Signaling Pathway

HCV

HCV

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HCV Inhibitors & Modulators (49)

Product Name Catalog No. Brief Description
ABT-333

HY-13998

ABT-333 is an NS5B non-nucleoside polymerase inhibitor.

Anguizole

HY-13321

Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution.

Artemisinin

HY-B0094

Artemisinin (NSC 369397), a widely used anti-malarial drug, is an inhibitor of HCV subgenomic replicon replication.

Asunaprevir

HY-14434

Asunaprevir (BMS-650032) is a potent hepatitis C virus (HCV) NS3 protease inhibitor.

Balapiravir

HY-10443

Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479).

Beclabuvir

HY-12429

Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.

Boceprevir

HY-10237

Boceprevir(EBP-520, SCH503034) is an HCV protease inhibitor (Ki=14 nM) for the treatment of hepatitis C virus infection.

Celgosivir

HY-16134

Celgosivir is a novel α-glucosidase I inhibitor, an enzyme that plays a critical role in viral maturation by initiating the processing of the N-linked oligosaccharides of viral envelope glycoproteins.

Clemizole hydrochloride

HY-30234A

Clemizole Hcl is a H1 histamine receptor antagonist.

Daclatasvir

HY-10466

Daclatasvir (BMS-790052; EBP 883) is a first-in-class, highly-selective oral HCV NS5A inhibitor.

Daclatasvir dihydrochloride

HY-10465

BMS-790052 is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.

Danoprevir

HY-10238

Danoprevir(ITMN-191;R7227; RO5190591;RG7227) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A.

Elbasvir

HY-15789

Elbasvir (MK-8742) is a small-molecule inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) being developed as a component of treatment regimens for chronic HCV infection.

KIN1408

HY-19961

KIN1408 is an antiviral small molecule compound, as agonists of the RLR pathway.

Ledipasvir

HY-15602

Ledipasvir(GS5885) is an inhibitor of the hepatitis C virus  NS5A protein.

Ledipasvir acetone

HY-15602A

Ledipasvir (GS5885) acetone is an inhibitor of the hepatitis C virus  NS5A protein, which is an experimental drug for the treatment of hepatitis C.

Ledipasvir D-tartrate

HY-15602B

Ledipasvir (GS5885) D-tartrate is an inhibitor of the hepatitis C virus  NS5A protein, which is an experimental drug for the treatment of hepatitis C.

Ledipasvir diacetone

HY-15602D

Ledipasvir(GS5885) diacetone is an inhibitor of the hepatitis C virus NS5A protein; Ledipasvir is an experimental drug for the treatment of hepatitis C.

MK-5172

HY-15298

MK-5172 is a novel P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.

MK-5172 hydrate

HY-15298B

MK-5172 is a novel P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.