL | |
| 60 mM | 0.0119 mL | 0.0594 mL | 0.1187 mL | 0.2969 mL |