1. Screening Libraries
  2. Anti-Lung Cancer Compound Library

Anti-Lung Cancer Compound Library

Cat. No.: HY-L075
Library Contents: XLSX PDF SDF

Lung cancer is a major global health problem, as it is the leading cause of cancer-related deaths worldwide. Lung cancer is divided into two categories: small cell lung cancer and non-small cell lung cancer (NSCLC). Non-small cell lung cancer accounts for about 85 percent of lung cancers.

As with all cancers, lung cancer may be treated with surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy or a combination thereof. Targeted therapy is one of the most exciting developments in lung cancer medicine, especially for NSCLC. Extensive genomic characterization of NSCLC has led to the identification of molecular subtypes of NSCLC that are oncogene addicted and exquisitely sensitive to targeted therapies. These include activating mutations in epidermal growth factor receptor (EGFR) and BRAF or echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusions and ROS1 receptor tyrosine kinase fusions. These are important targets for target therapy.

MCE offers a unique collection of 606 compounds with identified and potential anti-lung cancer activity. These compounds target lung cancer’s major targets and signaling pathways. MCE anti-lung cancer compound library is a useful tool for anti-lung cancer drugs screening and other related research.

MCE Anti-Lung Cancer Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 590 compounds supplied in 10 mM solution, 15 compounds supplied in 2 mM solution and 1 compounds supplied in 3 mg/mL solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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50 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM , 2 mM and 3 mg/mL
Pre-dissolved Solution

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Description
& Advantages

•   A unique collection of 606 compounds with identified and potential anti-lung cancer activity for high throughput screening (HTS) and high content screening (HCS).

•   Targets include EGFR, BRAF, ROS1,ALK,etc.

•   A useful tool for the discovery of anti-lung cancer drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 606 anti-lung cancer compounds supplied as pre-dissolved Solutions or Solid
Solution: 590 compounds supplied in 10 mM solution, 15 compounds supplied in 2 mM solution, 1 compounds supplied in 3 mg/mL solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Composition

Anti-Lung Cancer Compound Library

Source: MedChem Express

Documentation

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    Product Name:
    Anti-Lung Cancer Compound Library
    Cat. No.:
    HY-L075
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    • 96-well Plate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack